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神経系分化誘導法掲載論文一覧


Optogenetic control of iPS cell-derived neurons in 2D and 3D culture systems using channelrhodopsin-2 expressed by the SYN1 and CaMKII promoters. 2018, J Tissue Eng Regen Med, PubMed ID: 30550638
S. Y. Lee, J. H. George, D. A. Nagel, H. Ye, G. Kueberuwa and L. W. Seymour

A Comprehensive Analysis of Protocols for Deriving Dopaminergic Neurons from Human Pluripotent Stem Cells. 2018, Stem Cells Transl Med, PubMed ID: 30537442
R. M. Marton and J. P. A. Ioannidis

Treatment with a Gamma-Secretase Inhibitor Promotes Functional Recovery in Human iPSC- Derived Transplants for Chronic Spinal Cord Injury. 2018, Stem Cell Reports, 11, 1416-1432, PubMed ID: 30503258
T. Okubo, N. Nagoshi, J. Kohyama, O. Tsuji, M. Shinozaki, S. Shibata, Y. Kase, M. Matsumoto, M. Nakamura and H. Okano

Pluripotent Stem Cells for Modelling and Cell Therapy of Parkinson’s Disease. 2018, Biochemistry (Mosc), 83, 1046-1056, PubMed ID: 30472943
O. S. Lebedeva and M. A. Lagarkova

Best Practices for Translational Disease Modeling Using Human iPSC-Derived Neurons. 2018, Neuron, 100, 783-797, PubMed ID: 30465765
S. J. Engle, L. Blaha and R. J. Kleiman

Inhibition of Lithium Sensitive Orai1/ STIM1 Expression and Store Operated Ca2+ Entry in Chorea-Acanthocytosis Neurons by NF-kappaB Inhibitor Wogonin. 2018, Cell Physiol Biochem, 51, 278-289, PubMed ID: 30453283
B. Sukkar, S. Hauser, L. Pelzl, Z. Hosseinzadeh, I. Sahu, T. Al-Maghout, A. A. M. Bhuyan, N. Zacharopoulou, C. Stournaras, L. Schols and F. Lang

The effect of rho kinase inhibition on morphological and electrophysiological maturity in iPSC-derived neurons. 2018, Cell Tissue Res, PubMed ID: 30406823
L. J. Harbom, T. L. Rudisill, N. Michel, K. A. Litwa, M. P. Beenhakker and M. J. McConnell

Human Huntington’s Disease iPSC-Derived Cortical Neurons Display Altered Transcriptomics, Morphology, and Maturation. 2018, Cell Rep, 25, 1081-1096.e6, PubMed ID: 30355486
S. R. Mehta, C. M. Tom, Y. Wang, C. Bresee, D. Rushton, P. P. Mathkar, J. Tang and V. B. Mattis

MicroRNA-132 directs human periodontal ligament-derived neural crest stem cell neural differentiation. 2018, J Tissue Eng Regen Med, PubMed ID: 30352481
T. K. Ng, Q. Yang, V. R. Fortino, N. Y. Lai, C. M. Carballosa, J. M. Greenberg, K. W. Choy, D. Pelaez, C. P. Pang and H. S. Cheung

Human Cortical Neuron Generation Using Cell Reprogramming: A Review of Recent Advances. 2018, Stem Cells Dev, PubMed ID: 30343634
A. McCaughey-Chapman and B. Connor

Expression and secretion of synaptic proteins during stem cell differentiation to cortical neurons. 2018, Neurochem Int, 121, 38-49, PubMed ID: 30342961
F. H. Nazir, B. Becker, A. Brinkmalm, K. Hoglund, A. Sandelius, P. Bergstrom, T. M. Satir, A. Ohrfelt, K. Blennow, L. Agholme and H. Zetterberg

Hair-Follicle-Associated Pluripotent (HAP) Stem Cells Encapsulated on Polyvinylidene Fluoride Membranes (PFM) Promote Functional Recovery from Spinal Cord Injury. 2018, Stem Cell Rev, PubMed ID: 30341634
K. Obara, N. Tohgi, K. Shirai, S. Mii, Y. Hamada, N. Arakawa, R. Aki, S. R. Singh, R. M. Hoffman and Y. Amoh

The Use of Stem Cell-Derived Neurons for Understanding Development and Disease of the Cerebellum. 2018, Front Neurosci, 12, 646, PubMed ID: 30319335
S. P. Nayler and E. B. E. Becker

Thyroid hormone signaling specifies cone subtypes in human retinal organoids. 2018, Science, 362, PubMed ID: 30309916
K. C. Eldred, S. E. Hadyniak, K. A. Hussey, B. Brenerman, P. W. Zhang, X. Chamling, V. M. Sluch, D. S. Welsbie, S. Hattar, J. Taylor, K. Wahlin, D. J. Zack and R. J. Johnston, Jr.

Rapid and efficient differentiation of functional motor neurons from human iPSC for neural injury modelling. 2018, Stem Cell Res, 32, 126-134, PubMed ID: 30278374
F. Bianchi, M. Malboubi, Y. Li, J. H. George, A. Jerusalem, F. Szele, M. S. Thompson and H. Ye

Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study. 2018, Stem Cell Reports, 11, 897-911, PubMed ID: 30245212
V. Volpato, J. Smith, C. Sandor, J. S. Ried, A. Baud, A. Handel, S. E. Newey, F. Wessely, M. Attar, E. Whiteley, S. Chintawar, A. Verheyen, T. Barta, M. Lako, L. Armstrong, C. Muschet, A. Artati, C. Cusulin, K. Christensen, C. Patsch, E. Sharma, J. Nicod, P. Brownjohn, V. Stubbs, W. E. Heywood, P. Gissen, R. De Filippis, K. Janssen, P. Reinhardt, J. Adamski, I. Royaux, P. J. Peeters, G. C. Terstappen, M. Graf, F. J. Livesey, C. J. Akerman, K. Mills, R. Bowden, G. Nicholson, C. Webber, M. Z. Cader and V. Lakics

Single-Step Plasmid Based Reprogramming of Human Dermal Fibroblasts to Induced Neural Stem Cells. 2018, Methods Mol Biol, 1842, 31-41, PubMed ID: 30196399
L. Azmitia and P. Capetian

Synaptic Microcircuit Modeling with 3D Cocultures of Astrocytes and Neurons from Human Pluripotent Stem Cells. 2018, J Vis Exp, PubMed ID: 30176009
C. Cvetkovic, N. Basu and R. Krencik

A Chemical Recipe for Generation of Clinical-Grade Striatal Neurons from hESCs. 2018, Stem Cell Reports, 11, 635-650, PubMed ID: 30174316
M. Wu, D. Zhang, C. Bi, T. Mi, W. Zhu, L. Xia, Z. Teng, B. Hu and Y. Wu

Patterning factors during neural progenitor induction determine regional identity and differentiation potential in vitro. 2018, Stem Cell Res, 32, 25-34, PubMed ID: 30172094
A. G. Nadadhur, P. S. Leferink, D. Holmes, L. Hinz, P. Cornelissen-Steijger, L. Gasparotto and V. M. Heine

Human iPSC-derived trigeminal neurons lack constitutive TLR3-dependent immunity that protects cortical neurons from HSV-1 infection. 2018, Proc Natl Acad Sci U S A, 115, E8775-e8782, PubMed ID: 30154162
B. Zimmer, O. Ewaleifoh, O. Harschnitz, Y. S. Lee, C. Peneau, J. L. McAlpine, B. Liu, J. Tchieu, J. A. Steinbeck, F. Lafaille, S. Volpi, L. D. Notarangelo, J. L. Casanova, S. Y. Zhang, G. A. Smith and L. Studer

Efficient derivation of sympathetic neurons from human pluripotent stem cells with a defined condition. 2018, Sci Rep, 8, 12865, PubMed ID: 30150715
K. Kirino, T. Nakahata, T. Taguchi and M. K. Saito

Neural progenitors derived from Tuberous Sclerosis Complex patients exhibit attenuated PI3K/AKT signaling and delayed neuronal differentiation. 2018, Mol Cell Neurosci, 92, 149-163, PubMed ID: 30144504
A. J. Zucco, V. D. Pozzo, A. Afinogenova, R. P. Hart, O. Devinsky and G. D’Arcangelo

Differentiation of Glial Cells From hiPSCs: Potential Applications in Neurological Diseases and Cell Replacement Therapy. 2018, Front Cell Neurosci, 12, 239, PubMed ID: 30140204
W. Zheng, Q. Li, C. Zhao, Y. Da, H. L. Zhang and Z. Chen

Induced pluripotent stem cells as a tool to study brain circuits in autism-related disorders. 2018, Stem Cell Res Ther, 9, 226, PubMed ID: 30139379
A. Vitrac and I. Cloez-Tayarani

Hydrogel-Based Bioprocess for Scalable Manufacturing of Human Pluripotent Stem Cell-Derived Neural Stem Cells. 2018, ACS Appl Mater Interfaces, 10, 29238-29250, PubMed ID: 30091584
H. Lin, Q. Du, Q. Li, O. Wang, Z. Wang, K. Liu, C. Elowsky, C. Zhang and Y. Lei

Application of pluripotent stem cells for treatment of human neuroendocrine disorders. 2018, Cell Tissue Res, PubMed ID: 30078102
H. Suga

Loss of the fragile X mental retardation protein causes aberrant differentiation in human neural progenitor cells. 2018, Sci Rep, 8, 11585, PubMed ID: 30072797
N. Sunamura, S. Iwashita, K. Enomoto, T. Kadoshima and F. Isono

Application of amphiphilic fluorophore-derived nanoparticles to provide contrast to human embryonic stem cells without affecting their pluripotency and to monitor their differentiation into neuron-like cells. 2018, Acta Biomater, 78, 274-284, PubMed ID: 30071352
S. Zhou, H. Zhao, R. Feng, L. Ding, Z. Li, C. Deng, Q. He, Y. Liu, B. Song and Y. Li

Three-dimensional induction of dorsal, intermediate and ventral spinal cord tissues from human pluripotent stem cells. 2018, Development, 145, PubMed ID: 30061169
T. Ogura, H. Sakaguchi, S. Miyamoto and J. Takahashi

Timing of Wnt Inhibition Modulates Directed Differentiation of Medial Ganglionic Eminence Progenitors from Human Pluripotent Stem Cells. 2018, Stem Cells Int, 2018, 3983090, PubMed ID: 30050576
I. Ihnatovych, A. Lew, E. Lazar, A. Sheng, T. Kellermayer and K. Szigeti

Notch signaling in human iPS-derived neuronal progenitor lines from Focal Cortical Dysplasia patients. 2018, Int J Dev Neurosci, 69, 112-118, PubMed ID: 30048676
F. Majolo, D. R. Marinowic, D. C. Machado and J. C. Da Costa

Generation of a human induced pluripotent stem cell-based model for tauopathies combining three microtubule-associated protein TAU mutations which displays several phenotypes linked to neurodegeneration. 2018, Alzheimers Dement, 14, 1261-1280, PubMed ID: 30036493
J. A. Garcia-Leon, A. Cabrera-Socorro, K. Eggermont, A. Swijsen, J. Terryn, R. Fazal, F. Nami, L. Ordovas, A. Quiles, F. Lluis, L. Serneels, K. Wierda, A. Sierksma, M. Kreir, F. Pestana, P. Van Damme, B. De Strooper, L. Thorrez, A. Ebneth and C. M. Verfaillie

Human cellular models of medium spiny neuron development and Huntington disease. 2018, Life Sci, 209, 179-196, PubMed ID: 30031060
M. M. Golas

The Use of Stem Cells in Neural Regeneration: A Review of Current Opinion. 2018, Curr Stem Cell Res Ther, 13, 608-617, PubMed ID: 30027853
Y. Wang, J. Pan, D. Wang and J. Liu

Generation of dopamine neuronal-like cells from induced neural precursors derived from adult human cells by non-viral expression of lineage factors. 2018, J Stem Cells Regen Med, 14, 34-44, PubMed ID: 30018471
R. Playne, K. Jones and B. Connor

Small Molecule-Based Retinal Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells. 2018, Bio Protoc, 8, PubMed ID: 30009216
J. Zhu and D. A. Lamba

Regulation of cyclin E1 expression in human pluripotent stem cells and derived neural progeny. 2018, Cell Cycle, 17, 1721-1744, PubMed ID: 29995582
M. S. Rodriguez Varela, S. Mucci, G. A. Videla Richardson, O. Morris Hanon, V. A. Furmento, S. G. Miriuka, G. E. Sevlever, M. E. Scassa and L. Romorini

Full Factorial Microfluidic Designs and Devices for Parallelizing Human Pluripotent Stem Cell Differentiation. 2018, SLAS Technol, 2472630318783497, PubMed ID: 29995450
D. M. Chadly, A. M. Oleksijew, K. S. Coots, J. J. Fernandez, S. Kobayashi, J. A. Kessler and A. J. Matsuoka

Induced pluripotent stem cells (iPSCs) as model to study inherited defects of neurotransmission in inborn errors of metabolism. 2018, J Inherit Metab Dis, PubMed ID: 29980968
S. Jung-Klawitter and T. Opladen

Transcription factor induced conversion of human fibroblasts towards the hair cell lineage. 2018, PLoS One, 13, e0200210, PubMed ID: 29979748
M. B. Duran Alonso, I. Lopez Hernandez, M. A. de la Fuente, J. Garcia-Sancho, F. Giraldez and T. Schimmang

Synthetic far-red light-mediated CRISPR-dCas9 device for inducing functional neuronal differentiation. 2018, Proc Natl Acad Sci U S A, 115, E6722-e6730, PubMed ID: 29967137
J. Shao, M. Wang, G. Yu, S. Zhu, Y. Yu, B. C. Heng, J. Wu and H. Ye

Sequential Application of Discrete Topographical Patterns Enhances Derivation of Functional Mesencephalic Dopaminergic Neurons from Human Induced Pluripotent Stem Cells. 2018, Sci Rep, 8, 9567, PubMed ID: 29934644
K. K. B. Tan, W. W. M. Lim, C. Chai, M. Kukumberg, K. L. Lim, E. L. K. Goh and E. K. F. Yim

Transcription Factor-Mediated Differentiation of Human iPSCs into Neurons. 2018, Curr Protoc Cell Biol, 79, e51, PubMed ID: 29924488
M. S. Fernandopulle, R. Prestil, C. Grunseich, C. Wang, L. Gan and M. E. Ward

Transdifferentiation of human adult peripheral blood T cells into neurons. 2018, Proc Natl Acad Sci U S A, 115, 6470-6475, PubMed ID: 29866841
K. Tanabe, C. E. Ang, S. Chanda, V. H. Olmos, D. Haag, D. F. Levinson, T. C. Sudhof and M. Wernig

[Challenges to Improve the Prediction Accuracy of the Non-clinical Tests for Human CNS Adverse Effects: Potentials of Artificial Intelligence and Human ESC/iPSC-derived Neurons]. 2018, Yakugaku Zasshi, 138, 807, PubMed ID: 29863051
K. Sato and Y. Ikegaya

The Impact of APP on Alzheimer-like Pathogenesis and Gene Expression in Down Syndrome iPSC-Derived Neurons. 2018, Stem Cell Reports, 11, 32-42, PubMed ID: 29861166
D. A. Ovchinnikov, O. Korn, I. Virshup, C. A. Wells and E. J. Wolvetang

Robust Induction of DARPP32-Expressing GABAergic Striatal Neurons from Human Pluripotent Stem Cells. 2018, Methods Mol Biol, 1780, 585-605, PubMed ID: 29856037
M. Fjodorova and M. Li

Cellular Models: HD Patient-Derived Pluripotent Stem Cells. 2018, Methods Mol Biol, 1780, 41-73, PubMed ID: 29856014
C. Geater, S. Hernandez, L. Thompson and V. B. Mattis

Convergent Pathways in Idiopathic Autism Revealed by Time Course Transcriptomic Analysis of Patient-Derived Neurons. 2018, Sci Rep, 8, 8423, PubMed ID: 29849033
B. A. DeRosa, J. El Hokayem, E. Artimovich, C. Garcia-Serje, A. W. Phillips, D. Van Booven, J. E. Nestor, L. Wang, M. L. Cuccaro, J. M. Vance, M. A. Pericak-Vance, H. N. Cukier, M. W. Nestor and D. M. Dykxhoorn

Discovery of Novel Cell Surface Markers for Purification of Embryonic Dopamine Progenitors for Transplantation in Parkinson’s Disease Animal Models. 2018, Mol Cell Proteomics, 17, 1670-1684, PubMed ID: 29848781
A. Fathi, M. Mirzaei, B. Dolatyar, M. Sharifitabar, M. Bayat, E. Shahbazi, J. Lee, M. Javan, S. C. Zhang, V. Gupta, B. Lee, P. A. Haynes, H. Baharvand and G. H. Salekdeh

Generation of H1 PAX6(WT/EGFP) reporter cells to purify PAX6 positive neural stem/progenitor cells. 2018, Biochem Biophys Res Commun, 502, 442-449, PubMed ID: 29807013
W. Wu, J. Liu, Z. Su, Z. Li, N. Ma, K. Huang, T. Zhou and L. Wang

Motor neuron differentiation of iPSCs obtained from peripheral blood of a mutant TARDBP ALS patient. 2018, Stem Cell Res, 30, 61-68, PubMed ID: 29800782
P. Bossolasco, F. Sassone, V. Gumina, S. Peverelli, M. Garzo and V. Silani

Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons. 2018, Pflugers Arch, 470, 1359-1376, PubMed ID: 29797067
V. Telezhkin, M. Straccia, P. Yarova, M. Pardo, S. Yung, N. N. Vinh, J. M. Hancock, G. G. Barriga, D. A. Brown, A. E. Rosser, J. T. Brown, J. M. Canals, A. D. Randall, N. D. Allen and P. J. Kemp

Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission. 2018, Cell Rep, 23, 2509-2523, PubMed ID: 29791859
R. Nehme, E. Zuccaro, S. D. Ghosh, C. Li, J. L. Sherwood, O. Pietilainen, L. E. Barrett, F. Limone, K. A. Worringer, S. Kommineni, Y. Zang, D. Cacchiarelli, A. Meissner, R. Adolfsson, S. Haggarty, J. Madison, M. Muller, P. Arlotta, Z. Fu, G. Feng and K. Eggan

Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS. 2018, Nat Commun, 9, 2010, PubMed ID: 29789581
R. Luisier, G. E. Tyzack, C. E. Hall, J. S. Mitchell, H. Devine, D. M. Taha, B. Malik, I. Meyer, L. Greensmith, J. Newcombe, J. Ule, N. M. Luscombe and R. Patani

An integrated biomanufacturing platform for the large-scale expansion and neuronal differentiation of human pluripotent stem cell-derived neural progenitor cells. 2018, Acta Biomater, 74, 168-179, PubMed ID: 29775730
G. Srinivasan, D. Morgan, D. Varun, N. Brookhouser and D. A. Brafman

