Concise Review: Human Induced Pluripotent Stem Cell Models of Retinitis Pigmentosa. 2018, Stem Cells, 36, 474-481, PubMed ID: 29345014
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Establishment of an induced pluripotent stem (iPS) cell line from dermal fibroblasts of an asymptomatic patient with dominant PRPF31 mutation. 2017, Stem Cell Res, 25, 26-29, PubMed ID: 29040912
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Generation of an induced pluripotent stem cell (iPSC) line from a patient with autosomal dominant retinitis pigmentosa due to a mutation in the NR2E3 gene. 2017, Stem Cell Res, 24, 1-4, PubMed ID: 29034877
A. Terray, A. Slembrouck, C. Nanteau, C. Chondroyer, C. Zeitz, J. A. Sahel, I. Audo, S. Reichman and O. Goureau

Retinal regeneration by transplantation of retinal tissue derived from human embryonic or induced pluripotent stem cells. 2016, Inflamm Regen, 36, 2, PubMed ID: 29259675
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Concise Review: Patient-Specific Stem Cells to Interrogate Inherited Eye Disease. 2016, Stem Cells Transl Med, 5, 132-40, PubMed ID: 26683869
J. C. Giacalone, L. A. Wiley, E. R. Burnight, A. E. Songstad, R. F. Mullins, E. M. Stone and B. A. Tucker

Efficient Production of Photoreceptor Precursor Cells from Human Embryonic Stem Cells. 2016, Methods Mol Biol, 1307, 357-69, PubMed ID: 24301073
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Simultaneous Reprogramming and Gene Correction of Patient Fibroblasts. 2015, Stem Cell Reports, 5, 1109-1118, PubMed ID: 26584543
S. E. Howden, J. P. Maufort, B. M. Duffin, A. G. Elefanty, E. G. Stanley and J. A. Thomson

Use of induced pluripotent stem-cell technology to understand photoreceptor cytoskeletal dynamics in retinitis pigmentosa. 2015, Lancet, 385 Suppl 1, S69, PubMed ID: 26312891
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Human iPSC derived disease model of MERTK-associated retinitis pigmentosa. 2015, Sci Rep, 5, 12910, PubMed ID: 26263531
D. Lukovic, A. Artero Castro, A. B. Delgado, L. Bernal Mde, N. Luna Pelaez, A. Diez Lloret, R. Perez Espejo, K. Kamenarova, L. Fernandez Sanchez, N. Cuenca, M. Corton, A. Avila Fernandez, A. Sorkio, H. Skottman, C. Ayuso, S. Erceg and S. S. Bhattacharya

Efficient delivery and functional expression of transfected modified mRNA in human embryonic stem cell-derived retinal pigmented epithelial cells. 2015, J Biol Chem, 290, 5661-72, PubMed ID: 25555917
M. L. Hansson, S. Albert, L. Gonzalez Somermeyer, R. Peco, E. Mejia-Ramirez, N. Montserrat and J. C. Izpisua Belmonte

Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells. 2015, Hum Mol Genet, 24, 972-86, PubMed ID: 25292197
N. Schwarz, A. J. Carr, A. Lane, F. Moeller, L. L. Chen, M. Aguila, B. Nommiste, M. N. Muthiah, N. Kanuga, U. Wolfrum, K. Nagel-Wolfrum, L. da Cruz, P. J. Coffey, M. E. Cheetham and A. J. Hardcastle

The use of induced pluripotent stem cells to reveal pathogenic gene mutations and explore treatments for retinitis pigmentosa. 2014, Mol Brain, 7, 45, PubMed ID: 24935155
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Evaluating the potential of poly(beta-amino ester) nanoparticles for reprogramming human fibroblasts to become induced pluripotent stem cells. 2013, Int J Nanomedicine, 8, 4641-58, PubMed ID: 24348039
N. S. Bhise, K. J. Wahlin, D. J. Zack and J. J. Green

Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa. 2013, Elife, 2, e00824, PubMed ID: 23991284
B. A. Tucker, R. F. Mullins, L. M. Streb, K. Anfinson, M. E. Eyestone, E. Kaalberg, M. J. Riker, A. V. Drack, T. A. Braun and E. M. Stone

Brief report: self-organizing neuroepithelium from human pluripotent stem cells facilitates derivation of photoreceptors. 2013, Stem Cells, 31, 408-14, PubMed ID: 23132794
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Integration-free induced pluripotent stem cells derived from retinitis pigmentosa patient for disease modeling. 2012, Stem Cells Transl Med, 1, 503-9, PubMed ID: 23197854
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Long-term safety and efficacy of human-induced pluripotent stem cell (iPS) grafts in a preclinical model of retinitis pigmentosa. 2012, Mol Med, 18, 1312-9, PubMed ID: 22895806
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Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells. 2009, Stem Cells, 27, 2427-34, PubMed ID: 19658190
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Stem cells from apical papilla promote differentiation of human pluripotent stem cells towards retinal cells. 2018, Differentiation, 101, 8-15, PubMed ID: 29574166
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How human embryonic stem cells sparked a revolution. 2018, Nature, 555, 428-430, PubMed ID: 29565377
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Subretinal Transplantation of Human Embryonic Stem Cell Derived-retinal Pigment Epithelial Cells into a Large-eyed Model of Geographic Atrophy. 2018, J Vis Exp, PubMed ID: 29443034
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Fibrin hydrogels as a xenofree and rapidly degradable support for transplantation of retinal pigment epithelium monolayers. 2018, Acta Biomater, 67, 134-146, PubMed ID: 29233750
J. K. Gandhi, Z. Manzar, L. A. Bachman, C. Andrews-Pfannkoch, T. Knudsen, M. Hill, H. Schmidt, R. Iezzi, J. S. Pulido and A. D. Marmorstein

Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization. 2017, Stem Cell Res Ther, 8, 217, PubMed ID: 28969679
R. A. Hazim, S. Karumbayaram, M. Jiang, A. Dimashkie, V. S. Lopes, D. Li, B. L. Burgess, P. Vijayaraj, J. A. Alva-Ornelas, J. A. Zack, D. B. Kohn, B. N. Gomperts, A. D. Pyle, W. E. Lowry and D. S. Williams

Bioengineered Bruch’s-like extracellular matrix promotes retinal pigment epithelial differentiation. 2017, Biochem Biophys Rep, 10, 178-185, PubMed ID: 28955745
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LncRNA ZNF503-AS1 promotes RPE differentiation by downregulating ZNF503 expression. 2017, Cell Death Dis, 8, e3046, PubMed ID: 28880276
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Sorsby fundus dystrophy – A review of pathology and disease mechanisms. 2017, Exp Eye Res, 165, 35-46, PubMed ID: 28847738
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Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors. 2017, Stem Cell Reports, 9, 820-837, PubMed ID: 28844659
A. Gonzalez-Cordero, K. Kruczek, A. Naeem, M. Fernando, M. Kloc, J. Ribeiro, D. Goh, Y. Duran, S. J. I. Blackford, L. Abelleira-Hervas, R. D. Sampson, I. O. Shum, M. J. Branch, P. J. Gardner, J. C. Sowden, J. W. B. Bainbridge, A. J. Smith, E. L. West, R. A. Pearson and R. R. Ali

Stem Cell Therapies for Reversing Vision Loss. 2017, Trends Biotechnol, 35, 1102-1117, PubMed ID: 28751147
A. Higuchi, S. S. Kumar, G. Benelli, A. A. Alarfaj, M. A. Munusamy, A. Umezawa and K. Murugan

Stem Cell Derived Retinal Pigment Epithelium: The Role of Pigmentation as Maturation Marker and Gene Expression Profile Comparison with Human Endogenous Retinal Pigment Epithelium. 2017, Stem Cell Rev, 13, 659-669, PubMed ID: 28730556
A. Bennis, J. G. Jacobs, L. A. E. Catsburg, J. B. Ten Brink, C. Koster, R. O. Schlingemann, J. van Meurs, T. Gorgels, P. D. Moerland, V. M. Heine and A. A. Bergen