A scale out approach towards neural induction of human induced pluripotent stem cells for neurodevelopmental toxicity studies. 2018, Toxicol Lett, 294, 51-60, PubMed ID: 29775723
C. C. Miranda, T. G. Fernandes, S. N. Pinto, M. Prieto, M. M. Diogo and J. M. S. Cabral

Modelling the dorsal root ganglia using human pluripotent stem cells: A platform to study peripheral neuropathies. 2018, Int J Biochem Cell Biol, 100, 61-68, PubMed ID: 29772357
S. Viventi and M. Dottori

Basal glucocorticoid receptor activation induces proliferation and inhibits neuronal differentiation of human induced pluripotent stem cell-derived neuronal precursor cells. 2018, J Steroid Biochem Mol Biol, 182, 119-126, PubMed ID: 29751108
E. Nurnberg, S. Horschitz, P. Schloss and A. Meyer-Lindenberg

NKX6.1 induced pluripotent stem cell reporter lines for isolation and analysis of functionally relevant neuronal and pancreas populations. 2018, Stem Cell Res, 29, 220-231, PubMed ID: 29734117
S. K. Gupta, A. Wesolowska-Andersen, A. K. Ringgaard, H. Jaiswal, L. Song, B. Hastoy, C. Ingvorsen, A. Taheri-Ghahfarokhi, B. Magnusson, M. Maresca, R. R. Jensen, N. L. Beer, J. J. Fels, L. G. Grunnet, M. K. Thomas, A. L. Gloyn, R. Hicks, M. I. McCarthy, M. Hansson and C. Honore

Variation in the Phenotype of Photosensitive Cells Produced from Human Fibroblast Cell Lines. 2018, J Nippon Med Sch, 85, 110-116, PubMed ID: 29731494
T. Ishii, C. Yin, Y. Seko, A. Umezawa and M. Kaneda

Efficient Generation of CA3 Neurons from Human Pluripotent Stem Cells Enables Modeling of Hippocampal Connectivity In Vitro. 2018, Cell Stem Cell, 22, 684-697.e9, PubMed ID: 29727680
A. Sarkar, A. Mei, A. C. M. Paquola, S. Stern, C. Bardy, J. R. Klug, S. Kim, N. Neshat, H. J. Kim, M. Ku, M. N. Shokhirev, D. H. Adamowicz, M. C. Marchetto, R. Jappelli, J. A. Erwin, K. Padmanabhan, M. Shtrahman, X. Jin and F. H. Gage

Update on the Role of Stem Cells in the Treatment of Hirschsprung Disease. 2018, Eur J Pediatr Surg, 28, 215-221, PubMed ID: 29689583
K. N. Lui, P. K. H. Tam and E. S. Ngan

Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering. 2018, Cell Rep, 23, 899-908, PubMed ID: 29669293
S. M. Maffioletti, S. Sarcar, A. B. H. Henderson, I. Mannhardt, L. Pinton, L. A. Moyle, H. Steele-Stallard, O. Cappellari, K. E. Wells, G. Ferrari, J. S. Mitchell, G. E. Tyzack, V. N. Kotiadis, M. Khedr, M. Ragazzi, W. Wang, M. R. Duchen, R. Patani, P. S. Zammit, D. J. Wells, T. Eschenhagen and F. S. Tedesco

Directing neuronal cell fate in vitro: Achievements and challenges. 2018, Prog Neurobiol, 168, 42-68, PubMed ID: 29653249
R. J. M. Riemens, D. L. A. van den Hove, M. Esteller and R. Delgado-Morales

Wnt signal activation induces midbrain specification through direct binding of the beta-catenin/TCF4 complex to the EN1 promoter in human pluripotent stem cells. 2018, Exp Mol Med, 50, 24, PubMed ID: 29650976
J. Y. Kim, J. S. Lee, H. S. Hwang, D. R. Lee, C. Y. Park, S. J. Jung, Y. R. You, D. S. Kim and D. W. Kim

MicroRNA profiling during directed differentiation of cortical interneurons from human-induced pluripotent stem cells. 2018, FEBS Open Bio, 8, 502-512, PubMed ID: 29632804
J. Tu, D. Cao, L. Li, H. H. Cheung and W. Y. Chan

Open chromatin dynamics reveals stage-specific transcriptional networks in hiPSC-based neurodevelopmental model. 2018, Stem Cell Res, 29, 88-98, PubMed ID: 29631039
S. Zhang, W. Moy, H. Zhang, C. Leites, H. McGowan, J. Shi, A. R. Sanders, Z. P. Pang, P. V. Gejman and J. Duan

The telomerase inhibitor AZT enhances differentiation and prevents overgrowth of human pluripotent stem cell-derived neural progenitors. 2018, J Biol Chem, 293, 8722-8733, PubMed ID: 29628445
Y. Hu, K. H. Fang, L. P. Shen, S. Y. Cao, F. Yuan, Y. Su, M. Xu, Y. Pan, Y. Chen and Y. Liu

hPSC-Derived Striatal Cells Generated Using a Scalable 3D Hydrogel Promote Recovery in a Huntington Disease Mouse Model. 2018, Stem Cell Reports, 10, 1481-1491, PubMed ID: 29628395
M. M. Adil, T. Gaj, A. T. Rao, R. U. Kulkarni, C. M. Fuentes, G. N. Ramadoss, F. K. Ekman, E. W. Miller and D. V. Schaffer

Direct evidence of impaired neuronal Na/K-ATPase pump function in alternating hemiplegia of childhood. 2018, Neurobiol Dis, 115, 29-38, PubMed ID: 29567111
C. Q. Simmons, C. H. Thompson, B. E. Cawthon, G. Westlake, K. J. Swoboda, E. Kiskinis, K. C. Ess and A. L. George, Jr.

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells (NPCs). 2018, J Vis Exp, PubMed ID: 29553565
M. Williams, S. Prem, X. Zhou, P. Matteson, P. L. Yeung, C. W. Lu, Z. Pang, L. Brzustowicz, J. H. Millonig and E. Dicicco-Bloom

Human Induced Pluripotent Stem Cell-Derived Sensory Neurons for Fate Commitment of Bone Marrow Stromal Cell-Derived Schwann Cells. 2018, Methods Mol Biol, 1739, 149-160, PubMed ID: 29546706
S. Cai, D. K. Y. Shum and Y. S. Chan

Highly efficient methods to obtain homogeneous dorsal neural progenitor cells from human and mouse embryonic stem cells and induced pluripotent stem cells. 2018, Stem Cell Res Ther, 9, 67, PubMed ID: 29544541
M. Zhang, J. Ngo, F. Pirozzi, Y. P. Sun and A. Wynshaw-Boris

Derivation and Identification of Motor Neurons from Human Urine-Derived Induced Pluripotent Stem Cells. 2018, Stem Cells Int, 2018, 3628578, PubMed ID: 29531534
H. Yi, B. Xie, B. Liu, X. Wang, L. Xu, J. Liu, M. Li, X. Zhong and F. Peng

Modeling Down Syndrome with Patient iPSCs Reveals Cellular and Migration Deficits of GABAergic Neurons. 2018, Stem Cell Reports, 10, 1251-1266, PubMed ID: 29526735
H. Q. Huo, Z. Y. Qu, F. Yuan, L. Ma, L. Yao, M. Xu, Y. Hu, J. Ji, A. Bhattacharyya, S. C. Zhang and Y. Liu

Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson’s disease. 2018, PLoS One, 13, e0192497, PubMed ID: 29513666
L. Marrone, C. Bus, D. Schondorf, J. C. Fitzgerald, M. Kubler, B. Schmid, P. Reinhardt, L. Reinhardt, M. Deleidi, T. Levin, A. Meixner, B. Klink, M. Glatza, C. J. Gloeckner, T. Gasser and J. Sterneckert

Down-regulation of the non-coding RNA H19 and its derived miR-675 is concomitant with up-regulation of insulin-like growth factor receptor type 1 during neural-like differentiation of human bone marrow mesenchymal stem cells. 2018, Cell Biol Int, 42, 940-948, PubMed ID: 29512257
A. Farzi-Molan, S. Babashah, B. Bakhshinejad, A. Atashi and M. Fakhr Taha

hPSC-derived Midbrain Dopaminergic Neurons Generated in a Scalable 3-D Biomaterial. 2018, Curr Protoc Stem Cell Biol, 44, 2d.21.1-2d.21.17, PubMed ID: 29512105
M. M. Adil and D. V. Schaffer

Clinical Applications of Induced Pluripotent Stem Cells – Stato Attuale. 2018, Adv Exp Med Biol, 1079, 127-149, PubMed ID: 29480445
C. Kavyasudha, D. Macrin, K. N. ArulJothi, J. P. Joseph, M. K. Harishankar and A. Devi

Central and Peripheral Nervous System Progenitors Derived from Human Pluripotent Stem Cells Reveal a Unique Temporal and Cell-Type Specific Expression of PMCAs. 2018, Front Cell Dev Biol, 6, 5, PubMed ID: 29468158
M. Chen, S. H. Laursen, M. Habekost, C. H. Knudsen, S. H. Buchholdt, J. Huang, F. Xu, X. Liu, L. Bolund, Y. Luo, P. Nissen, F. Febbraro and M. Denham

Adherent vs. Free-Floating Neural Induction by Dual SMAD Inhibition for Neurosphere Cultures Derived from Human Induced Pluripotent Stem Cells. 2018, Front Cell Dev Biol, 6, 3, PubMed ID: 29468156
M. G. Pauly, V. Krajka, F. Stengel, P. Seibler, C. Klein and P. Capetian

hiPSC-derived neural stem cells from patients with schizophrenia induce an impaired angiogenesis. 2018, Transl Psychiatry, 8, 48, PubMed ID: 29467462
B. S. Casas, G. Vitoria, M. N. do Costa, R. Madeiro da Costa, P. Trindade, R. Maciel, N. Navarrete, S. K. Rehen and V. Palma

Down-regulation of ghrelin receptors on dopaminergic neurons in the substantia nigra contributes to Parkinson’s disease-like motor dysfunction. 2018, Mol Brain, 11, 6, PubMed ID: 29458391
Y. Suda, N. Kuzumaki, T. Sone, M. Narita, K. Tanaka, Y. Hamada, C. Iwasawa, M. Shibasaki, A. Maekawa, M. Matsuo, W. Akamatsu, N. Hattori, H. Okano and M. Narita

Detection of synchronized burst firing in cultured human induced pluripotent stem cell-derived neurons using a 4-step method. 2018, Biochem Biophys Res Commun, 497, 612-618, PubMed ID: 29454965
N. Matsuda, A. Odawara, H. Katoh, N. Okuyama, R. Yokoi and I. Suzuki

Characterization of the lncRNA transcriptome in mESC-derived motor neurons: Implications for FUS-ALS. 2018, Stem Cell Res, 27, 172-179, PubMed ID: 29449089
S. Biscarini, D. Capauto, G. Peruzzi, L. Lu, A. Colantoni, T. Santini, N. A. Shneider, E. Caffarelli, P. Laneve and I. Bozzoni

Human brain organoid-on-a-chip to model prenatal nicotine exposure. 2018, Lab Chip, 18, 851-860, PubMed ID: 29437173
Y. Wang, L. Wang, Y. Zhu and J. Qin

Rotenone exerts developmental neurotoxicity in a human brain spheroid model. 2018, Toxicol Appl Pharmacol, 354, 101-114, PubMed ID: 29428530
Harris, T. Hartung and H. T. Hogberg

Characterization of calcium signals in human induced pluripotent stem cell-derived dentate gyrus neuronal progenitors and mature neurons, stably expressing an advanced calcium indicator protein. 2018, Mol Cell Neurosci, 88, 222-230, PubMed ID: 29425968
G. Vofely, T. Berecz, E. Szabo, K. Szebenyi, E. Hathy, T. I. Orban, B. Sarkadi, L. Homolya, M. C. Marchetto, J. M. Rethelyi and A. Apati

Effect of prolonged differentiation on functional maturation of human pluripotent stem cell-derived neuronal cultures. 2018, Stem Cell Res, 27, 151-161, PubMed ID: 29414606
T. Paavilainen, A. Pelkonen, M. E. Makinen, M. Peltola, H. Huhtala, D. Fayuk and S. Narkilahti

Nanotopography regulates motor neuron differentiation of human pluripotent stem cells. 2018, Nanoscale, 10, 3556-3565, PubMed ID: 29410983
W. Chen, S. Han, W. Qian, S. Weng, H. Yang, Y. Sun, L. G. Villa-Diaz, P. H. Krebsbach and J. Fu

Single-injection ex ovo transplantation method for broad spinal cord engraftment of human pluripotent stem cell-derived motor neurons. 2018, J Neurosci Methods, 298, 16-23, PubMed ID: 29408391
M. C. Estevez-Silva, A. Sreeram, S. Cuskey, N. Fedorchak, N. Iyer and R. S. Ashton

Human Neurospheroid Arrays for In Vitro Studies of Alzheimer’s Disease. 2018, Sci Rep, 8, 2450, PubMed ID: 29402979
M. Jorfi, C. D’Avanzo, R. E. Tanzi, D. Y. Kim and D. Irimia

Generation of a rod-specific NRL reporter line in human pluripotent stem cells. 2018, Sci Rep, 8, 2370, PubMed ID: 29402929
M. J. Phillips, E. E. Capowski, A. Petersen, A. D. Jansen, K. Barlow, K. L. Edwards and D. M. Gamm

Attenuation of reactive gliosis in stroke-injured mouse brain does not affect neurogenesis from grafted human iPSC-derived neural progenitors. 2018, PLoS One, 13, e0192118, PubMed ID: 29401502
C. Laterza, N. Uoshima, D. Tornero, U. Wilhelmsson, A. Stokowska, R. Ge, M. Pekny, O. Lindvall and Z. Kokaia

Astrocytes Attenuate Mitochondrial Dysfunctions in Human Dopaminergic Neurons Derived from iPSC. 2018, Stem Cell Reports, 10, 366-374, PubMed ID: 29396183
F. Du, Q. Yu, A. Chen, D. Chen and S. S. Yan

Effect of leukocyte inhibitory factor on neuron differentiation from human induced pluripotent stem cell-derived neural precursor cells. 2018, Int J Mol Med, 41, 2037-2049, PubMed ID: 29393372
L. Xu, J. Long, C. Shi, N. Zhang, Y. Lv, J. Feng, A. Xuan, X. He, Q. Li, Y. Bai, S. Liu and D. Long

Culture Systems of Dissociated Mouse and Human Pluripotent Stem Cell-Derived Retinal Ganglion Cells Purified by Two-Step Immunopanning. 2018, Invest Ophthalmol Vis Sci, 59, 776-787, PubMed ID: 29392326
W. Kobayashi, A. Onishi, H. Y. Tu, Y. Takihara, M. Matsumura, K. Tsujimoto, M. Inatani, T. Nakazawa and M. Takahashi

Antagonism between the transcription factors NANOG and OTX2 specifies rostral or caudal cell fate during neural patterning transition. 2018, J Biol Chem, 293, 4445-4455, PubMed ID: 29386354
Z. Su, Y. Zhang, B. Liao, X. Zhong, X. Chen, H. Wang, Y. Guo, Y. Shan, L. Wang and G. Pan

Generation of Isthmic Organizer-Like Cells from Human Embryonic Stem Cells. 2018, Mol Cells, 41, 110-118, PubMed ID: 29385674
J. Lee, S. H. Choi, D. R. Lee, D. S. Kim and D. W. Kim

A novel human induced pluripotent stem cell blood-brain barrier model: Applicability to study antibody-triggered receptor-mediated transcytosis. 2018, Sci Rep, 8, 1873, PubMed ID: 29382846
M. Ribecco-Lutkiewicz, C. Sodja, J. Haukenfrers, A. S. Haqqani, D. Ly, P. Zachar, E. Baumann, M. Ball, J. Huang, M. Rukhlova, M. Martina, Q. Liu, D. Stanimirovic, A. Jezierski and M. Bani-Yaghoub

Fabrication of Hemin-Doped Serum Albumin-Based Fibrous Scaffolds for Neural Tissue Engineering Applications. 2018, ACS Appl Mater Interfaces, 10, 5305-5317, PubMed ID: 29381329
C. C. Hsu, A. Serio, N. Amdursky, C. Besnard and M. M. Stevens

Chromosomal instability during neurogenesis in Huntington’s disease. 2018, Development, 145, PubMed ID: 29378824
A. Ruzo, G. F. Croft, J. J. Metzger, S. Galgoczi, L. J. Gerber, C. Pellegrini, H. Wang, Jr., M. Fenner, S. Tse, A. Marks, C. Nchako and A. H. Brivanlou

NaV1.7 as a Pharmacogenomic Target for Pain: Moving Toward Precision Medicine. 2018, Trends Pharmacol Sci, 39, 258-275, PubMed ID: 29370938
Y. Yang, M. A. Mis, M. Estacion, S. D. Dib-Hajj and S. G. Waxman

Guggulsterone-releasing microspheres direct the differentiation of human induced pluripotent stem cells into neural phenotypes. 2018, Biomed Mater, 13, 034104, PubMed ID: 29368696
A. Agbay, L. De La Vega, G. Nixon and S. Willerth

Bioactivity and gene expression profiles of hiPSC-generated retinal ganglion cells in MT-ND4 mutated Leber’s hereditary optic neuropathy. 2018, Exp Cell Res, 363, 299-309, PubMed ID: 29366807
Y. R. Wu, A. G. Wang, Y. T. Chen, A. A. Yarmishyn, W. Buddhakosai, T. C. Yang, D. K. Hwang, Y. P. Yang, C. N. Shen, H. C. Lee, S. H. Chiou, C. H. Peng and S. J. Chen

The rise of three-dimensional human brain cultures. 2018, Nature, 553, 437-445, PubMed ID: 29364288
S. P. Pasca

Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation. 2018, Nat Commun, 9, 335, PubMed ID: 29362359
M. Naumann, A. Pal, A. Goswami, X. Lojewski, J. Japtok, A. Vehlow, M. Naujock, R. Gunther, M. Jin, N. Stanslowsky, P. Reinhardt, J. Sterneckert, M. Frickenhaus, F. Pan-Montojo, E. Storkebaum, I. Poser, A. Freischmidt, J. H. Weishaupt, K. Holzmann, D. Troost, A. C. Ludolph, T. M. Boeckers, S. Liebau, S. Petri, N. Cordes, A. A. Hyman, F. Wegner, S. W. Grill, J. Weis, A. Storch and A. Hermann

Using intracellular markers to identify a novel set of surface markers for live cell purification from a heterogeneous hIPSC culture. 2018, Sci Rep, 8, 804, PubMed ID: 29339826
E. J. Paik, A. L. O’Neil, S. Y. Ng, C. Sun and L. L. Rubin

Deriving Dorsal Spinal Sensory Interneurons from Human Pluripotent Stem Cells. 2018, Stem Cell Reports, 10, 390-405, PubMed ID: 29337120
S. Gupta, D. Sivalingam, S. Hain, C. Makkar, E. Sosa, A. Clark and S. J. Butler

Development and disease in a dish: the epigenetics of neurodevelopmental disorders. 2018, Epigenomics, 10, 219-231, PubMed ID: 29334242
E. M. Lewis and K. L. Kroll

Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells. 2018, Sci Rep, 8, 603, PubMed ID: 29330377
A. J. Alshawaf, S. Viventi, W. Qiu, G. D’Abaco, B. Nayagam, M. Erlichster, G. Chana, I. Everall, J. Ivanusic, E. Skafidas and M. Dottori

Allele-Specific Biased Expression of the CNTN6 Gene in iPS Cell-Derived Neurons from a Patient with Intellectual Disability and 3p26.3 Microduplication Involving the CNTN6 Gene. 2018, Mol Neurobiol, 55, 6533-6546, PubMed ID: 29327201
M. M. Gridina, N. M. Matveeva, V. S. Fishman, A. G. Menzorov, H. A. Kizilova, N. A. Beregovoy, Kovrigin, II, I. E. Pristyazhnyuk, I. P. Oscorbin, M. L. Filipenko, A. A. Kashevarova, N. A. Skryabin, T. V. Nikitina, E. A. Sazhenova, L. P. Nazarenko, I. N. Lebedev and O. L. Serov

BMP/SMAD Pathway Promotes Neurogenesis of Midbrain Dopaminergic Neurons In Vivo and in Human Induced Pluripotent and Neural Stem Cells. 2018, J Neurosci, 38, 1662-1676, PubMed ID: 29321139
V. M. Jovanovic, A. Salti, H. Tilleman, K. Zega, M. M. Jukic, H. Zou, R. H. Friedel, N. Prakash, S. Blaess, F. Edenhofer and C. Brodski

Function of FEZF1 during early neural differentiation of human embryonic stem cells. 2018, Sci China Life Sci, 61, 35-45, PubMed ID: 29318501
X. Liu, P. Su, L. Lu, Z. Feng, H. Wang and J. Zhou

Reproducible and efficient generation of functionally active neurons from human hiPSCs for preclinical disease modeling. 2018, Stem Cell Res, 26, 84-94, PubMed ID: 29272856
Y. Xie, R. J. Schutte, N. N. Ng, K. C. Ess, P. H. Schwartz and D. K. O’Dowd

Neonatal mouse cortical but not isogenic human astrocyte feeder layers enhance the functional maturation of induced pluripotent stem cell-derived neurons in culture. 2018, Glia, 66, 725-748, PubMed ID: 29230877
F. W. Lischka, A. Efthymiou, Q. Zhou, M. D. Nieves, N. M. McCormack, M. D. Wilkerson, G. Sukumar, C. L. Dalgard and M. L. Doughty

Comparative analysis of human embryonic stem cellderived neural stem cells as an in vitro human model. 2018, Int J Mol Med, 41, 783-790, PubMed ID: 29207026
J. H. Oh, C. R. Jung, M. O. Lee, J. Kim and M. Y. Son

Neural stem cells: developmental mechanisms and disease modeling. 2018, Cell Tissue Res, 371, 1-6, PubMed ID: 29196810
X. Zhao and D. L. Moore

Single-cell analysis of diversity in human stem cell-derived neurons. 2018, Cell Tissue Res, 371, 171-179, PubMed ID: 29185070
L. J. Harbom, N. Michel and M. J. McConnell

Temporally coordinated spiking activity of human induced pluripotent stem cell-derived neurons co-cultured with astrocytes. 2018, Biochem Biophys Res Commun, 495, 1028-1033, PubMed ID: 29170135
T. Kayama, I. Suzuki, A. Odawara, T. Sasaki and Y. Ikegaya

Patient-derived iPSCs show premature neural differentiation and neuron type-specific phenotypes relevant to neurodevelopment. 2018, Mol Psychiatry, 23, 1687-1698, PubMed ID: 29158583
E. Yeh, D. Q. Dao, Z. Y. Wu, S. M. Kandalam, F. M. Camacho, C. Tom, W. Zhang, R. Krencik, K. A. Rauen, E. M. Ullian and L. A. Weiss

Human dental stem cell derived transgene-free iPSCs generate functional neurons via embryoid body-mediated and direct induction methods. 2018, J Tissue Eng Regen Med, 12, e1836-e1851, PubMed ID: 29139614
I. El Ayachi, J. Zhang, X. Y. Zou, D. Li, Z. Yu, W. Wei, K. M. S. O’Connell and G. T. Huang

Mechanisms of dietary flavonoid action in neuronal function and neuroinflammation. 2018, Mol Aspects Med, 61, 50-62, PubMed ID: 29117513
B. N. Jaeger, S. L. Parylak and F. H. Gage

Transplantation of feeder-free human induced pluripotent stem cell-derived cortical neuron progenitors in adult male Wistar rats with focal brain ischemia. 2018, J Neurosci Res, 96, 863-874, PubMed ID: 29110329
Y. Hermanto, T. Sunohara, A. Faried, Y. Takagi, J. Takahashi, T. Maki and S. Miyamoto

Copine1 regulates neural stem cell functions during brain development. 2018, Biochem Biophys Res Commun, 495, 168-173, PubMed ID: 29101038
T. H. Kim, S. E. Sung, J. Cheal Yoo, J. Y. Park, G. S. Yi, J. Y. Heo, J. R. Lee, N. S. Kim and D. Y. Lee

Combined delivery of chondroitinase ABC and human induced pluripotent stem cell-derived neuroepithelial cells promote tissue repair in an animal model of spinal cord injury. 2018, Biomed Mater, 13, 024103, PubMed ID: 29083317
T. Fuhrmann, P. N. Anandakumaran, S. L. Payne, M. M. Pakulska, B. V. Varga, A. Nagy, C. Tator and M. S. Shoichet

Modeling neurological diseases using iPSC-derived neural cells : iPSC modeling of neurological diseases. 2018, Cell Tissue Res, 371, 143-151, PubMed ID: 29079884
L. Li, J. Chao and Y. Shi

Mouse Parthenogenetic Embryonic Stem Cells with Biparental-Like Expression of Imprinted Genes Generate Cortical-Like Neurons That Integrate into the Injured Adult Cerebral Cortex. 2018, Stem Cells, 36, 192-205, PubMed ID: 29044892
A. Varrault, S. Eckardt, B. Girard, A. Le Digarcher, I. Sassetti, C. Meusnier, C. Ripoll, A. Badalyan, F. Bertaso, K. J. McLaughlin, L. Journot and T. Bouschet

In vitro segregation and isolation of human pluripotent stem cell-derived neural crest cells. 2018, Methods, 133, 65-80, PubMed ID: 29037816
S. Munst, P. Koch, J. Kesavan, M. Alexander-Mays, B. Munst, S. Blaess and O. Brustle

Electrophysiological investigation of human embryonic stem cell derived neurospheres using a novel spike detection algorithm. 2018, Biosens Bioelectron, 100, 462-468, PubMed ID: 28963963
M. Mayer, O. Arrizabalaga, F. Lieb, M. Ciba, S. Ritter and C. Thielemann

Activation of RARalpha, RARgamma, or RXRalpha Increases Barrier Tightness in Human Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells. 2018, Biotechnol J, 13, PubMed ID: 28960887
M. J. Stebbins, E. S. Lippmann, M. G. Faubion, R. Daneman, S. P. Palecek and E. V. Shusta

Stem cell transplantation for Huntington’s diseases. 2018, Methods, 133, 104-112, PubMed ID: 28867501
K. A. Choi, Y. Choi and S. Hong

Neural stem cells and epilepsy: functional roles and disease-in-a-dish models. 2018, Cell Tissue Res, 371, 47-54, PubMed ID: 28831605
D. M. Thodeson, R. Brulet and J. Hsieh

Method of derivation and differentiation of mouse embryonic stem cells generating synchronous neuronal networks. 2018, J Neurosci Methods, 293, 53-58, PubMed ID: 28827162
E. V. Gazina, E. Morrisroe, G. D. C. Mendis, A. E. Michalska, J. Chen, C. M. Nefzger, B. N. Rollo, C. A. Reid, M. F. Pera and S. Petrou

Markers associated with neuron-specific Ube3a imprinting during neuronal differentiation of mouse embryonic stem cells. 2018, Cytotechnology, 70, 45-53, PubMed ID: 28780625
M. Eitoku, H. Kato, N. Suganuma and H. Kiyosawa

Astrocyte-enriched feeder layers from cryopreserved cells support differentiation of spontaneously active networks of human iPSC-derived neurons. 2018, J Neurosci Methods, 294, 91-101, PubMed ID: 28746822
R. J. Schutte, Y. Xie, N. N. Ng, P. Figueroa, A. T. Pham and D. K. O’Dowd

DNA methylation and copy number variation analyses of human embryonic stem cell-derived neuroprogenitors after low-dose decabromodiphenyl ether and/or bisphenol A exposure. 2018, Hum Exp Toxicol, 37, 475-485, PubMed ID: 28597690
L. Du, W. Sun, X. M. Li, X. Y. Li, W. Liu and D. Chen

In Vitro Maturation of Human iPSC-Derived Neuroepithelial Cells Influences Transplant Survival in the Stroke-Injured Rat Brain. 2018, Tissue Eng Part A, 24, 351-360, PubMed ID: 28594288
S. L. Payne, P. N. Anandakumaran, B. V. Varga, C. M. Morshead, A. Nagy and M. S. Shoichet

Isolated Mitochondria Transfer Improves Neuronal Differentiation of Schizophrenia-Derived Induced Pluripotent Stem Cells and Rescues Deficits in a Rat Model of the Disorder. 2018, Schizophr Bull, 44, 432-442, PubMed ID: 28586483
O. Robicsek, H. M. Ene, R. Karry, O. Ytzhaki, E. Asor, D. McPhie, B. M. Cohen, R. Ben-Yehuda, I. Weiner and D. Ben-Shachar

A simplified protocol for differentiation of electrophysiologically mature neuronal networks from human induced pluripotent stem cells. 2018, Mol Psychiatry, 23, 1336-1344, PubMed ID: 28416807
N. Gunhanlar, G. Shpak, M. van der Kroeg, L. A. Gouty-Colomer, S. T. Munshi, B. Lendemeijer, M. Ghazvini, C. Dupont, W. J. G. Hoogendijk, J. Gribnau, F. M. S. de Vrij and S. A. Kushner

Sphingosine-1-Phosphate (S1P) Signaling in Neural Progenitors. 2018, Methods Mol Biol, 1697, 141-151, PubMed ID: 28361481
P. Callihan, M. Alqinyah and S. B. Hooks

miR-124 and miR-9 mediated downregulation of HDAC5 promotes neurite development through activating MEF2C-GPM6A pathway. 2018, J Cell Physiol, 233, 673-687, PubMed ID: 28332716
X. Gu, C. Fu, L. Lin, S. Liu, X. Su, A. Li, Q. Wu, C. Jia, P. Zhang, L. Chen, X. Zhu and X. Wang

Direct Conversion of Somatic Cells into Induced Neurons. 2018, Mol Neurobiol, 55, 642-651, PubMed ID: 27981499
N. An, H. Xu, W. Q. Gao and H. Yang

LRRK2 Expression Is Deregulated in Fibroblasts and Neurons from Parkinson Patients with Mutations in PINK1. 2018, Mol Neurobiol, 55, 506-516, PubMed ID: 27975167
G. Azkona, R. Lopez de Maturana, P. Del Rio, A. Sousa, N. Vazquez, A. Zubiarrain, D. Jimenez-Blasco, J. P. Bolanos, B. Morales, G. Auburger, J. M. Arbelo and R. Sanchez-Pernaute

Characterization and transplantation of enteric neural crest cells from human induced pluripotent stem cells. 2018, Mol Psychiatry, 23, 499-508, PubMed ID: 27777423
W. Li, L. Huang, J. Zeng, W. Lin, K. Li, J. Sun, W. Huang, J. Chen, G. Wang, Q. Ke, J. Duan, X. Lai, R. Chen, M. Liu, Y. Liu, T. Wang, X. Yang, Y. Chen, H. Xia and A. P. Xiang

[Expression difference of connexins in neural cells of Cx26 deficiency deafness]. 2017, Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi, 31, 1579-1584, PubMed ID: 29797954
X. F. Jin, W. W. Zhu, H. Yang and Z. Q. Gao

Defined Culture Conditions Accelerate Small-molecule-assisted Neural Induction for the Production of Neural Progenitors from Human-induced Pluripotent Stem Cells. 2017, Cell Transplant, 26, 1890-1902, PubMed ID: 29390875
P. Walsh, V. Truong, C. Hill, N. D. Stoflet, J. Baden, W. C. Low, S. A. Keirstead, J. R. Dutton and A. M. Parr

Temporal Progression of Retinal Progenitor Cell Identity: Implications in Cell Replacement Therapies. 2017, Front Neural Circuits, 11, 105, PubMed ID: 29375321
A. Javed and M. Cayouette

Induced pluripotent stem cells in modeling and cell-based therapy of amyotrophic lateral sclerosis. 2017, J Physiol Pharmacol, 68, 649-657, PubMed ID: 29375039
M. Csobonyeiova, S. Polak, A. Nicodemou and L. Danisovic

An intermediate cell state allows rerouting of cell fate. 2017, J Biol Chem, 292, 19133-19134, PubMed ID: 29373866
X. Wang and J. Li

Current Advances and Limitations in Modeling ALS/FTD in a Dish Using Induced Pluripotent Stem Cells. 2017, Front Neurosci, 11, 671, PubMed ID: 29326542
W. Guo, L. Fumagalli, R. Prior and L. Van Den Bosch

Streamlined 3D Cerebellar Differentiation Protocol with Optional 2D Modification. 2017, J Vis Exp, PubMed ID: 29286492
D. B. Holmes and V. M. Heine

Differentiation of Mouse Embryonic Stem Cells into Cortical Interneuron Precursors. 2017, J Vis Exp, PubMed ID: 29286389
D. J. Tischfield and S. A. Anderson

Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains. 2017, Nat Commun, 8, 2225, PubMed ID: 29263384
G. E. Hoffman, B. J. Hartley, E. Flaherty, I. Ladran, P. Gochman, D. M. Ruderfer, E. A. Stahl, J. Rapoport, P. Sklar and K. J. Brennand

Using Human iPSC-Derived Neurons to Uncover Activity-Dependent Non-Coding RNAs. 2017, Genes (Basel), 8, PubMed ID: 29261115
M. Bitar, S. Kuiper, E. O’Brien and G. Barry

Novel schizophrenia risk factor pathways regulate FEZ1 to advance oligodendroglia development. 2017, Transl Psychiatry, 7, 1293, PubMed ID: 29249816
X. Chen, L. Ku, R. Mei, G. Liu, C. Xu, Z. Wen, X. Zhao, F. Wang, L. Xiao and Y. Feng

Genetically unmatched human iPSC and ESC exhibit equivalent gene expression and neuronal differentiation potential. 2017, Sci Rep, 7, 17504, PubMed ID: 29235536
H. E. Marei, A. Althani, S. Lashen, C. Cenciarelli and A. Hasan

Regulatory networks specifying cortical interneurons from human embryonic stem cells reveal roles for CHD2 in interneuron development. 2017, Proc Natl Acad Sci U S A, 114, E11180-e11189, PubMed ID: 29229852
K. Meganathan, E. M. A. Lewis, P. Gontarz, S. Liu, E. G. Stanley, A. G. Elefanty, J. E. Huettner, B. Zhang and K. L. Kroll

[Neural differentiation from induced pluripotent stem cells for disease modelling and drug discovery]. 2017, Nihon Yakurigaku Zasshi, 150, 282-285, PubMed ID: 29225290
W. Akamatsu

Cellular Phenotypes in Human iPSC-Derived Neurons from a Genetic Model of Autism Spectrum Disorder. 2017, Cell Rep, 21, 2678-2687, PubMed ID: 29212016
A. Deshpande, S. Yadav, D. Q. Dao, Z. Y. Wu, K. C. Hokanson, M. K. Cahill, A. P. Wiita, Y. N. Jan, E. M. Ullian and L. A. Weiss

Altered Differentiation Potential of Gaucher’s Disease iPSC Neuronal Progenitors due to Wnt/beta-Catenin Downregulation. 2017, Stem Cell Reports, 9, 1853-1867, PubMed ID: 29198828
O. Awad, L. M. Panicker, R. M. Deranieh, M. P. Srikanth, R. A. Brown, A. Voit, T. Peesay, T. S. Park, E. T. Zambidis and R. A. Feldman

Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes. 2017, Stem Cell Reports, 9, 1745-1753, PubMed ID: 29198827
R. Krencik, K. Seo, J. V. van Asperen, N. Basu, C. Cvetkovic, S. Barlas, R. Chen, C. Ludwig, C. Wang, M. E. Ward, L. Gan, P. J. Horner, D. H. Rowitch and E. M. Ullian

Neurons derived from sporadic Alzheimer’s disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation. 2017, Alzheimers Res Ther, 9, 90, PubMed ID: 29191219
A. Ochalek, B. Mihalik, H. X. Avci, A. Chandrasekaran, A. Teglasi, I. Bock, M. L. Giudice, Z. Tancos, K. Molnar, L. Laszlo, J. E. Nielsen, B. Holst, K. Freude, P. Hyttel, J. Kobolak and A. Dinnyes

Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming. 2017, Cell Stem Cell, 21, 791-805.e9, PubMed ID: 29174331
T. Ruetz, U. Pfisterer, B. Di Stefano, J. Ashmore, M. Beniazza, T. V. Tian, D. F. Kaemena, L. Tosti, W. Tan, J. R. Manning, E. Chantzoura, D. R. Ottosson, S. Collombet, A. Johnsson, E. Cohen, K. Yusa, S. Linnarsson, T. Graf, M. Parmar and K. Kaji

Probing impaired neurogenesis in human brain organoids exposed to alcohol. 2017, Integr Biol (Camb), 9, 968-978, PubMed ID: 29168871
Y. Zhu, L. Wang, F. Yin, Y. Yu, Y. Wang, M. J. Shepard, Z. Zhuang and J. Qin

Specification of murine ground state pluripotent stem cells to regional neuronal populations. 2017, Sci Rep, 7, 16001, PubMed ID: 29167563
W. F. Alsanie, J. C. Niclis, C. P. Hunt, I. R. De Luzy, V. Penna, C. R. Bye, C. W. Pouton, J. Haynes, J. Firas, L. H. Thompson and C. L. Parish

Generation of patient specific human neural stem cells from Niemann-Pick disease type C patient-derived fibroblasts. 2017, Oncotarget, 8, 85428-85441, PubMed ID: 29156730
E. A. Sung, K. R. Yu, J. H. Shin, Y. Seo, H. S. Kim, M. G. Koog, I. Kang, J. J. Kim, B. C. Lee, T. H. Shin, J. Y. Lee, S. Lee, T. W. Kang, S. W. Choi and K. S. Kang