Induced pluripotent stem cell-based therapy for age-related macular degeneration. 2017, Expert Opin Biol Ther, 17, 1113-1126, PubMed ID: 28664762
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Bringing the age-related macular degeneration high-risk allele age-related maculopathy susceptibility 2 into focus with stem cell technology. 2017, Stem Cell Res Ther, 8, 135, PubMed ID: 28583181
S. Sun, Z. Li, P. Glencer, B. Cai, X. Zhang, J. Yang and X. Li

Extracellular matrix nitration alters growth factor release and activates bioactive complement in human retinal pigment epithelial cells. 2017, PLoS One, 12, e0177763, PubMed ID: 28505174
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Progress of stem/progenitor cell-based therapy for retinal degeneration. 2017, J Transl Med, 15, 99, PubMed ID: 28486987
Z. Tang, Y. Zhang, Y. Wang, D. Zhang, B. Shen, M. Luo and P. Gu

Connective Tissue Growth Factor Promotes Efficient Generation of Human Induced Pluripotent Stem Cell-Derived Choroidal Endothelium. 2017, Stem Cells Transl Med, 6, 1533-1546, PubMed ID: 28474838
A. E. Songstad, K. S. Worthington, K. R. Chirco, J. C. Giacalone, S. S. Whitmore, K. R. Anfinson, D. Ochoa, C. M. Cranston, M. J. Riker, M. Neiman, E. M. Stone, R. F. Mullins and B. A. Tucker

Autologous Induced Stem-Cell-Derived Retinal Cells for Macular Degeneration. 2017, N Engl J Med, 376, 1038-1046, PubMed ID: 28296613
M. Mandai, A. Watanabe, Y. Kurimoto, Y. Hirami, C. Morinaga, T. Daimon, M. Fujihara, H. Akimaru, N. Sakai, Y. Shibata, M. Terada, Y. Nomiya, S. Tanishima, M. Nakamura, H. Kamao, S. Sugita, A. Onishi, T. Ito, K. Fujita, S. Kawamata, M. J. Go, C. Shinohara, K. I. Hata, M. Sawada, M. Yamamoto, S. Ohta, Y. Ohara, K. Yoshida, J. Kuwahara, Y. Kitano, N. Amano, M. Umekage, F. Kitaoka, A. Tanaka, C. Okada, N. Takasu, S. Ogawa, S. Yamanaka and M. Takahashi

Generation of retinal pigmented epithelium from iPSCs derived from the conjunctiva of donors with and without age related macular degeneration. 2017, PLoS One, 12, e0173575, PubMed ID: 28282420
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Directing Differentiation of Pluripotent Stem Cells Toward Retinal Pigment Epithelium Lineage. 2017, Stem Cells Transl Med, 6, 490-501, PubMed ID: 28191760
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Stem Cell Therapies in Retinal Disorders. 2017, Cells, 6, PubMed ID: 28157165
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Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration. 2017, Cell Stem Cell, 20, 635-647.e7, PubMed ID: 28132833
J. S. Saini, B. Corneo, J. D. Miller, T. R. Kiehl, Q. Wang, N. C. Boles, T. A. Blenkinsop, J. H. Stern and S. Temple

Repressed SIRT1/PGC-1alpha pathway and mitochondrial disintegration in iPSC-derived RPE disease model of age-related macular degeneration. 2016, J Transl Med, 14, 344, PubMed ID: 27998274
N. Golestaneh, Y. Chu, S. K. Cheng, H. Cao, E. Poliakov and D. M. Berinstein

Reductive carboxylation is a major metabolic pathway in the retinal pigment epithelium. 2016, Proc Natl Acad Sci U S A, 113, 14710-14715, PubMed ID: 27911769
J. Du, A. Yanagida, K. Knight, A. L. Engel, A. H. Vo, C. Jankowski, M. Sadilek, V. T. Tran, M. A. Manson, A. Ramakrishnan, J. B. Hurley and J. R. Chao