Cell-type Dependent Alzheimer’s Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability. 2017, Stem Cell Reports, 9, 1868-1884, PubMed ID: 29153990
C. R. Muratore, C. Zhou, M. Liao, M. A. Fernandez, W. M. Taylor, V. N. Lagomarsino, R. V. Pearse, 2nd, H. C. Rice, J. M. Negri, A. He, P. Srikanth, D. G. Callahan, T. Shin, M. Zhou, D. A. Bennett, S. Noggle, J. C. Love, D. J. Selkoe and T. L. Young-Pearse

Isolation and Comparative Transcriptome Analysis of Human Fetal and iPSC-Derived Cone Photoreceptor Cells. 2017, Stem Cell Reports, 9, 1898-1915, PubMed ID: 29153988
E. Welby, J. Lakowski, V. Di Foggia, D. Budinger, A. Gonzalez-Cordero, A. T. L. Lun, M. Epstein, A. Patel, E. Cuevas, K. Kruczek, A. Naeem, F. Minneci, M. Hubank, D. T. Jones, J. C. Marioni, R. R. Ali and J. C. Sowden

A post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells. 2017, Nat Commun, 8, 1456, PubMed ID: 29129916
H. Ju Lee, D. Bartsch, C. Xiao, S. Guerrero, G. Ahuja, C. Schindler, J. J. Moresco, J. R. Yates, 3rd, F. Gebauer, H. Bazzi, C. Dieterich, L. Kurian and D. Vilchez

Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells. 2017, Stem Cell Res, 25, 139-151, PubMed ID: 29128818
A. Chandrasekaran, H. X. Avci, A. Ochalek, L. N. Rosingh, K. Molnar, L. Laszlo, T. Bellak, A. Teglasi, K. Pesti, A. Mike, P. Phanthong, O. Biro, V. Hall, N. Kitiyanant, K. H. Krause, J. Kobolak and A. Dinnyes

Unraveling the biology of bipolar disorder using induced pluripotent stem-derived neurons. 2017, Bipolar Disord, 19, 544-551, PubMed ID: 29116664
N. D. Miller and J. R. Kelsoe

Cell Therapy for Parkinson’s Disease. 2017, Cell Transplant, 26, 1551-1559, PubMed ID: 29113472
T. Yasuhara, M. Kameda, T. Sasaki, N. Tajiri and I. Date

Comparative performance analysis of human iPSC-derived and primary neural progenitor cells (NPC) grown as neurospheres in vitro. 2017, Stem Cell Res, 25, 72-82, PubMed ID: 29112887
M. Hofrichter, L. Nimtz, J. Tigges, Y. Kabiri, F. Schroter, B. Royer-Pokora, B. Hildebrandt, M. Schmuck, A. Epanchintsev, S. Theiss, J. Adjaye, J. M. Egly, J. Krutmann and E. Fritsche

Overcoming Monocarboxylate Transporter 8 (MCT8)-Deficiency to Promote Human Oligodendrocyte Differentiation and Myelination. 2017, EBioMedicine, 25, 122-135, PubMed ID: 29111262
J. Y. Lee, M. J. Kim, D. Deliyanti, M. F. Azari, F. Rossello, A. Costin, G. Ramm, E. G. Stanley, A. G. Elefanty, J. L. Wilkinson-Berka and S. Petratos

Default Patterning Produces Pan-cortical Glutamatergic and CGE/LGE-like GABAergic Neurons from Human Pluripotent Stem Cells. 2017, Stem Cell Reports, 9, 1463-1476, PubMed ID: 29107596
C. M. Floruta, R. Du, H. Kang, J. L. Stein and J. P. Weick

Escape from Pluripotency via Inhibition of TGF-beta/BMP and Activation of Wnt Signaling Accelerates Differentiation and Aging in hPSC Progeny Cells. 2017, Stem Cell Reports, 9, 1675-1691, PubMed ID: 29107593
K. Fujimori, T. Matsumoto, F. Kisa, N. Hattori, H. Okano and W. Akamatsu

Generation of a Motor Nerve Organoid with Human Stem Cell-Derived Neurons. 2017, Stem Cell Reports, 9, 1441-1449, PubMed ID: 29107592
J. Kawada, S. Kaneda, T. Kirihara, A. Maroof, T. Levi, K. Eggan, T. Fujii and Y. Ikeuchi

Comparative Analysis of AGE and RAGE Levels in Human Somatic and Embryonic Stem Cells under H2O2-Induced Noncytotoxic Oxidative Stress Conditions. 2017, Oxid Med Cell Longev, 2017, 4240136, PubMed ID: 29104727
M. Barandalla, E. Haucke, B. Fischer, A. Navarrete Santos, S. Colleoni, C. Galli, A. Navarrete Santos and G. Lazzari

DISC1 Regulates Neurogenesis via Modulating Kinetochore Attachment of Ndel1/Nde1 during Mitosis. 2017, Neuron, 96, 1041-1054.e5, PubMed ID: 29103808
F. Ye, E. Kang, C. Yu, X. Qian, F. Jacob, C. Yu, M. Mao, R. Y. C. Poon, J. Kim, H. Song, G. L. Ming and M. Zhang

Bundle Gel Fibers with a Tunable Microenvironment for in Vitro Neuron Cell Guiding. 2017, ACS Appl Mater Interfaces, 9, 43250-43257, PubMed ID: 29086563
S. Tachizawa, H. Takahashi, Y. J. Kim, A. Odawara, J. Pauty, Y. Ikeuchi, I. Suzuki, A. Kikuchi and Y. T. Matsunaga

Human iPSC-Derived Cerebellar Neurons from a Patient with Ataxia-Telangiectasia Reveal Disrupted Gene Regulatory Networks. 2017, Front Cell Neurosci, 11, 321, PubMed ID: 29081736
S. P. Nayler, J. E. Powell, D. P. Vanichkina, O. Korn, C. A. Wells, R. Kanjhan, J. Sun, R. J. Taft, M. F. Lavin and E. J. Wolvetang

CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer’s PSEN2 (N141I) neurons. 2017, Acta Neuropathol Commun, 5, 77, PubMed ID: 29078805
M. Ortiz-Virumbrales, C. L. Moreno, I. Kruglikov, P. Marazuela, A. Sproul, S. Jacob, M. Zimmer, D. Paull, B. Zhang, E. E. Schadt, M. E. Ehrlich, R. E. Tanzi, O. Arancio, S. Noggle and S. Gandy

Modeling the behavior of human induced pluripotent stem cells seeded on melt electrospun scaffolds. 2017, J Biol Eng, 11, 38, PubMed ID: 29075321
M. E. Hall, N. K. Mohtaram, S. M. Willerth and R. Edwards

Generation and Characterization of Functional Human Hypothalamic Neurons. 2017, Curr Protoc Neurosci, 81, 3.33.1-3.33.24, PubMed ID: 29064566
P. Kirwan, M. Jura and F. T. Merkle

Recapitulating cortical development with organoid culture in vitro and modeling abnormal spindle-like (ASPM related primary) microcephaly disease. 2017, Protein Cell, 8, 823-833, PubMed ID: 29058117
R. Li, L. Sun, A. Fang, P. Li, Q. Wu and X. Wang

The L1 adhesion molecule normalizes neuritogenesis in Rett syndrome-derived neural precursor cells. 2017, Biochem Biophys Res Commun, 494, 504-510, PubMed ID: 29050935
M. Yoo, C. Carromeu, O. Kwon, A. Muotri and M. Schachner

GSK-J4-Mediated Transcriptomic Alterations in Differentiating Embryoid Bodies. 2017, Mol Cells, 40, 737-751, PubMed ID: 29047260
C. Mandal, S. H. Kim, S. C. Kang, J. C. Chai, Y. S. Lee, K. H. Jung and Y. G. Chai

PeakCaller: an automated graphical interface for the quantification of intracellular calcium obtained by high-content screening. 2017, BMC Neurosci, 18, 72, PubMed ID: 29037171
E. Artimovich, R. K. Jackson, M. B. C. Kilander, Y. C. Lin and M. W. Nestor

Neurotrophic support by traumatized muscle-derived multipotent progenitor cells: Role of endothelial cells and Vascular Endothelial Growth Factor-A. 2017, Stem Cell Res Ther, 8, 226, PubMed ID: 29029631
H. R. H. Zupanc, P. G. Alexander and R. S. Tuan

Current progress in the derivation and therapeutic application of neural stem cells. 2017, Cell Death Dis, 8, e3108, PubMed ID: 29022921
Y. Tang, P. Yu and L. Cheng

Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection. 2017, Cell Rep, 21, 517-532, PubMed ID: 29020636
M. Watanabe, J. E. Buth, N. Vishlaghi, L. de la Torre-Ubieta, J. Taxidis, B. S. Khakh, G. Coppola, C. A. Pearson, K. Yamauchi, D. Gong, X. Dai, R. Damoiseaux, R. Aliyari, S. Liebscher, K. Schenke-Layland, C. Caneda, E. J. Huang, Y. Zhang, G. Cheng, D. H. Geschwind, P. Golshani, R. Sun and B. G. Novitch

A Scaled Framework for CRISPR Editing of Human Pluripotent Stem Cells to Study Psychiatric Disease. 2017, Stem Cell Reports, 9, 1315-1327, PubMed ID: 29020615
D. Z. Hazelbaker, A. Beccard, A. M. Bara, N. Dabkowski, A. Messana, P. Mazzucato, D. Lam, D. Manning, K. Eggan and L. E. Barrett

FUS Mutant Human Motoneurons Display Altered Transcriptome and microRNA Pathways with Implications for ALS Pathogenesis. 2017, Stem Cell Reports, 9, 1450-1462, PubMed ID: 28988989
R. De Santis, L. Santini, A. Colantoni, G. Peruzzi, V. de Turris, V. Alfano, I. Bozzoni and A. Rosa

Semagacestat Is a Pseudo-Inhibitor of gamma-Secretase. 2017, Cell Rep, 21, 259-273, PubMed ID: 28978478
S. Tagami, K. Yanagida, T. S. Kodama, M. Takami, N. Mizuta, H. Oyama, K. Nishitomi, Y. W. Chiu, T. Okamoto, T. Ikeuchi, G. Sakaguchi, T. Kudo, Y. Matsuura, A. Fukumori, M. Takeda, Y. Ihara and M. Okochi

FOXOs modulate proteasome activity in human-induced pluripotent stem cells of Huntington’s disease and their derived neural cells. 2017, Hum Mol Genet, 26, 4416-4428, PubMed ID: 28973411
Y. Liu, F. Qiao, P. C. Leiferman, A. Ross, E. H. Schlenker and H. Wang

Transcriptome analysis reveals determinant stages controlling human embryonic stem cell commitment to neuronal cells. 2017, J Biol Chem, 292, 19590-19604, PubMed ID: 28972157
Y. Li, R. Wang, N. Qiao, G. Peng, K. Zhang, K. Tang, J. J. Han and N. Jing

Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening. 2017, Stem Cell Reports, 9, 1221-1233, PubMed ID: 28966121
C. Wang, M. E. Ward, R. Chen, K. Liu, T. E. Tracy, X. Chen, M. Xie, P. D. Sohn, C. Ludwig, A. Meyer-Franke, C. M. Karch, S. Ding and L. Gan

Direct conversion of human fibroblasts to functional excitatory cortical neurons integrating into human neural networks. 2017, Stem Cell Res Ther, 8, 207, PubMed ID: 28962665
G. Miskinyte, K. Devaraju, M. Gronning Hansen, E. Monni, D. Tornero, N. B. Woods, J. Bengzon, H. Ahlenius, O. Lindvall and Z. Kokaia

Lineage- and developmental stage-specific mechanomodulation of induced pluripotent stem cell differentiation. 2017, Stem Cell Res Ther, 8, 216, PubMed ID: 28962663
M. Maldonado, R. J. Luu, G. Ico, A. Ospina, D. Myung, H. P. Shih and J. Nam

From the Cover: Manganese and Rotenone-Induced Oxidative Stress Signatures Differ in iPSC-Derived Human Dopamine Neurons. 2017, Toxicol Sci, 159, 366-379, PubMed ID: 28962525
M. D. Neely, C. A. Davison, M. Aschner and A. B. Bowman

Primary Spinal OPC Culture System from Adult Zebrafish to Study Oligodendrocyte Differentiation In Vitro. 2017, Front Cell Neurosci, 11, 284, PubMed ID: 28959189
V. Kroehne, V. Tsata, L. Marrone, C. Froeb, S. Reinhardt, A. Gompf, A. Dahl, J. Sterneckert and M. M. Reimer

Immuno-detection of cleaved SNAP-25 from differentiated mouse embryonic stem cells provides a sensitive assay for determination of botulinum A toxin and antitoxin potency. 2017, J Immunol Methods, 451, 90-99, PubMed ID: 28943257
G. Yadirgi, P. Stickings, S. Rajagopal, Y. Liu and D. Sesardic

IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells. 2017, Stem Cell Reports, 9, 1207-1220, PubMed ID: 28943253
D. Lehnen, S. Barral, T. Cardoso, S. Grealish, A. Heuer, A. Smiyakin, A. Kirkeby, J. Kollet, H. Cremer, M. Parmar, A. Bosio and S. Knobel

Elongation of Axon Extension for Human iPSC-Derived Retinal Ganglion Cells by a Nano-Imprinted Scaffold. 2017, Int J Mol Sci, 18, PubMed ID: 28930148
T. C. Yang, J. H. Chuang, W. Buddhakosai, W. J. Wu, C. J. Lee, W. S. Chen, Y. P. Yang, M. C. Li, C. H. Peng and S. J. Chen

One-Step piggyBac Transposon-Based CRISPR/Cas9 Activation of Multiple Genes. 2017, Mol Ther Nucleic Acids, 8, 64-76, PubMed ID: 28918057
S. Li, A. Zhang, H. Xue, D. Li and Y. Liu

Effects of short-term exposure to sevoflurane on the survival, proliferation, apoptosis, and differentiation of neural precursor cells derived from human embryonic stem cells. 2017, J Anesth, 31, 821-828, PubMed ID: 28913662
J. W. Park, M. S. Lim, S. Y. Ji, M. S. Cho, S. J. Park, S. H. Han and J. H. Kim

Neuronal Cell Sheets of Cortical Motor Neuron Phenotype Derived from Human iPSCs. 2017, Cell Transplant, 26, 1355-1364, PubMed ID: 28901192
N. Suzuki, N. Arimitsu, J. Shimizu, K. Takai, C. Hirotsu, Y. Ueda, S. Wakisaka, N. Fujiwara and T. Suzuki

CRISPR-Cas9-based photoactivatable transcription systems to induce neuronal differentiation. 2017, Nat Methods, 14, 963-966, PubMed ID: 28892089
Y. Nihongaki, Y. Furuhata, T. Otabe, S. Hasegawa, K. Yoshimoto and M. Sato

A Modular Platform for Differentiation of Human PSCs into All Major Ectodermal Lineages. 2017, Cell Stem Cell, 21, 399-410.e7, PubMed ID: 28886367
J. Tchieu, B. Zimmer, F. Fattahi, S. Amin, N. Zeltner, S. Chen and L. Studer

Inhibition of DYRK1A disrupts neural lineage specificationin human pluripotent stem cells. 2017, Elife, 6, PubMed ID: 28884684
S. F. Bellmaine, D. A. Ovchinnikov, D. T. Manallack, C. E. Cuddy, A. G. Elefanty, E. G. Stanley, E. J. Wolvetang, S. J. Williams and M. Pera

Low-Density Neuronal Cultures from Human Induced Pluripotent Stem Cells. 2017, Mol Neuropsychiatry, 3, 28-36, PubMed ID: 28879199
P. Dimitrion, Y. Zhi, D. Clayton, G. L. Apodaca, M. R. Wilcox, J. W. Johnson, V. Nimgaonkar and L. D’Aiuto

Amyotrophic lateral sclerosis modifies progenitor neural proliferation in adult classic neurogenic brain niches. 2017, BMC Neurol, 17, 173, PubMed ID: 28874134
L. Galan, U. Gomez-Pinedo, A. Guerrero, J. M. Garcia-Verdugo and J. Matias-Guiu

Propofol-induced neurotoxicity in hESCs involved in activation of miR-206/PUMA signal pathway. 2017, Cancer Biomark, 20, 175-181, PubMed ID: 28869449
Y. Li, C. Jia, D. Zhang, G. Ni, X. Miao and R. Tu

A PITX3-EGFP Reporter Line Reveals Connectivity of Dopamine and Non-dopamine Neuronal Subtypes in Grafts Generated from Human Embryonic Stem Cells. 2017, Stem Cell Reports, 9, 868-882, PubMed ID: 28867345
J. C. Niclis, C. W. Gantner, C. P. J. Hunt, J. A. Kauhausen, J. C. Durnall, J. M. Haynes, C. W. Pouton, C. L. Parish and L. H. Thompson

iPSC-derived neuronal models of PANK2-associated neurodegeneration reveal mitochondrial dysfunction contributing to early disease. 2017, PLoS One, 12, e0184104, PubMed ID: 28863176
C. Arber, P. R. Angelova, S. Wiethoff, Y. Tsuchiya, F. Mazzacuva, E. Preza, K. P. Bhatia, K. Mills, I. Gout, A. Y. Abramov, J. Hardy, J. A. Duce, H. Houlden and S. Wray

Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model. 2017, Nature, 548, 592-596, PubMed ID: 28858313
T. Kikuchi, A. Morizane, D. Doi, H. Magotani, H. Onoe, T. Hayashi, H. Mizuma, S. Takara, R. Takahashi, H. Inoue, S. Morita, M. Yamamoto, K. Okita, M. Nakagawa, M. Parmar and J. Takahashi

Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation. 2017, Nat Protoc, 12, 1962-1979, PubMed ID: 28858290
S. Nolbrant, A. Heuer, M. Parmar and A. Kirkeby

Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors. 2017, Stem Cell Reports, 9, 820-837, PubMed ID: 28844659
A. Gonzalez-Cordero, K. Kruczek, A. Naeem, M. Fernando, M. Kloc, J. Ribeiro, D. Goh, Y. Duran, S. J. I. Blackford, L. Abelleira-Hervas, R. D. Sampson, I. O. Shum, M. J. Branch, P. J. Gardner, J. C. Sowden, J. W. B. Bainbridge, A. J. Smith, E. L. West, R. A. Pearson and R. R. Ali

Term amniotic fluid: an unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications. 2017, Stem Cell Res Ther, 8, 190, PubMed ID: 28841906
R. Moraghebi, A. Kirkeby, P. Chaves, R. E. Ronn, E. Sitnicka, M. Parmar, M. Larsson, A. Herbst and N. B. Woods

Transcriptional profiling of human neural precursors post alcohol exposure reveals impaired neurogenesis via dysregulation of ERK signaling and miR-145. 2017, J Neurochem, PubMed ID: 28833141
L. K. Louis, R. Gopurappilly, H. Surendran, S. Dutta and R. Pal

CRISPR/Cas9 and piggyBac-mediated footprint-free LRRK2-G2019S knock-in reveals neuronal complexity phenotypes and alpha-Synuclein modulation in dopaminergic neurons. 2017, Stem Cell Res, 24, 44-50, PubMed ID: 28826027
X. Qing, J. Walter, J. Jarazo, J. Arias-Fuenzalida, A. L. Hillje and J. C. Schwamborn

Prolonged human neural stem cell maturation supports recovery in injured rodent CNS. 2017, J Clin Invest, 127, 3287-3299, PubMed ID: 28825600
P. Lu, S. Ceto, Y. Wang, L. Graham, D. Wu, H. Kumamaru, E. Staufenberg and M. H. Tuszynski

An expandable embryonic stem cell-derived Purkinje neuron progenitor population that exhibits in vivo maturation in the adult mouse cerebellum. 2017, Sci Rep, 7, 8863, PubMed ID: 28821816
G. A. Higuera, G. Iaffaldano, M. Bedar, G. Shpak, R. Broersen, S. T. Munshi, C. Dupont, J. Gribnau, F. M. S. de Vrij, S. A. Kushner and C. I. De Zeeuw

Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells. 2017, Neuron, 95, 779-790.e6, PubMed ID: 28817799
S. A. Sloan, S. Darmanis, N. Huber, T. A. Khan, F. Birey, C. Caneda, R. Reimer, S. R. Quake, B. A. Barres and S. P. Pasca

Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental Loci. 2017, Cell Stem Cell, 21, 305-318.e8, PubMed ID: 28803920
M. P. Forrest, H. Zhang, W. Moy, H. McGowan, C. Leites, L. E. Dionisio, Z. Xu, J. Shi, A. R. Sanders, W. J. Greenleaf, C. A. Cowan, Z. P. Pang, P. V. Gejman, P. Penzes and J. Duan

Neural Crest Cell Implantation Restores Enteric Nervous System Function and Alters the Gastrointestinal Transcriptome in Human Tissue-Engineered Small Intestine. 2017, Stem Cell Reports, 9, 883-896, PubMed ID: 28803915
C. R. Schlieve, K. L. Fowler, M. Thornton, S. Huang, I. Hajjali, X. Hou, B. Grubbs, J. R. Spence and T. C. Grikscheit

Induced Pluripotent Stem Cell Neuronal Models for the Study of Autophagy Pathways in Human Neurodegenerative Disease. 2017, Cells, 6, PubMed ID: 28800101
N. Jimenez-Moreno, P. Stathakos, M. A. Caldwell and J. D. Lane

Modeling Glaucoma: Retinal Ganglion Cells Generated from Induced Pluripotent Stem Cells of Patients with SIX6 Risk Allele Show Developmental Abnormalities. 2017, Stem Cells, 35, 2239-2252, PubMed ID: 28792678
P. Teotia, M. J. Van Hook, C. S. Wichman, R. R. Allingham, M. A. Hauser and I. Ahmad

Induced neural stem cells as a means of treatment in Huntington’s disease. 2017, Expert Opin Biol Ther, 17, 1333-1343, PubMed ID: 28792249
K. A. Choi and S. Hong

Developing HiPSC Derived Serum Free Embryoid Bodies for the Interrogation of 3-D Stem Cell Cultures Using Physiologically Relevant Assays. 2017, J Vis Exp, PubMed ID: 28784957
A. W. Phillips, J. E. Nestor and M. W. Nestor

Directed Differentiation of Human Embryonic Stem Cells to Neural Crest Stem Cells, Functional Peripheral Neurons, and Corneal Keratocytes. 2017, Biotechnol J, 12, PubMed ID: 28762648
Q. Zhu, M. Li, C. Yan, Q. Lu, S. Wei, R. Gao, M. Yu, Y. Zou, G. Sriram, H. J. Tong, W. Hunziker, C. J. Seneviratne, Z. Gong, B. R. Olsen and T. Cao

Polysialylation at Early Stages of Oligodendrocyte Differentiation Promotes Myelin Repair. 2017, J Neurosci, 37, 8131-8141, PubMed ID: 28760868
S. Werneburg, H. L. S. Fuchs, I. Albers, H. Burkhardt, V. Gudi, T. Skripuletz, M. Stangel, R. Gerardy-Schahn and H. Hildebrandt

Fusion of Regionally Specified hPSC-Derived Organoids Models Human Brain Development and Interneuron Migration. 2017, Cell Stem Cell, 21, 383-398.e7, PubMed ID: 28757360
Y. Xiang, Y. Tanaka, B. Patterson, Y. J. Kang, G. Govindaiah, N. Roselaar, B. Cakir, K. Y. Kim, A. P. Lombroso, S. M. Hwang, M. Zhong, E. G. Stanley, A. G. Elefanty, J. R. Naegele, S. H. Lee, S. M. Weissman and I. H. Park

An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells. 2017, Stem Cell Reports, 9, 600-614, PubMed ID: 28757165
J. Tcw, M. Wang, A. A. Pimenova, K. R. Bowles, B. J. Hartley, E. Lacin, S. I. Machlovi, R. Abdelaal, C. M. Karch, H. Phatnani, P. A. Slesinger, B. Zhang, A. M. Goate and K. J. Brennand

Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes. 2017, Stem Cell Reports, 9, 615-628, PubMed ID: 28757163
S. M. Ho, B. J. Hartley, E. Flaherty, P. Rajarajan, R. Abdelaal, I. Obiorah, N. Barretto, H. Muhammad, H. P. Phatnani, S. Akbarian and K. J. Brennand

Rapid generation of OPC-like cells from human pluripotent stem cells for treating spinal cord injury. 2017, Exp Mol Med, 49, e361, PubMed ID: 28751784
D. S. Kim, S. J. Jung, J. S. Lee, B. Y. Lim, H. A. Kim, J. E. Yoo, D. W. Kim and J. W. Leem

Hair follicle-associated-pluripotent (HAP) stem cells. 2017, Cell Cycle, 16, 2169-2175, PubMed ID: 28749199
Y. Amoh and R. M. Hoffman

Monocyte depletion early after stroke promotes neurogenesis from endogenous neural stem cells in adult brain. 2017, Exp Neurol, 297, 129-137, PubMed ID: 28746827
C. Laterza, S. Wattananit, N. Uoshima, R. Ge, R. Pekny, D. Tornero, E. Monni, O. Lindvall and Z. Kokaia

Altered neurite morphology and cholinergic function of induced pluripotent stem cell-derived neurons from a patient with Kleefstra syndrome and autism. 2017, Transl Psychiatry, 7, e1179, PubMed ID: 28742076
J. Nagy, J. Kobolak, S. Berzsenyi, Z. Abraham, H. X. Avci, I. Bock, Z. Bekes, B. Hodoscsek, A. Chandrasekaran, A. Teglasi, P. Dezso, B. Kovanyi, E. T. Voros, L. Fodor, T. Szel, K. Nemeth, A. Balazs, A. Dinnyes, B. Lendvai, G. Levay and V. Roman

High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain. 2017, Cell Stem Cell, 21, 274-283.e5, PubMed ID: 28736217
T. Zhou, L. Tan, G. Y. Cederquist, Y. Fan, B. J. Hartley, S. Mukherjee, M. Tomishima, K. J. Brennand, Q. Zhang, R. E. Schwartz, T. Evans, L. Studer and S. Chen

Human iPSC Glial Mouse Chimeras Reveal Glial Contributions to Schizophrenia. 2017, Cell Stem Cell, 21, 195-208.e6, PubMed ID: 28736215
M. S. Windrem, M. Osipovitch, Z. Liu, J. Bates, D. Chandler-Militello, L. Zou, J. Munir, S. Schanz, K. McCoy, R. H. Miller, S. Wang, M. Nedergaard, R. L. Findling, P. J. Tesar and S. A. Goldman

Expression of Type I Cannabinoid Receptors at Different Stages of Neuronal Differentiation of Human Fibroblasts. 2017, Bull Exp Biol Med, 163, 272-275, PubMed ID: 28730390
M. Y. Bobrov, V. V. Bezuglov, L. G. Khaspekov, S. N. Illarioshkin, E. V. Novosadova and I. A. Grivennikov

Expansion of human midbrain floor plate progenitors from induced pluripotent stem cells increases dopaminergic neuron differentiation potential. 2017, Sci Rep, 7, 6036, PubMed ID: 28729666
S. Fedele, G. Collo, K. Behr, J. Bischofberger, S. Muller, T. Kunath, K. Christensen, A. L. Gundner, M. Graf, R. Jagasia and V. Taylor

Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function. 2017, Immunity, 47, 183-198.e6, PubMed ID: 28723550
K. Takata, T. Kozaki, C. Z. W. Lee, M. S. Thion, M. Otsuka, S. Lim, K. H. Utami, K. Fidan, D. S. Park, B. Malleret, S. Chakarov, P. See, D. Low, G. Low, M. Garcia-Miralles, R. Zeng, J. Zhang, C. C. Goh, A. Gul, S. Hubert, B. Lee, J. Chen, I. Low, N. B. Shadan, J. Lum, T. S. Wei, E. Mok, S. Kawanishi, Y. Kitamura, A. Larbi, M. Poidinger, L. Renia, L. G. Ng, Y. Wolf, S. Jung, T. Onder, E. Newell, T. Huber, E. Ashihara, S. Garel, M. A. Pouladi and F. Ginhoux

Lysophosphatidic acid signaling regulates the KLF9-PPARgamma axis in human induced pluripotent stem cell-derived neurons. 2017, Biochem Biophys Res Commun, 491, 223-227, PubMed ID: 28716732
T. Tsukahara, S. Yamagishi, Y. Matsuda and H. Haniu

miR146b5p promotes the neural conversion of pluripotent stem cells by targeting Smad4. 2017, Int J Mol Med, 40, 814-824, PubMed ID: 28713933
N. Zhang, Y. Lyu, X. Pan, L. Xu, A. Xuan, X. He, W. Huang and D. Long

Development of membrane ion channels during neural differentiation from human embryonic stem cells. 2017, Biochem Biophys Res Commun, 491, 166-172, PubMed ID: 28711494
S. Mirsadeghi, E. Shahbazi, K. Hemmesi, S. Nemati, H. Baharvand, J. Mirnajafi-Zadeh and S. Kiani

Elimination of undifferentiated human embryonic stem cells by cardiac glycosides. 2017, Sci Rep, 7, 5289, PubMed ID: 28706279
Y. T. Lin, C. K. Wang, S. C. Yang, S. C. Hsu, H. Lin, F. P. Chang, T. C. Kuo, C. N. Shen, P. M. Chiang, M. Hsiao, F. L. Lu and J. Lu

Small molecules for reprogramming and transdifferentiation. 2017, Cell Mol Life Sci, 74, 3553-3575, PubMed ID: 28698932
H. Qin, A. Zhao and X. Fu

Fibrin functionalization with synthetic adhesive ligands interacting with alpha6beta1 integrin receptor enhance neurite outgrowth of embryonic stem cell-derived neural stem/progenitors. 2017, Acta Biomater, 59, 243-256, PubMed ID: 28694236
J. Silva, A. R. Bento, D. Barros, T. L. Laundos, S. R. Sousa, P. Quelhas, M. M. Sousa, A. P. Pego and I. F. Amaral

Behavior of Xeno-Transplanted Undifferentiated Human Induced Pluripotent Stem Cells Is Impacted by Microenvironment Without Evidence of Tumors. 2017, Stem Cells Dev, 26, 1409-1423, PubMed ID: 28693365
V. Martinez-Cerdeno, B. L. Barrilleaux, A. McDonough, J. Ariza, B. T. K. Yuen, P. Somanath, C. T. Le, C. Steward, K. Horton-Sparks and P. S. Knoepfler

MAPT Genetic Variation and Neuronal Maturity Alter Isoform Expression Affecting Axonal Transport in iPSC-Derived Dopamine Neurons. 2017, Stem Cell Reports, 9, 587-599, PubMed ID: 28689993
J. E. Beevers, M. C. Lai, E. Collins, H. D. E. Booth, F. Zambon, L. Parkkinen, J. Vowles, S. A. Cowley, R. Wade-Martins and T. M. Caffrey

Spatiotemporal Proteomic Profiling of Human Cerebral Development. 2017, Mol Cell Proteomics, 16, 1548-1562, PubMed ID: 28687556
U. Djuric, D. C. Rodrigues, I. Batruch, J. Ellis, P. Shannon and P. Diamandis

Single-Cell Alternative Splicing Analysis with Expedition Reveals Splicing Dynamics during Neuron Differentiation. 2017, Mol Cell, 67, 148-161.e5, PubMed ID: 28673540
Y. Song, O. B. Botvinnik, M. T. Lovci, B. Kakaradov, P. Liu, J. L. Xu and G. W. Yeo

Nanofibrous scaffolds for the guidance of stem cell-derived neurons for auditory nerve regeneration. 2017, PLoS One, 12, e0180427, PubMed ID: 28672008
S. Hackelberg, S. J. Tuck, L. He, A. Rastogi, C. White, L. Liu, D. M. Prieskorn, R. J. Miller, C. Chan, B. R. Loomis, J. M. Corey, J. M. Miller and R. K. Duncan

Human induced pluripotent stem cell (hiPSC)-derived neurons respond to convulsant drugs when co-cultured with hiPSC-derived astrocytes. 2017, Toxicology, 389, 130-138, PubMed ID: 28666936
M. N. Ishii, K. Yamamoto, M. Shoji, A. Asami and Y. Kawamata

Protocol for the Differentiation of Human Induced Pluripotent Stem Cells into Mixed Cultures of Neurons and Glia for Neurotoxicity Testing. 2017, J Vis Exp, PubMed ID: 28654077
F. Pistollato, D. Canovas-Jorda, D. Zagoura and A. Price

Cyclic tetrapeptide HDAC inhibitors as potential therapeutics for spinal muscular atrophy: Screening with iPSC-derived neuronal cells. 2017, Bioorg Med Chem Lett, 27, 3289-3293, PubMed ID: 28648462
J. I. Lai, L. J. Leman, S. Ku, C. J. Vickers, C. A. Olsen, A. Montero, M. R. Ghadiri and J. M. Gottesfeld

Aqueous cigarette tar extracts disrupt corticogenesis from human embryonic stem cells in vitro. 2017, Environ Res, 158, 194-202, PubMed ID: 28647514
A. N. Begum, J. S. Aguilar and Y. Hong

Application of stem cell derived neuronal cells to evaluate neurotoxic chemotherapy. 2017, Stem Cell Res, 22, 79-88, PubMed ID: 28645005
C. Wing, M. Komatsu, S. M. Delaney, M. Krause, H. E. Wheeler and M. E. Dolan

Mitochondrial biogenesis and neural differentiation of human iPSC is modulated by idebenone in a developmental stage-dependent manner. 2017, Biogerontology, 18, 665-677, PubMed ID: 28643190
J. Augustyniak, J. Lenart, M. Zychowicz, P. P. Stepien and L. Buzanska

Neural Stem Cells and Human Induced Pluripotent Stem Cells to Model Rare CNS Diseases. 2017, CNS Neurol Disord Drug Targets, 16, 915-926, PubMed ID: 28641519
L. De Filippis, C. Zalfa and D. Ferrari

Role of the JNK Pathway in Varicella-Zoster Virus Lytic Infection and Reactivation. 2017, J Virol, 91, PubMed ID: 28637759
S. Kurapati, T. Sadaoka, L. Rajbhandari, B. Jagdish, P. Shukla, M. A. Ali, Y. J. Kim, G. Lee, J. I. Cohen and A. Venkatesan

Proneurogenic Effects of Trazodone in Murine and Human Neural Progenitor Cells. 2017, ACS Chem Neurosci, 8, 2027-2038, PubMed ID: 28636360
V. Bortolotto, F. Mancini, G. Mangano, R. Salem, E. Xia, E. Del Grosso, M. Bianchi, P. L. Canonico, L. Polenzani and M. Grilli

Testosterone Differentially Affects T Cells and Neurons in Murine and Human Models of Neuroinflammation and Neurodegeneration. 2017, Am J Pathol, 187, 1613-1622, PubMed ID: 28634006
M. G. Massa, C. David, S. Jorg, J. Berg, B. Gisevius, S. Hirschberg, R. A. Linker, R. Gold and A. Haghikia

Nrf2 pathway activation upon rotenone treatment in human iPSC-derived neural stem cells undergoing differentiation towards neurons and astrocytes. 2017, Neurochem Int, 108, 457-471, PubMed ID: 28627367
F. Pistollato, D. Canovas-Jorda, D. Zagoura and A. Bal-Price

Neural differentiation of human embryonic stem cells induced by the transgene-mediated overexpression of single transcription factors. 2017, Biochem Biophys Res Commun, 490, 296-301, PubMed ID: 28610919
M. Matsushita, Y. Nakatake, I. Arai, K. Ibata, K. Kohda, S. K. Goparaju, M. Murakami, M. Sakota, N. Chikazawa-Nohtomi, S. B. H. Ko, T. Kanai, M. Yuzaki and M. S. H. Ko

Amyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms. 2017, Mol Brain, 10, 22, PubMed ID: 28610619
M. Madill, K. McDonagh, J. Ma, A. Vajda, P. McLoughlin, T. O’Brien, O. Hardiman and S. Shen

Stem cell models of Alzheimer’s disease: progress and challenges. 2017, Alzheimers Res Ther, 9, 42, PubMed ID: 28610595
C. Arber, C. Lovejoy and S. Wray

An L-Glutamine Transporter Isoform for Neurogenesis Facilitated by L-Theanine. 2017, Neurochem Res, 42, 2686-2697, PubMed ID: 28597057
Y. Yoneda

Induced pluripotent stem cell-based modeling of neurodegenerative diseases: a focus on autophagy. 2017, J Mol Med (Berl), 95, 705-718, PubMed ID: 28593578
J. Jungverdorben, A. Till and O. Brustle

Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells. 2017, Stem Cell Reports, 8, 1757-1769, PubMed ID: 28591655
R. Santos, K. C. Vadodaria, B. N. Jaeger, A. Mei, S. Lefcochilos-Fogelquist, A. P. D. Mendes, G. Erikson, M. Shokhirev, L. Randolph-Moore, C. Fredlender, S. Dave, R. Oefner, C. Fitzpatrick, M. Pena, J. J. Barron, M. Ku, A. M. Denli, B. E. Kerman, P. Charnay, J. R. Kelsoe, M. C. Marchetto and F. H. Gage

A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response. 2017, Stem Cell Reports, 8, 1727-1742, PubMed ID: 28591653
W. Haenseler, S. N. Sansom, J. Buchrieser, S. E. Newey, C. S. Moore, F. J. Nicholls, S. Chintawar, C. Schnell, J. P. Antel, N. D. Allen, M. Z. Cader, R. Wade-Martins, W. S. James and S. A. Cowley