MicroRNA-184 promotes differentiation of the retinal pigment epithelium by targeting the AKT2/mTOR signaling pathway. 2016, Oncotarget, 7, 52340-52353, PubMed ID: 27418134
C. Jiang, B. Qin, G. Liu, X. Sun, H. Shi, S. Ding, Y. Liu, M. Zhu, X. Chen and C. Zhao

[Retinal Cell Therapy Using iPS Cells]. 2016, Nippon Ganka Gakkai Zasshi, 120, 210-24; discussion 225, PubMed ID: 27164758
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Stem Cell Therapy in Nonneovascular Age-Related Macular Degeneration. 2016, Invest Ophthalmol Vis Sci, 57, ORSFm1-9, PubMed ID: 27116669
A. H. Kashani

Treatment Paradigms for Retinal and Macular Diseases Using 3-D Retina Cultures Derived From Human Reporter Pluripotent Stem Cell Lines. 2016, Invest Ophthalmol Vis Sci, 57, ORSFl1-ORSFl11, PubMed ID: 27116668
R. Kaewkhaw, M. Swaroop, K. Homma, J. Nakamura, M. Brooks, K. D. Kaya, V. Chaitankar, S. Michael, G. Tawa, J. Zou, M. Rao, W. Zheng, T. Cogliati and A. Swaroop

Targeting the cAMP and Transforming Growth Factor-beta Pathway Increases Proliferation to Promote Re-Epithelialization of Human Stem Cell-Derived Retinal Pigment Epithelium. 2016, Stem Cells Transl Med, 5, 925-37, PubMed ID: 27112176
P. Choudhary, A. Gutteridge, E. Impey, R. I. Storer, R. M. Owen, P. J. Whiting, M. Bictash and C. L. Benn

The germline/soma dichotomy: implications for aging and degenerative disease. 2016, Regen Med, 11, 331-4, PubMed ID: 27035399
M. D. West, F. Binette, D. Larocca, K. B. Chapman, C. Irving and H. Sternberg

Transcriptional Reactivation of OTX2, RX1 and SIX3 during Reprogramming Contributes to the Generation of RPE Cells from Human iPSCs. 2016, Int J Biol Sci, 12, 505-17, PubMed ID: 27019633
P. Li, X. Sun, Z. Ma, Y. Liu, Y. Jin, R. Ge, L. Hao, Y. Ma, S. Han, H. Sun, M. Zhang, R. Li, T. Li and L. Shen

Stem Cell-Based Therapy for Diseases of the Retinal Pigment Epithelium: From Bench to Bedside. 2016, Semin Ophthalmol, 31, 25-9, PubMed ID: 26959126
M. M. Sachdeva and D. Eliott

The Silk-protein Sericin Induces Rapid Melanization of Cultured Primary Human Retinal Pigment Epithelial Cells by Activating the NF-kappaB Pathway. 2016, Sci Rep, 6, 22671, PubMed ID: 26940175
J. R. Eidet, S. Reppe, L. Pasovic, O. K. Olstad, T. Lyberg, A. Z. Khan, I. G. Fostad, D. F. Chen and T. P. Utheim

Techniques of Human Embryonic Stem Cell and Induced Pluripotent Stem Cell Derivation. 2016, Arch Immunol Ther Exp (Warsz), 64, 349-70, PubMed ID: 26939778
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Honeycomb porous films as permeable scaffold materials for human embryonic stem cell-derived retinal pigment epithelium. 2016, J Biomed Mater Res A, 104, 1646-56, PubMed ID: 26914698
M. T. Calejo, T. Ilmarinen, H. Jongprasitkul, H. Skottman and M. Kellomaki