Brd4-Brd2 isoform switching coordinates pluripotent exit and Smad2-dependent lineage specification. 2017, EMBO Rep, 18, 1108-1122, PubMed ID: 28588073
R. Fernandez-Alonso, L. Davidson, J. Hukelmann, M. Zengerle, A. R. Prescott, A. Lamond, A. Ciulli, G. P. Sapkota and G. M. Findlay

Multi-level characterization of balanced inhibitory-excitatory cortical neuron network derived from human pluripotent stem cells. 2017, PLoS One, 12, e0178533, PubMed ID: 28586384
A. G. Nadadhur, J. Emperador Melero, M. Meijer, D. Schut, G. Jacobs, K. W. Li, J. J. J. Hjorth, R. M. Meredith, R. F. Toonen, R. E. Van Kesteren, A. B. Smit, M. Verhage and V. M. Heine

Understanding neurodevelopmental disorders using human pluripotent stem cell-derived neurons. 2017, Brain Pathol, 27, 508-517, PubMed ID: 28585386
C. Tamburini and M. Li

Modeling Parkinson’s disease with induced pluripotent stem cells harboring alpha-synuclein mutations. 2017, Brain Pathol, 27, 545-551, PubMed ID: 28585381
K. Singh Dolt, F. Hammachi and T. Kunath

Astrocytes in a dish: Using pluripotent stem cells to model neurodegenerative and neurodevelopmental disorders. 2017, Brain Pathol, 27, 530-544, PubMed ID: 28585380
L. A. Crompton, O. Cordero-Llana and M. A. Caldwell

Cryopreservation Maintains Functionality of Human iPSC Dopamine Neurons and Rescues Parkinsonian Phenotypes In Vivo. 2017, Stem Cell Reports, 9, 149-161, PubMed ID: 28579395
D. R. Wakeman, B. M. Hiller, D. J. Marmion, C. W. McMahon, G. T. Corbett, K. P. Mangan, J. Ma, L. E. Little, Z. Xie, T. Perez-Rosello, J. N. Guzman, D. J. Surmeier and J. H. Kordower

Concise Review: Criteria for Chamber-Specific Categorization of Human Cardiac Myocytes Derived from Pluripotent Stem Cells. 2017, Stem Cells, 35, 1881-1897, PubMed ID: 28577296
C. Kane and C. M. N. Terracciano

Neural differentiation of human induced pluripotent stem cells on polycaprolactone/gelatin bi-electrospun nanofibers. 2017, Mater Sci Eng C Mater Biol Appl, 78, 1195-1202, PubMed ID: 28575957
A. KarbalaeiMahdi, M. Shahrousvand, H. R. Javadi, M. Ghollasi, F. Norouz, M. Kamali and A. Salimi

Decreased neural precursor cell pool in NADPH oxidase 2-deficiency: From mouse brain to neural differentiation of patient derived iPSC. 2017, Redox Biol, 13, 82-93, PubMed ID: 28575744
Z. Nayernia, M. Colaianna, N. Robledinos-Anton, E. Gutzwiller, F. Sloan-Bena, E. Stathaki, Y. Hibaoui, A. Cuadrado, J. Hescheler, M. J. Stasia, T. Saric, V. Jaquet and K. H. Krause

Differentiation of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neurons in Mouse Hippocampal Slice Cultures. 2017, Front Cell Neurosci, 11, 143, PubMed ID: 28567004
T. Hiragi, M. Andoh, T. Araki, T. Shirakawa, T. Ono, R. Koyama and Y. Ikegaya

Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS. 2017, Cell Rep, 19, 1739-1749, PubMed ID: 28564594
C. E. Hall, Z. Yao, M. Choi, G. E. Tyzack, A. Serio, R. Luisier, J. Harley, E. Preza, C. Arber, S. J. Crisp, P. M. D. Watson, D. M. Kullmann, A. Y. Abramov, S. Wray, R. Burley, S. H. Y. Loh, L. M. Martins, M. M. Stevens, N. M. Luscombe, C. R. Sibley, A. Lakatos, J. Ule, S. Gandhi and R. Patani

Transplantation of reprogrammed neurons for improved recovery after stroke. 2017, Prog Brain Res, 231, 245-263, PubMed ID: 28554399
Z. Kokaia, D. Tornero and O. Lindvall

Reprogramming of somatic cells: iPS and iN cells. 2017, Prog Brain Res, 230, 53-68, PubMed ID: 28552235
V. Broccoli

Pluripotent stem cell-derived neurons for transplantation in Huntington’s disease. 2017, Prog Brain Res, 230, 263-281, PubMed ID: 28552232
M. Li and A. E. Rosser

Strategies for bringing stem cell-derived dopamine neurons to the clinic: The Kyoto trial. 2017, Prog Brain Res, 230, 213-226, PubMed ID: 28552230
J. Takahashi

Strategies for bringing stem cell-derived dopamine neurons to the clinic-The NYSTEM trial. 2017, Prog Brain Res, 230, 191-212, PubMed ID: 28552229
L. Studer

Strategies for bringing stem cell-derived dopamine neurons to the clinic: A European approach (STEM-PD). 2017, Prog Brain Res, 230, 165-190, PubMed ID: 28552228
A. Kirkeby, M. Parmar and R. A. Barker

Preparation, characterization, and banking of clinical-grade cells for neural transplantation: Scale up, fingerprinting, and genomic stability of stem cell lines. 2017, Prog Brain Res, 230, 133-150, PubMed ID: 28552226
A. Natalwala and T. Kunath

Modelling Autistic Neurons with Induced Pluripotent Stem Cells. 2017, Adv Anat Embryol Cell Biol, 224, 49-64, PubMed ID: 28551750
A. Kathuria, C. Sala, C. Verpelli and J. Price

New genes for accurate normalization of qRT-PCR results in study of iPS and iPS-derived cells. 2017, Gene, 626, 234-240, PubMed ID: 28546127
A. S. Artyukhov, E. B. Dashinimaev, V. O. Tsvetkov, A. P. Bolshakov, E. V. Konovalova, S. N. Kolbaev, E. A. Vorotelyak and A. V. Vasiliev

3D Bioprinting Human Induced Pluripotent Stem Cell Constructs for In Situ Cell Proliferation and Successive Multilineage Differentiation. 2017, Adv Healthc Mater, 6, PubMed ID: 28544655
Q. Gu, E. Tomaskovic-Crook, G. G. Wallace and J. M. Crook

Concise Review: Induced Pluripotent Stem Cell-Based Drug Discovery for Mitochondrial Disease. 2017, Stem Cells, 35, 1655-1662, PubMed ID: 28544378
G. Inak, C. Lorenz, P. Lisowski, A. Zink, B. Mlody and A. Prigione

Cell-type-specific genome editing with a microRNA-responsive CRISPR-Cas9 switch. 2017, Nucleic Acids Res, 45, e118, PubMed ID: 28525578
M. Hirosawa, Y. Fujita, C. J. C. Parr, K. Hayashi, S. Kashida, A. Hotta, K. Woltjen and H. Saito

Reprogramming cells from Gulf War veterans into neurons to study Gulf War illness. 2017, Neurology, 88, 1968-1975, PubMed ID: 28507260
L. Qiang, A. N. Rao, G. Mostoslavsky, M. F. James, N. Comfort, K. Sullivan and P. W. Baas

Schwann Cell Precursors from Human Pluripotent Stem Cells as a Potential Therapeutic Target for Myelin Repair. 2017, Stem Cell Reports, 8, 1714-1726, PubMed ID: 28506533
H. S. Kim, J. Lee, D. Y. Lee, Y. D. Kim, J. Y. Kim, H. J. Lim, S. Lim and Y. S. Cho

Accreditation of Biosafe Clinical-Grade Human Embryonic Stem Cells According to Chinese Regulations. 2017, Stem Cell Reports, 9, 366-380, PubMed ID: 28506532
Q. Gu, J. Wang, L. Wang, Z. X. Liu, W. W. Zhu, Y. Q. Tan, W. F. Han, J. Wu, C. J. Feng, J. H. Fang, L. Liu, L. Wang, W. Li, X. Y. Zhao, B. Y. Hu, J. Hao and Q. Zhou

Engineered hydrogels increase the post-transplantation survival of encapsulated hESC-derived midbrain dopaminergic neurons. 2017, Biomaterials, 136, 1-11, PubMed ID: 28505596
M. M. Adil, T. Vazin, B. Ananthanarayanan, G. M. C. Rodrigues, A. T. Rao, R. U. Kulkarni, E. W. Miller, S. Kumar and D. V. Schaffer

Generation of pure GABAergic neurons by transcription factor programming. 2017, Nat Methods, 14, 621-628, PubMed ID: 28504679
N. Yang, S. Chanda, S. Marro, Y. H. Ng, J. A. Janas, D. Haag, C. E. Ang, Y. Tang, Q. Flores, M. Mall, O. Wapinski, M. Li, H. Ahlenius, J. L. Rubenstein, H. Y. Chang, A. A. Buylla, T. C. Sudhof and M. Wernig

In vitro field potential monitoring on a multi-microelectrode array for the electrophysiological long-term screening of neural stem cell maturation. 2017, Analyst, 142, 1929-1937, PubMed ID: 28484750
D. Seidel, H. G. Jahnke, B. Englich, M. Girard and A. A. Robitzki

A CRISPR Approach to Neurodegenerative Diseases. 2017, Trends Mol Med, 23, 483-485, PubMed ID: 28478951
M. Kampmann

DNA Damage Response in Human Stem Cells and Neural Descendants. 2017, Methods Mol Biol, 1599, 375-390, PubMed ID: 28477133
J. M. Beckta, B. R. Adams and K. Valerie

Epigenetic and transcriptional modulation of WDR5, a chromatin remodeling protein, in Huntington’s disease human induced pluripotent stem cell (hiPSC) model. 2017, Mol Cell Neurosci, 82, 46-57, PubMed ID: 28476540
S. Baronchelli, A. La Spada, A. Ntai, A. Barbieri, P. Conforti, G. S. Jotti, S. Redaelli, A. Bentivegna, P. De Blasio and I. Biunno

Novel spliced variants of OCT4, OCT4C and OCT4C1, with distinct expression patterns and functions in pluripotent and tumor cell lines. 2017, Eur J Cell Biol, 96, 347-355, PubMed ID: 28476334
M. Malakootian, F. Mirzadeh Azad, P. Naeli, M. Pakzad, Y. Fouani, E. Taheri Bajgan, H. Baharvand and S. J. Mowla

Integration of CpG-free DNA induces de novo methylation of CpG islands in pluripotent stem cells. 2017, Science, 356, 503-508, PubMed ID: 28473583
Y. Takahashi, J. Wu, K. Suzuki, P. Martinez-Redondo, M. Li, H. K. Liao, M. Z. Wu, R. Hernandez-Benitez, T. Hishida, M. N. Shokhirev, C. R. Esteban, I. Sancho-Martinez and J. C. I. Belmonte

Genetic Rescue of Mitochondrial and Skeletal Muscle Impairment in an Induced Pluripotent Stem Cells Model of Coenzyme Q10 Deficiency. 2017, Stem Cells, 35, 1687-1703, PubMed ID: 28472853
D. Romero-Moya, C. Santos-Ocana, J. Castano, G. Garrabou, J. A. Rodriguez-Gomez, V. Ruiz-Bonilla, C. Bueno, P. Gonzalez-Rodriguez, A. Giorgetti, E. Perdiguero, C. Prieto, C. Moren-Nunez, D. J. Fernandez-Ayala, M. Victoria Cascajo, I. Velasco, J. M. Canals, R. Montero, D. Yubero, C. Jou, J. Lopez-Barneo, F. Cardellach, P. Munoz-Canoves, R. Artuch, P. Navas and P. Menendez

The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis. 2017, Neuron, 94, 550-568.e10, PubMed ID: 28472656
I. Aldiri, B. Xu, L. Wang, X. Chen, D. Hiler, L. Griffiths, M. Valentine, A. Shirinifard, S. Thiagarajan, A. Sablauer, M. E. Barabas, J. Zhang, D. Johnson, S. Frase, X. Zhou, J. Easton, J. Zhang, E. R. Mardis, R. K. Wilson, J. R. Downing and M. A. Dyer

Epigenomics of Retinal Development in Mice and Humans. 2017, Neuron, 94, 420-423, PubMed ID: 28472646
N. Lonfat and C. Cepko

Phenotyping Cellular Viability by Functional Analysis of Ion Channels: GlyR-Targeted Screening in NT2-N Cells. 2017, Methods Mol Biol, 1601, 205-214, PubMed ID: 28470528
K. Kuenzel, S. A. Mofrad and D. F. Gilbert

A Protocol for In Vitro High-Throughput Chemical Susceptibility Screening in Differentiating NT2 Stem Cells. 2017, Methods Mol Biol, 1601, 61-70, PubMed ID: 28470517
A. K. Menzner and D. F. Gilbert

Differentiation of Human Pluripotent Stem Cells into Mesodermal and Ectodermal Derivatives Is Independent of the Type of Isogenic Reprogrammed Somatic Cells. 2017, Acta Naturae, 9, 68-74, PubMed ID: 28461976
E. S. Philonenko, M. V. Shutova, E. A. Khomyakova, E. M. Vassina, O. S. Lebedeva, S. L. Kiselev and M. A. Lagarkova

Mitochondrial replacement in an iPSC model of Leber’s hereditary optic neuropathy. 2017, Aging (Albany NY), 9, 1341-1350, PubMed ID: 28455970
R. C. B. Wong, S. Y. Lim, S. S. C. Hung, S. Jackson, S. Khan, N. J. Van Bergen, E. De Smit, H. H. Liang, L. S. Kearns, L. Clarke, D. A. Mackey, A. W. Hewitt, I. A. Trounce and A. Pebay

Assembly of functionally integrated human forebrain spheroids. 2017, Nature, 545, 54-59, PubMed ID: 28445465
F. Birey, J. Andersen, C. D. Makinson, S. Islam, W. Wei, N. Huber, H. C. Fan, K. R. C. Metzler, G. Panagiotakos, N. Thom, N. A. O’Rourke, L. M. Steinmetz, J. A. Bernstein, J. Hallmayer, J. R. Huguenard and S. P. Pasca

Cell diversity and network dynamics in photosensitive human brain organoids. 2017, Nature, 545, 48-53, PubMed ID: 28445462
G. Quadrato, T. Nguyen, E. Z. Macosko, J. L. Sherwood, S. Min Yang, D. R. Berger, N. Maria, J. Scholvin, M. Goldman, J. P. Kinney, E. S. Boyden, J. W. Lichtman, Z. M. Williams, S. A. McCarroll and P. Arlotta

APOE epsilon4/epsilon4 diminishes neurotrophic function of human iPSC-derived astrocytes. 2017, Hum Mol Genet, 26, 2690-2700, PubMed ID: 28444230
J. Zhao, M. D. Davis, Y. A. Martens, M. Shinohara, N. R. Graff-Radford, S. G. Younkin, Z. K. Wszolek, T. Kanekiyo and G. Bu

A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model. 2017, PLoS One, 12, e0174074, PubMed ID: 28441409
X. Yuan, Z. Li, A. C. Baines, E. Gavriilaki, Z. Ye, Z. Wen, E. M. Braunstein, L. G. Biesecker, L. Cheng, X. Dong and R. A. Brodsky

Automated and manual patch clamp data of human induced pluripotent stem cell-derived dopaminergic neurons. 2017, Sci Data, 4, 170056, PubMed ID: 28440808
D. Franz, H. L. Olsen, O. Klink and J. Gimsa

Differentiation of V2a interneurons from human pluripotent stem cells. 2017, Proc Natl Acad Sci U S A, 114, 4969-4974, PubMed ID: 28438991
J. C. Butts, D. A. McCreedy, J. A. Martinez-Vargas, F. N. Mendoza-Camacho, T. A. Hookway, C. A. Gifford, P. Taneja, L. Noble-Haeusslein and T. C. McDevitt

Disrupted neuronal maturation in Angelman syndrome-derived induced pluripotent stem cells. 2017, Nat Commun, 8, 15038, PubMed ID: 28436452
J. J. Fink, T. M. Robinson, N. D. Germain, C. L. Sirois, K. A. Bolduc, A. J. Ward, F. Rigo, S. J. Chamberlain and E. S. Levine

Neuronal cells derived from human induced pluripotent stem cells as a functional tool of melanocortin system. 2017, Neuropeptides, 65, 10-20, PubMed ID: 28434791
N. Yamada-Goto, Y. Ochi, G. Katsuura, Y. Yamashita, K. Ebihara, M. Noguchi, J. Fujikura, D. Taura, M. Sone, K. Hosoda, P. E. Gottschall and K. Nakao

Docosahexaenoic acid promotes differentiation of photoreceptor cells in three-dimensional neural retinas. 2017, Neurosci Res, 123, 1-7, PubMed ID: 28433627
E. Arai, V. M. Parmar, B. Sahu, L. Perusek, T. Parmar and A. Maeda

Induced Pluripotent Stem Cell Modeling of Gaucher’s Disease: What Have We Learned? 2017, Int J Mol Sci, 18, PubMed ID: 28430167
D. M. Santos and G. Tiscornia

Dataset in support of the generation of Niemann-Pick disease Type C1 patient-specific iPS cell lines carrying the novel NPC1 mutation c.1180T>C or the prevalent c.3182T>C mutation – Analysis of pluripotency and neuronal differentiation. 2017, Data Brief, 12, 123-131, PubMed ID: 28413817
F. Peter, M. Trilck, M. Rabenstein, A. Rolfs and M. J. Frech

Derivation of mouse embryonic stem cell lines from tyrosine hydroxylase reporter mice crossed with a human SNCA transgenic mouse model of Parkinson’s disease. 2017, Stem Cell Res, 19, 17-20, PubMed ID: 28413000
M. Chumarina, C. Azevedo, J. Bigarreau, C. Vignon, K. S. Kim, J. Y. Li and L. Roybon

Novel Regulatory Mechanisms for the SoxC Transcriptional Network Required for Visual Pathway Development. 2017, J Neurosci, 37, 4967-4981, PubMed ID: 28411269
K. C. Chang, J. Hertz, X. Zhang, X. L. Jin, P. Shaw, B. A. Derosa, J. Y. Li, P. Venugopalan, D. A. Valenzuela, R. D. Patel, K. R. Russano, S. A. Alshamekh, C. Sun, K. Tenerelli, C. Li, D. Velmeshev, Y. Cheng, T. M. Boyce, A. Dreyfuss, M. S. Uddin, K. J. Muller, D. M. Dykxhoorn and J. L. Goldberg

High-Throughput and Cost-Effective Characterization of Induced Pluripotent Stem Cells. 2017, Stem Cell Reports, 8, 1101-1111, PubMed ID: 28410643
M. D’Antonio, G. Woodruff, J. L. Nathanson, A. D’Antonio-Chronowska, A. Arias, H. Matsui, R. Williams, C. Herrera, S. M. Reyna, G. W. Yeo, L. S. B. Goldstein, A. D. Panopoulos and K. A. Frazer

Inhibition of retrograde transport modulates misfolded protein accumulation and clearance in motoneuron diseases. 2017, Autophagy, 13, 1280-1303, PubMed ID: 28402699
R. Cristofani, V. Crippa, P. Rusmini, M. E. Cicardi, M. Meroni, N. V. Licata, G. Sala, E. Giorgetti, C. Grunseich, M. Galbiati, M. Piccolella, E. Messi, C. Ferrarese, S. Carra and A. Poletti

Isogenic blood-brain barrier models based on patient-derived stem cells display inter-individual differences in cell maturation and functionality. 2017, J Neurochem, 142, 74-88, PubMed ID: 28397247
R. Patel, S. Page and A. J. Al-Ahmad

Photoreceptor Outer Segment-like Structures in Long-Term 3D Retinas from Human Pluripotent Stem Cells. 2017, Sci Rep, 7, 766, PubMed ID: 28396597
K. J. Wahlin, J. A. Maruotti, S. R. Sripathi, J. Ball, J. M. Angueyra, C. Kim, R. Grebe, W. Li, B. W. Jones and D. J. Zack

Reporting on methods to generate and purify rodent and human oligodendrocytes from different sources. 2017, Stem Cell Res, 20, 58-66, PubMed ID: 28395742
M. Djelloul, C. Azevedo, Y. Pomeshchik, A. Hammarberg and L. Roybon

Application of induced pluripotent stem cells to understand neurobiological basis of bipolar disorder and schizophrenia. 2017, Psychiatry Clin Neurosci, 71, 579-599, PubMed ID: 28393474
Y. N. Liu, S. Y. Lu and J. Yao

Melanoma-Derived iPCCs Show Differential Tumorigenicity and Therapy Response. 2017, Stem Cell Reports, 8, 1379-1391, PubMed ID: 28392221
M. Bernhardt, D. Novak, Y. Assenov, E. Orouji, N. Knappe, K. Weina, M. Reith, L. Larribere, C. Gebhardt, C. Plass, V. Umansky and J. Utikal

Survival of human embryonic stem cells implanted in the guinea pig auditory epithelium. 2017, Sci Rep, 7, 46058, PubMed ID: 28387239
M. Y. Lee, S. Hackelberg, K. L. Green, K. G. Lunghamer, T. Kurioka, B. R. Loomis, D. L. Swiderski, R. K. Duncan and Y. Raphael

Genome-wide RNA-seq of iPSC-derived motor neurons indicates selective cytoskeletal perturbation in Brown-Vialetto disease that is partially rescued by riboflavin. 2017, Sci Rep, 7, 46271, PubMed ID: 28382968
F. Rizzo, A. Ramirez, C. Compagnucci, S. Salani, V. Melzi, A. Bordoni, F. Fortunato, A. Niceforo, N. Bresolin, G. P. Comi, E. Bertini, M. Nizzardo and S. Corti

Messenger RNAs localized to distal projections of human stem cell derived neurons. 2017, Sci Rep, 7, 611, PubMed ID: 28377585
R. L. Bigler, J. W. Kamande, R. Dumitru, M. Niedringhaus and A. M. Taylor

From the Cover: AstrocytesAre Protective Against Chlorpyrifos Developmental Neurotoxicity in Human Pluripotent Stem Cell-Derived Astrocyte-Neuron Cocultures. 2017, Toxicol Sci, 157, 410-420, PubMed ID: 28369648
X. Wu, X. Yang, A. Majumder, R. Swetenburg, F. T. Goodfellow, M. G. Bartlett and S. L. Stice

Personalized genome sequencing coupled with iPSC technology identifies GTDC1 as a gene involved in neurodevelopmental disorders. 2017, Hum Mol Genet, 26, 367-382, PubMed ID: 28365779
I. Aksoy, K. H. Utami, C. L. Winata, A. M. Hillmer, S. L. Rouam, S. Briault, S. Davila, L. W. Stanton and V. Cacheux

Effect of Nerve Growth Factor on Neural Differentiation of Mouse Embryonic Stem Cells. 2017, Bull Exp Biol Med, 162, 679-683, PubMed ID: 28364186
S. A. Antonov, E. S. Manuilova, O. V. Dolotov, A. G. Kobylyansky, D. R. Safina and I. A. Grivennikov

3D Culture for Self-Formation of the Cerebellum from Human Pluripotent Stem Cells Through Induction of the Isthmic Organizer. 2017, Methods Mol Biol, 1597, 31-41, PubMed ID: 28361308
K. Muguruma

FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons. 2017, Nat Commun, 8, 14741, PubMed ID: 28358055
L. Errichelli, S. Dini Modigliani, P. Laneve, A. Colantoni, I. Legnini, D. Capauto, A. Rosa, R. De Santis, R. Scarfo, G. Peruzzi, L. Lu, E. Caffarelli, N. A. Shneider, M. Morlando and I. Bozzoni

Mechanisms of iPS cell generation and beyond. 2017, Keio J Med, 66, 14, PubMed ID: 28356547
K. Kaji

Discrimination of Stem Cell Status after Subjecting Cynomolgus Monkey Pluripotent Stem Cells to Naive Conversion. 2017, Sci Rep, 7, 45285, PubMed ID: 28349944
A. Honda, Y. Kawano, H. Izu, N. Choijookhuu, K. Honsho, T. Nakamura, Y. Yabuta, T. Yamamoto, Y. Takashima, M. Hirose, T. Sankai, Y. Hishikawa, A. Ogura and M. Saitou

Simple Derivation of Spinal Motor Neurons from ESCs/iPSCs Using Sendai Virus Vectors. 2017, Mol Ther Methods Clin Dev, 4, 115-125, PubMed ID: 28344997
K. Goto, K. Imamura, K. Komatsu, K. Mitani, K. Aiba, N. Nakatsuji, M. Inoue, A. Kawata, H. Yamashita, R. Takahashi and H. Inoue

Abnormal Neural Progenitor Cells Differentiated from Induced Pluripotent Stem Cells Partially Mimicked Development of TSC2 Neurological Abnormalities. 2017, Stem Cell Reports, 8, 883-893, PubMed ID: 28344003
Y. Li, J. Cao, M. Chen, J. Li, Y. Sun, Y. Zhang, Y. Zhu, L. Wang and C. Zhang

Inducible and Deterministic Forward Programming of Human Pluripotent Stem Cells into Neurons, Skeletal Myocytes, and Oligodendrocytes. 2017, Stem Cell Reports, 8, 803-812, PubMed ID: 28344001
M. Pawlowski, D. Ortmann, A. Bertero, J. M. Tavares, R. A. Pedersen, L. Vallier and M. R. N. Kotter

Evidence brings hope for high-yield dopaminergic human-induced pluripotent stem cell transplant. 2017, Mov Disord, 32, 526, PubMed ID: 28339119
M. Sarfi and F. Rahmani

DNMT1 mutations found in HSANIE patients affect interaction with UHRF1 and neuronal differentiation. 2017, Hum Mol Genet, 26, 1522-1534, PubMed ID: 28334952
M. Smets, S. Link, P. Wolf, K. Schneider, V. Solis, J. Ryan, D. Meilinger, W. Qin and H. Leonhardt

Co-cultures with stem cell-derived human sensory neurons reveal regulators of peripheral myelination. 2017, Brain, 140, 898-913, PubMed ID: 28334857
A. J. Clark, M. S. Kaller, J. Galino, H. J. Willison, S. Rinaldi and D. L. H. Bennett

Cell survival and differentiation with nanocrystalline glass-like carbon using substantia nigra dopaminergic cells derived from transgenic mouse embryos. 2017, PLoS One, 12, e0173978, PubMed ID: 28334019
N. Rodriguez-Losada, P. Romero, G. Estivill-Torrus, R. Guzman de Villoria and J. A. Aguirre

Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons. 2017, Sci Rep, 7, 44840, PubMed ID: 28327614
W. Chuang, A. Sharma, P. Shukla, G. Li, M. Mall, K. Rajarajan, O. J. Abilez, R. Hamaguchi, J. C. Wu, M. Wernig and S. M. Wu

CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells. 2017, Mol Autism, 8, 11, PubMed ID: 28321286
P. Wang, R. Mokhtari, E. Pedrosa, M. Kirschenbaum, C. Bayrak, D. Zheng and H. M. Lachman

Developmental alterations in Huntington’s disease neural cells and pharmacological rescue in cells and mice. 2017, Nat Neurosci, 20, 648-660, PubMed ID: 28319609

Glycoconjugates reveal diversity of human neural stem cells (hNSCs) derived from human induced pluripotent stem cells (hiPSCs). 2017, Cell Tissue Res, 368, 531-549, PubMed ID: 28299522
M. Kandasamy, L. Roll, D. Langenstroth, O. Brustle and A. Faissner

Kisspeptin-10 treatment generated specific GnRH expression in cells differentiated from rhesus monkey derived Lyon NSCs. 2017, Neuroscience, 349, 318-329, PubMed ID: 28288899
T. Huma, X. Hu, Y. Ma, A. Willden, J. Rizak, M. Shahab and Z. Wang

Three-dimensional tissues using human pluripotent stem cell spheroids as biofabrication building blocks. 2017, Biofabrication, 9, 025007, PubMed ID: 28287080
H. Lin, Q. Li and Y. Lei

Phenotypic Screening Identifies Modulators of Amyloid Precursor Protein Processing in Human Stem Cell Models of Alzheimer’s Disease. 2017, Stem Cell Reports, 8, 870-882, PubMed ID: 28285880
P. W. Brownjohn, J. Smith, E. Portelius, L. Serneels, H. Kvartsberg, B. De Strooper, K. Blennow, H. Zetterberg and F. J. Livesey

Stroke alters behavior of human skin-derived neural progenitors after transplantation adjacent to neurogenic area in rat brain. 2017, Stem Cell Res Ther, 8, 59, PubMed ID: 28279192
C. de la Rosa-Prieto, C. Laterza, A. Gonzalez-Ramos, S. Wattananit, R. Ge, O. Lindvall, D. Tornero and Z. Kokaia

A Knockin Reporter Allows Purification and Characterization of mDA Neurons from Heterogeneous Populations. 2017, Cell Rep, 18, 2533-2546, PubMed ID: 28273465
N. Xia, F. Fang, P. Zhang, J. Cui, C. Tep-Cullison, T. Hamerley, H. J. Lee, T. Palmer, B. Bothner, J. H. Lee and R. R. Pera

Pig Induced Pluripotent Stem Cell-Derived Neural Rosettes Parallel Human Differentiation Into Sensory Neural Subtypes. 2017, Cell Reprogram, 19, 88-94, PubMed ID: 28266869
R. L. Webb, A. Gallegos-Cardenas, C. N. Miller, N. J. Solomotis, H. X. Liu, F. D. West and S. L. Stice

Accelerating practical applications of cutting edge human iPS cell technologies. 2017, Nihon Yakurigaku Zasshi, 149, 115-118, PubMed ID: 28260740
M. Lindner and G. Bauer

Astrocyte pathology in a human neural stem cell model of frontotemporal dementia caused by mutant TAU protein. 2017, Sci Rep, 7, 42991, PubMed ID: 28256506
A. L. Hallmann, M. J. Arauzo-Bravo, L. Mavrommatis, M. Ehrlich, A. Ropke, J. Brockhaus, M. Missler, J. Sterneckert, H. R. Scholer, T. Kuhlmann, H. Zaehres and G. Hargus

Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors. 2017, Proc Natl Acad Sci U S A, 114, E2243-e2252, PubMed ID: 28246330
M. Ehrlich, S. Mozafari, M. Glatza, L. Starost, S. Velychko, A. L. Hallmann, Q. L. Cui, A. Schambach, K. P. Kim, C. Bachelin, A. Marteyn, G. Hargus, R. M. Johnson, J. Antel, J. Sterneckert, H. Zaehres, H. R. Scholer, A. Baron-Van Evercooren and T. Kuhlmann

17beta-Oestradiol promotes differentiation of human embryonic stem cells into dopamine neurons via cross-talk between insulin-like growth factors-1 and oestrogen receptor beta. 2017, J Cell Mol Med, 21, 1605-1618, PubMed ID: 28244646
H. Li, C. Ding, Z. L. Ding, M. Ling, T. Wang, W. Wang and B. Huang

In Vitro Modeling of Blood-Brain Barrier with Human iPSC-Derived Endothelial Cells, Pericytes, Neurons, and Astrocytes via Notch Signaling. 2017, Stem Cell Reports, 8, 634-647, PubMed ID: 28238797
K. Yamamizu, M. Iwasaki, H. Takakubo, T. Sakamoto, T. Ikuno, M. Miyoshi, T. Kondo, Y. Nakao, M. Nakagawa, H. Inoue and J. K. Yamashita

EPHRIN-B1 Mosaicism Drives Cell Segregation in Craniofrontonasal Syndrome hiPSC-Derived Neuroepithelial Cells. 2017, Stem Cell Reports, 8, 529-537, PubMed ID: 28238796
T. K. Niethamer, A. R. Larson, A. K. O’Neill, M. Bershteyn, E. C. Hsiao, O. D. Klein, J. H. Pomerantz and J. O. Bush

Reversal of Phenotypic Abnormalities by CRISPR/Cas9-Mediated Gene Correction in Huntington Disease Patient-Derived Induced Pluripotent Stem Cells. 2017, Stem Cell Reports, 8, 619-633, PubMed ID: 28238795
X. Xu, Y. Tay, B. Sim, S. I. Yoon, Y. Huang, J. Ooi, K. H. Utami, A. Ziaei, B. Ng, C. Radulescu, D. Low, A. Y. J. Ng, M. Loh, B. Venkatesh, F. Ginhoux, G. J. Augustine and M. A. Pouladi

Differential Maturation of the Two Regulated Secretory Pathways in Human iPSC-Derived Neurons. 2017, Stem Cell Reports, 8, 659-672, PubMed ID: 28238793
J. Emperador Melero, A. G. Nadadhur, D. Schut, J. V. Weering, V. M. Heine, R. F. Toonen and M. Verhage

Hallmarks of Alzheimer’s Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain. 2017, Neuron, 93, 1066-1081.e8, PubMed ID: 28238547
I. Espuny-Camacho, A. M. Arranz, M. Fiers, A. Snellinx, K. Ando, S. Munck, J. Bonnefont, L. Lambot, N. Corthout, L. Omodho, E. Vanden Eynden, E. Radaelli, I. Tesseur, S. Wray, A. Ebneth, J. Hardy, K. Leroy, J. P. Brion, P. Vanderhaeghen and B. De Strooper

Distinctive genomic signature of neural and intestinal organoids from familial Parkinson’s disease patient-derived induced pluripotent stem cells. 2017, Neuropathol Appl Neurobiol, 43, 584-603, PubMed ID: 28235153
M. Y. Son, H. Sim, Y. S. Son, K. B. Jung, M. O. Lee, J. H. Oh, S. K. Chung, C. R. Jung and J. Kim

Bioamine-crosslinked gellan gum hydrogel for neural tissue engineering. 2017, Biomed Mater, 12, 025014, PubMed ID: 28233757
J. T. Koivisto, T. Joki, J. E. Parraga, R. Paakkonen, L. Yla-Outinen, L. Salonen, I. Jonkkari, M. Peltola, T. O. Ihalainen, S. Narkilahti and M. Kellomaki

Generation of kisspeptin-responsive GnRH neurons from human pluripotent stem cells. 2017, Mol Cell Endocrinol, 447, 12-22, PubMed ID: 28232089
A. Poliandri, D. Miller, S. Howard, M. Nobles, G. Ruiz-Babot, S. Harmer, A. Tinker, T. McKay, L. Guasti and L. Dunkel

Upscaling of hiPS Cell-Derived Neurons for High-Throughput Screening. 2017, SLAS Discov, 22, 274-286, PubMed ID: 28231034
S. Traub, H. Stahl, H. Rosenbrock, E. Simon and R. Heilker

Generation of Storable Retinal Organoids and Retinal Pigmented Epithelium from Adherent Human iPS Cells in Xeno-Free and Feeder-Free Conditions. 2017, Stem Cells, 35, 1176-1188, PubMed ID: 28220575
S. Reichman, A. Slembrouck, G. Gagliardi, A. Chaffiol, A. Terray, C. Nanteau, A. Potey, M. Belle, O. Rabesandratana, J. Duebel, G. Orieux, E. F. Nandrot, J. A. Sahel and O. Goureau

Direct Generation of Human Neuronal Cells from Adult Astrocytes by Small Molecules. 2017, Stem Cell Reports, 8, 538-547, PubMed ID: 28216149
L. Gao, W. Guan, M. Wang, H. Wang, J. Yu, Q. Liu, B. Qiu, Y. Yu, Y. Ping, X. Bian, L. Shen and G. Pei

Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B. 2017, Stem Cell Reports, 8, 648-658, PubMed ID: 28216144
Y. Zhang, B. Schmid, N. K. Nikolaisen, M. A. Rasmussen, B. I. Aldana, M. Agger, K. Calloe, T. C. Stummann, H. M. Larsen, T. T. Nielsen, J. Huang, F. Xu, X. Liu, L. Bolund, M. Meyer, L. K. Bak, H. S. Waagepetersen, Y. Luo, J. E. Nielsen, B. Holst, C. Clausen, P. Hyttel and K. K. Freude

Reprogramming cell fates by small molecules. 2017, Protein Cell, 8, 328-348, PubMed ID: 28213718
X. Ma, L. Kong and S. Zhu

Myotonic dystrophy type 1 patient-derived iPSCs for the investigation of CTG repeat instability. 2017, Sci Rep, 7, 42522, PubMed ID: 28211918
J. Ueki, M. Nakamori, M. Nakamura, M. Nishikawa, Y. Yoshida, A. Tanaka, A. Morizane, M. Kamon, T. Araki, M. P. Takahashi, A. Watanabe, N. Inagaki and H. Sakurai

Rapid differentiation of human pluripotent stem cells into functional neurons by mRNAs encoding transcription factors. 2017, Sci Rep, 7, 42367, PubMed ID: 28205555
S. K. Goparaju, K. Kohda, K. Ibata, A. Soma, Y. Nakatake, T. Akiyama, S. Wakabayashi, M. Matsushita, M. Sakota, H. Kimura, M. Yuzaki, S. B. Ko and M. S. Ko

Mild electrical stimulation with heat shock guides differentiation of embryonic stem cells into Pdx1-expressing cells within the definitive endoderm. 2017, BMC Biotechnol, 17, 14, PubMed ID: 28202025
T. Koga, N. Shiraki, S. Yano, M. A. Suico, S. Morino-Koga, T. Sato, T. Shuto, S. Kume and H. Kai

Applications of induced pluripotent stem cell technologies in spinal cord injury. 2017, J Neurochem, 141, 848-860, PubMed ID: 28199003
N. Nagoshi and H. Okano

Long-Distance Axonal Growth and Protracted Functional Maturation of Neurons Derived from Human Induced Pluripotent Stem Cells After Intracerebral Transplantation. 2017, Stem Cells Transl Med, 6, 1547-1556, PubMed ID: 28198124
J. C. Niclis, C. Turner, J. Durnall, S. McDougal, J. A. Kauhausen, B. Leaw, M. Dottori, C. L. Parish and L. H. Thompson