Cell-Based Therapy for Degenerative Retinal Disease. 2016, Trends Mol Med, 22, 115-134, PubMed ID: 26791247
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Xeno-Free and Defined Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells Functionally Integrate in a Large-Eyed Preclinical Model. 2016, Stem Cell Reports, 6, 9-17, PubMed ID: 26724907
A. Plaza Reyes, S. Petrus-Reurer, L. Antonsson, S. Stenfelt, H. Bartuma, S. Panula, T. Mader, I. Douagi, H. Andre, O. Hovatta, F. Lanner and A. Kvanta

Concise Review: Patient-Specific Stem Cells to Interrogate Inherited Eye Disease. 2016, Stem Cells Transl Med, 5, 132-40, PubMed ID: 26683869
J. C. Giacalone, L. A. Wiley, E. R. Burnight, A. E. Songstad, R. F. Mullins, E. M. Stone and B. A. Tucker

Human embryonic stem cells. 2016, Best Pract Res Clin Obstet Gynaecol, 31, 2-12, PubMed ID: 26602389
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Modeling Kidney Disease with iPS Cells. 2015, Biomark Insights, 10, 153-69, PubMed ID: 26740740
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Differentiation of Human Protein-Induced Pluripotent Stem Cells toward a Retinal Pigment Epithelial Cell Fate. 2015, PLoS One, 10, e0143272, PubMed ID: 26606685
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Modeling the Dynamic AMD-Associated Chronic Oxidative Stress Changes in Human ESC and iPSC-Derived RPE Cells. 2015, Invest Ophthalmol Vis Sci, 56, 7480-8, PubMed ID: 26595608
T. Y. Garcia, M. Gutierrez, J. Reynolds and D. A. Lamba

Transplantation of rat embryonic stem cell-derived retinal progenitor cells preserves the retinal structure and function in rat retinal degeneration. 2015, Stem Cell Res Ther, 6, 219, PubMed ID: 26553210
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Histone Demethylase Expression Enhances Human Somatic Cell Nuclear Transfer Efficiency and Promotes Derivation of Pluripotent Stem Cells. 2015, Cell Stem Cell, 17, 758-766, PubMed ID: 26526725
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Current status of pluripotent stem cells: moving the first therapies to the clinic. 2015, Nat Rev Drug Discov, 14, 681-92, PubMed ID: 26391880
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Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells. 2015, Cell Stem Cell, 17, 353-9, PubMed ID: 26299572
T. Zhao, Z. N. Zhang, P. D. Westenskow, D. Todorova, Z. Hu, T. Lin, Z. Rong, J. Kim, J. He, M. Wang, D. O. Clegg, Y. G. Yang, K. Zhang, M. Friedlander and Y. Xu

Small-molecule-directed, efficient generation of retinal pigment epithelium from human pluripotent stem cells. 2015, Proc Natl Acad Sci U S A, 112, 10950-5, PubMed ID: 26269569
J. Maruotti, S. R. Sripathi, K. Bharti, J. Fuller, K. J. Wahlin, V. Ranganathan, V. M. Sluch, C. A. Berlinicke, J. Davis, C. Kim, L. Zhao, J. Wan, J. Qian, B. Corneo, S. Temple, R. Dubey, B. Z. Olenyuk, I. Bhutto, G. A. Lutty and D. J. Zack

Stem cell based therapies for age-related macular degeneration: The promises and the challenges. 2015, Prog Retin Eye Res, 48, 1-39, PubMed ID: 26113213
H. Nazari, L. Zhang, D. Zhu, G. J. Chader, P. Falabella, F. Stefanini, T. Rowland, D. O. Clegg, A. H. Kashani, D. R. Hinton and M. S. Humayun

Variability of miRNA expression during the differentiation of human embryonic stem cells into retinal pigment epithelial cells. 2015, Gene, 569, 239-49, PubMed ID: 26028588
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Prospects for clinical use of reprogrammed cells for autologous treatment of macular degeneration. 2015, Fibrogenesis Tissue Repair, 8, 9, PubMed ID: 25984235
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Treatment of macular degeneration using embryonic stem cell-derived retinal pigment epithelium: preliminary results in Asian patients. 2015, Stem Cell Reports, 4, 860-72, PubMed ID: 25937371
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Concise Review: Making Stem Cells Retinal: Methods for Deriving Retinal Pigment Epithelium and Implications for Patients With Ocular Disease. 2015, Stem Cells, 33, 2363-73, PubMed ID: 25809736
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Stem cell therapy for retinal diseases. 2015, World J Stem Cells, 7, 160-4, PubMed ID: 25621115
J. M. Garcia, L. Mendonca, R. Brant, M. Abud, C. Regatieri and B. Diniz

Stem cell therapies for age-related macular degeneration: the past, present, and future. 2015, Clin Interv Aging, 10, 255-64, PubMed ID: 25609937
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Canonical/beta-catenin Wnt pathway activation improves retinal pigmented epithelium derivation from human embryonic stem cells. 2015, Invest Ophthalmol Vis Sci, 56, 1002-13, PubMed ID: 25604686
L. L. Leach, D. E. Buchholz, V. P. Nadar, S. E. Lowenstein and D. O. Clegg

Defined culture of human embryonic stem cells and xeno-free derivation of retinal pigmented epithelial cells on a novel, synthetic substrate. 2015, Stem Cells Transl Med, 4, 165-77, PubMed ID: 25593208
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Efficient delivery and functional expression of transfected modified mRNA in human embryonic stem cell-derived retinal pigmented epithelial cells. 2015, J Biol Chem, 290, 5661-72, PubMed ID: 25555917
M. L. Hansson, S. Albert, L. Gonzalez Somermeyer, R. Peco, E. Mejia-Ramirez, N. Montserrat and J. C. Izpisua Belmonte

Deprivation of bFGF Promotes Spontaneous Differentiation of Human Embryonic Stem Cells into Retinal Pigment Epithelial Cells. 2015, J Stem Cells, 10, 159-70, PubMed ID: 27125061
L. R. Ferguson, S. Balaiya, B. K. Mynampati, K. Sambhav and K. V. Chalam

Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt’s macular dystrophy: follow-up of two open-label phase 1/2 studies. 2015, Lancet, 385, 509-16, PubMed ID: 25458728
S. D. Schwartz, C. D. Regillo, B. L. Lam, D. Eliott, P. J. Rosenfeld, N. Z. Gregori, J. P. Hubschman, J. L. Davis, G. Heilwell, M. Spirn, J. Maguire, R. Gay, J. Bateman, R. M. Ostrick, D. Morris, M. Vincent, E. Anglade, L. V. Del Priore and R. Lanza

Polarized human embryonic stem cell-derived retinal pigment epithelial cell monolayers have higher resistance to oxidative stress-induced cell death than nonpolarized cultures. 2015, Stem Cells Transl Med, 4, 10-20, PubMed ID: 25411476
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Engineering efficient retinal pigment epithelium differentiation from human pluripotent stem cells. 2014, Stem Cells Transl Med, 3, 1295-304, PubMed ID: 25273541
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ROCK Inhibition Extends Passage of Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium. 2014, Stem Cells Transl Med, 3, 1066-78, PubMed ID: 25069775
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Differentiation of pluripotent stem cells into retinal pigmented epithelium. 2014, Dev Ophthalmol, 53, 81-96, PubMed ID: 24732763
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Characterization of human induced pluripotent stem cell-derived retinal pigment epithelium cell sheets aiming for clinical application. 2014, Stem Cell Reports, 2, 205-18, PubMed ID: 24527394
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Direct conversion of human fibroblasts into retinal pigment epithelium-like cells by defined factors. 2014, Protein Cell, 5, 48-58, PubMed ID: 24474194
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The immunogenicity of cells derived from induced pluripotent stem cells. 2014, Cell Mol Immunol, 11, 14-6, PubMed ID: 24336164
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Retinal repair with induced pluripotent stem cells. 2014, Transl Res, 163, 377-86, PubMed ID: 24291154
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