Proteasome impairment in neural cells derived from HMSN-P patient iPSCs. 2017, Mol Brain, 10, 7, PubMed ID: 28196470
N. Murakami, K. Imamura, Y. Izumi, N. Egawa, K. Tsukita, T. Enami, T. Yamamoto, T. Kawarai, R. Kaji and H. Inoue

Differentiation of oligodendrocyte progenitor cells from dissociated monolayer and feeder-free cultured pluripotent stem cells. 2017, PLoS One, 12, e0171947, PubMed ID: 28192470
T. Yamashita, Y. Miyamoto, Y. Bando, T. Ono, S. Kobayashi, A. Doi, T. Araki, Y. Kato, T. Shirakawa, Y. Suzuki, J. Yamauchi, S. Yoshida and N. Sato

Human Induced Pluripotent Cell-Derived Sensory Neurons for Fate Commitment of Bone Marrow-Derived Schwann Cells: Implications for Remyelination Therapy. 2017, Stem Cells Transl Med, 6, 369-381, PubMed ID: 28191772
S. Cai, L. Han, Q. Ao, Y. S. Chan and D. K. Shum

Preclinical Analysis of Fetal Human Mesencephalic Neural Progenitor Cell Lines: Characterization and Safety In Vitro and In Vivo. 2017, Stem Cells Transl Med, 6, 576-588, PubMed ID: 28191758
J. Moon, S. C. Schwarz, H. S. Lee, J. M. Kang, Y. E. Lee, B. Kim, M. Y. Sung, G. Hoglinger, F. Wegner, J. S. Kim, H. M. Chung, S. W. Chang, K. Y. Cha, K. S. Kim and J. Schwarz

Species-specific developmental timing is maintained by pluripotent stem cells ex utero. 2017, Dev Biol, 423, 101-110, PubMed ID: 28179190
C. Barry, M. T. Schmitz, P. Jiang, M. P. Schwartz, B. M. Duffin, S. Swanson, R. Bacher, J. M. Bolin, A. L. Elwell, B. E. McIntosh, R. Stewart and J. A. Thomson

Modeling the differential phenotypes of spinal muscular atrophy with high-yield generation of motor neurons from human induced pluripotent stem cells. 2017, Oncotarget, 8, 42030-42042, PubMed ID: 28159932
X. Lin, J. J. Li, W. J. Qian, Q. J. Zhang, Z. F. Wang, Y. Q. Lu, E. L. Dong, J. He, N. Wang, L. X. Ma and W. J. Chen

ATPase-deficient mitochondrial inner membrane protein ATAD3A disturbs mitochondrial dynamics in dominant hereditary spastic paraplegia. 2017, Hum Mol Genet, 26, 1432-1443, PubMed ID: 28158749
H. M. Cooper, Y. Yang, E. Ylikallio, R. Khairullin, R. Woldegebriel, K. L. Lin, L. Euro, E. Palin, A. Wolf, R. Trokovic, P. Isohanni, S. Kaakkola, M. Auranen, T. Lonnqvist, S. Wanrooij and H. Tyynismaa

Faithful SGCE imprinting in iPSC-derived cortical neurons: an endogenous cellular model of myoclonus-dystonia. 2017, Sci Rep, 7, 41156, PubMed ID: 28155872
K. Grutz, P. Seibler, A. Weissbach, K. Lohmann, F. A. Carlisle, D. J. Blake, A. Westenberger, C. Klein and A. Grunewald

In utero exposure to maternal smoking is associated with DNA methylation alterations and reduced neuronal content in the developing fetal brain. 2017, Epigenetics Chromatin, 10, 4, PubMed ID: 28149327
Z. Chatterton, B. J. Hartley, M. H. Seok, N. Mendelev, S. Chen, M. Milekic, G. Rosoklija, A. Stankov, I. Trencevsja-Ivanovska, K. Brennand, Y. Ge, A. J. Dwork and F. Haghighi

Generation of in vivo neural stem cells using partially reprogrammed cells defective in in vitro differentiation potential. 2017, Oncotarget, 8, 16456-16462, PubMed ID: 28147316
J. S. Kim, Y. J. Hong, H. W. Choi, H. Song, S. J. Byun and J. T. Do

Comparision of Gingival and Umbilical Cord Stem Cells Based on Its Modulus and Neuronal Differentiation. 2017, J Cell Biochem, 118, 2000-2008, PubMed ID: 28145578
R. Subbarayan, D. Murugan Girija, J. Mukherjee, S. R. R. Mamidanna and S. Ranga Rao

Reprogramming Postnatal Human Epidermal Keratinocytes Toward Functional Neural Crest Fates. 2017, Stem Cells, 35, 1402-1415, PubMed ID: 28142205
V. K. Bajpai, L. Kerosuo, G. Tseropoulos, K. A. Cummings, X. Wang, P. Lei, B. Liu, S. Liu, G. K. Popescu, M. E. Bronner and S. T. Andreadis

Dynamic behaviour of human neuroepithelial cells in the developing forebrain. 2017, Nat Commun, 8, 14167, PubMed ID: 28139695
L. Subramanian, M. Bershteyn, M. F. Paredes and A. R. Kriegstein

Differentiation of human telencephalic progenitor cells into MSNs by inducible expression of Gsx2 and Ebf1. 2017, Proc Natl Acad Sci U S A, 114, E1234-e1242, PubMed ID: 28137879
A. Faedo, A. Laporta, A. Segnali, M. Galimberti, D. Besusso, E. Cesana, S. Belloli, R. M. Moresco, M. Tropiano, E. Fuca, S. Wild, A. Bosio, A. E. Vercelli, G. Biella and E. Cattaneo

PC1/3 Deficiency Impacts Pro-opiomelanocortin Processing in Human Embryonic Stem Cell-Derived Hypothalamic Neurons. 2017, Stem Cell Reports, 8, 264-277, PubMed ID: 28132887
L. Wang, L. Sui, S. K. Panigrahi, K. Meece, Y. Xin, J. Kim, J. Gromada, C. A. Doege, S. L. Wardlaw, D. Egli and R. L. Leibel

Molecular dissection of germline chromothripsis in a developmental context using patient-derived iPS cells. 2017, Genome Med, 9, 9, PubMed ID:c 28126037
S. Middelkamp, S. van Heesch, A. K. Braat, J. de Ligt, M. van Iterson, M. Simonis, M. J. van Roosmalen, M. J. Kelder, E. Kruisselbrink, R. Hochstenbach, N. E. Verbeek, E. F. Ippel, Y. Adolfs, R. J. Pasterkamp, W. P. Kloosterman, E. W. Kuijk and E. Cuppen

Knock-in strategy at 3′-end of Crx gene by CRISPR/Cas9 system shows the gene expression profiles during human photoreceptor differentiation. 2017, Genes Cells, 22, 250-264, PubMed ID: 28124402
K. Homma, S. Usui and M. Kaneda

A systematic review: differentiation of stem cells into functional pericytes. 2017, Faseb j, 31, 1775-1786, PubMed ID: 28119398
J. Xu, T. Gong, B. C. Heng and C. F. Zhang

Rapid Neuronal Differentiation of Induced Pluripotent Stem Cells for Measuring Network Activity on Micro-electrode Arrays. 2017, J Vis Exp, PubMed ID: 28117798
M. Frega, S. H. van Gestel, K. Linda, J. van der Raadt, J. Keller, J. R. Van Rhijn, D. Schubert, C. A. Albers and N. Nadif Kasri

Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells. 2017, Nat Biotechnol, 35, 154-163, PubMed ID: 28112759
Y. Qi, X. J. Zhang, N. Renier, Z. Wu, T. Atkin, Z. Sun, M. Z. Ozair, J. Tchieu, B. Zimmer, F. Fattahi, Y. Ganat, R. Azevedo, N. Zeltner, A. H. Brivanlou, M. Karayiorgou, J. Gogos, M. Tomishima, M. Tessier-Lavigne, S. H. Shi and L. Studer

Zika virus disrupts molecular fingerprinting of human neurospheres. 2017, Sci Rep, 7, 40780, PubMed ID: 28112162
P. P. Garcez, J. M. Nascimento, J. M. de Vasconcelos, R. Madeiro da Costa, R. Delvecchio, P. Trindade, E. C. Loiola, L. M. Higa, J. S. Cassoli, G. Vitoria, P. C. Sequeira, J. Sochacki, R. S. Aguiar, H. T. Fuzii, A. M. de Filippis, J. L. da Silva Goncalves Vianez Junior, A. Tanuri, D. Martins-de-Souza and S. K. Rehen

Induced dopaminergic neurons: A new promise for Parkinson’s disease. 2017, Redox Biol, 11, 606-612, PubMed ID: 28110217
Z. Xu, X. Chu, H. Jiang, H. Schilling, S. Chen and J. Feng

Neuroregeneration of Induced Pluripotent Stem Cells in Polyacrylamide-Chitosan Inverted Colloidal Crystal Scaffolds with Poly(lactide-co-glycolide) Nanoparticles and Transactivator of Transcription von Hippel-Lindau Peptide. 2017, Tissue Eng Part A, 23, 263-274, PubMed ID: 28107800
Y. C. Kuo and C. W. Chen

Common developmental genome deprogramming in schizophrenia – Role of Integrative Nuclear FGFR1 Signaling (INFS). 2017, Schizophr Res, 185, 17-32, PubMed ID: 28094170
S. T. Narla, Y. W. Lee, C. A. Benson, P. Sarder, K. J. Brennand, E. K. Stachowiak and M. K. Stachowiak

Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages. 2017, Cell Stem Cell, 20, 29-40, PubMed ID: 28094018
N. Kee, N. Volakakis, A. Kirkeby, L. Dahl, H. Storvall, S. Nolbrant, L. Lahti, A. K. Bjorklund, L. Gillberg, E. Joodmardi, R. Sandberg, M. Parmar and T. Perlmann

Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson’s Disease. 2017, Cell Stem Cell, 20, 135-148, PubMed ID: 28094017
A. Kirkeby, S. Nolbrant, K. Tiklova, A. Heuer, N. Kee, T. Cardoso, D. R. Ottosson, M. J. Lelos, P. Rifes, S. B. Dunnett, S. Grealish, T. Perlmann and M. Parmar

A Single-Cell Roadmap of Lineage Bifurcation in Human ESC Models of Embryonic Brain Development. 2017, Cell Stem Cell, 20, 120-134, PubMed ID: 28094016
Z. Yao, J. K. Mich, S. Ku, V. Menon, A. R. Krostag, R. A. Martinez, L. Furchtgott, H. Mulholland, S. Bort, M. A. Fuqua, B. W. Gregor, R. D. Hodge, A. Jayabalu, R. C. May, S. Melton, A. M. Nelson, N. K. Ngo, N. V. Shapovalova, S. I. Shehata, M. W. Smith, L. J. Tait, C. L. Thompson, E. R. Thomsen, C. Ye, I. A. Glass, A. Kaykas, S. Yao, J. W. Phillips, J. S. Grimley, B. P. Levi, Y. Wang and S. Ramanathan

Stem cell therapies in preclinical models of stroke. Is the aged brain microenvironment refractory to cell therapy? 2017, Exp Gerontol, 94, 73-77, PubMed ID: 28093317
R. E. Sandu, A. T. Balseanu, C. Bogdan, M. Slevin, E. Petcu and A. Popa-Wagner

Efficient generation of hPSC-derived midbrain dopaminergic neurons in a fully defined, scalable, 3D biomaterial platform. 2017, Sci Rep, 7, 40573, PubMed ID: 28091566
M. M. Adil, G. M. Rodrigues, R. U. Kulkarni, A. T. Rao, N. E. Chernavsky, E. W. Miller and D. V. Schaffer

Fibrin hydrogels induce mixed dorsal/ventral spinal neuron identities during differentiation of human induced pluripotent stem cells. 2017, Acta Biomater, 51, 237-245, PubMed ID: 28088670
J. M. Edgar, M. Robinson and S. M. Willerth

Retinoblastoma protein controls growth, survival and neuronal migration in human cerebral organoids. 2017, Development, 144, 1025-1034, PubMed ID: 28087635
T. Matsui, V. Nieto-Estevez, S. Kyrychenko, J. W. Schneider and J. Hsieh

Understanding Parkinson’s Disease through the Use of Cell Reprogramming. 2017, Stem Cell Rev, 13, 151-169, PubMed ID: 28083784
R. Playne and B. Connor

Mitochondrial respiratory dysfunction disturbs neuronal and cardiac lineage commitment of human iPSCs. 2017, Cell Death Dis, 8, e2551, PubMed ID: 28079893
M. Yokota, H. Hatakeyama, Y. Ono, M. Kanazawa and Y. I. Goto

Katanin p80, NuMA and cytoplasmic dynein cooperate to control microtubule dynamics. 2017, Sci Rep, 7, 39902, PubMed ID: 28079116
M. Jin, O. Pomp, T. Shinoda, S. Toba, T. Torisawa, K. Furuta, K. Oiwa, T. Yasunaga, D. Kitagawa, S. Matsumura, T. Miyata, T. T. Tan, B. Reversade and S. Hirotsune

Highly Expandable Human iPS Cell-Derived Neural Progenitor Cells (NPC) and Neurons for Central Nervous System Disease Modeling and High-Throughput Screening. 2017, Curr Protoc Hum Genet, 92, 21.8.1-21.8.21, PubMed ID: 28075486
C. Cheng, D. M. Fass, K. Folz-Donahue, M. E. MacDonald and S. J. Haggarty

Culturing and Neuronal Differentiation of Human Dental Pulp Stem Cells. 2017, Curr Protoc Hum Genet, 92, 21.6.1-21.6.10, PubMed ID: 28075485
S. Goorha and L. T. Reiter

Human neural progenitors derived from integration-free iPSCs for SCI therapy. 2017, Stem Cell Res, 19, 55-64, PubMed ID: 28073086
Y. Liu, Y. Zheng, S. Li, H. Xue, K. Schmitt, G. W. Hergenroeder, J. Wu, Y. Zhang, D. H. Kim and Q. Cao

Characterising the developmental profile of human embryonic stem cell-derived medium spiny neuron progenitors and assessing mature neuron function using a CRISPR-generated human DARPP-32(WT/eGFP-AMP) reporter line. 2017, Neurochem Int, 106, 3-13, PubMed ID: 28065797
C. P. J. Hunt, C. W. Pouton and J. M. Haynes

Neurons Derived from Induced Pluripotent Stem Cells of Patients with Down Syndrome Reproduce Early Stages of Alzheimer’s Disease Type Pathology in vitro. 2017, J Alzheimers Dis, 56, 835-847, PubMed ID: 28059787
E. B. Dashinimaev, A. S. Artyuhov, A. P. Bolshakov, E. A. Vorotelyak and A. V. Vasiliev

Efficient induction of dopaminergic neuron differentiation from induced pluripotent stem cells reveals impaired mitophagy in PARK2 neurons. 2017, Biochem Biophys Res Commun, 483, 88-93, PubMed ID: 28057485
S. Suzuki, W. Akamatsu, F. Kisa, T. Sone, K. I. Ishikawa, N. Kuzumaki, H. Katayama, A. Miyawaki, N. Hattori and H. Okano

Functional Maturation of Human Stem Cell-Derived Neurons in Long-Term Cultures. 2017, PLoS One, 12, e0169506, PubMed ID: 28052116
R. S. Lam, F. M. Topfer, P. G. Wood, V. Busskamp and E. Bamberg

Increased susceptibility to Abeta toxicity in neuronal cultures derived from familial Alzheimer’s disease (PSEN1-A246E) induced pluripotent stem cells. 2017, Neurosci Lett, 639, 74-81, PubMed ID: 28034781
E. Armijo, C. Gonzalez, M. Shahnawaz, A. Flores, B. Davis and C. Soto

Three-dimensional culture of single embryonic stem-derived neural/stem progenitor cells in fibrin hydrogels: neuronal network formation and matrix remodelling. 2017, J Tissue Eng Regen Med, 11, 3494-3507, PubMed ID: 28032468
A. R. Bento, P. Quelhas, M. J. Oliveira, A. P. Pego and I. F. Amaral

Characterization of goat inner cell mass derived cells in double kinase inhibition condition. 2017, Biochem Biophys Res Commun, 483, 325-331, PubMed ID: 28025142
Q. Wei, Q. Xi, X. Liu, K. Meng, X. Zhao and B. Ma

A robust and reproducible human pluripotent stem cell derived model of neurite outgrowth in a three-dimensional culture system and its application to study neurite inhibition. 2017, Neurochem Int, 106, 74-84, PubMed ID: 28011165
K. E. Clarke, D. M. Tams, A. P. Henderson, M. F. Roger, A. Whiting and S. A. Przyborski

IGF1 neuronal response in the absence of MECP2 is dependent on TRalpha 3. 2017, Hum Mol Genet, 26, 270-281, PubMed ID: 28007906
J. S. de Souza, C. Carromeu, L. B. Torres, B. H. Araujo, F. R. Cugola, R. M. Maciel, A. R. Muotri and G. Giannocco

Stem Cell Transcriptome Responses and Corresponding Biomarkers That Indicate the Transition from Adaptive Responses to Cytotoxicity. 2017, Chem Res Toxicol, 30, 905-922, PubMed ID: 28001369
T. Waldmann, M. Grinberg, A. Konig, E. Rempel, S. Schildknecht, M. Henry, A. K. Holzer, N. Dreser, V. Shinde, A. Sachinidis, J. Rahnenfuhrer, J. G. Hengstler and M. Leist

A robust vitronectin-derived peptide for the scalable long-term expansion and neuronal differentiation of human pluripotent stem cell (hPSC)-derived neural progenitor cells (hNPCs). 2017, Acta Biomater, 48, 120-130, PubMed ID: 27989923
D. Varun, G. R. Srinivasan, Y. H. Tsai, H. J. Kim, J. Cutts, F. Petty, R. Merkley, N. Stephanopoulos, D. Dolezalova, M. Marsala and D. A. Brafman

The expanding horizon of MicroRNAs in cellular reprogramming. 2017, Prog Neurobiol, 148, 21-39, PubMed ID: 27979736
Y. K. Adlakha and P. Seth

Generation of Spinal Motor Neurons from Human Pluripotent Stem Cells. 2017, Methods Mol Biol, 1538, 53-66, PubMed ID: 27943183
D. P. Santos and E. Kiskinis

Direct Conversion of Human Fibroblasts into Neural Progenitors Using Transcription Factors Enriched in Human ESC-Derived Neural Progenitors. 2017, Stem Cell Reports, 8, 54-68, PubMed ID: 27940274
P. S. Hou, C. Y. Chuang, C. H. Yeh, W. Chiang, H. J. Liu, T. N. Lin and H. C. Kuo

A Comparative Study of Three Different Types of Stem Cells for Treatment of Rat Spinal Cord Injury. 2017, Cell Transplant, 26, 585-603, PubMed ID: 27938489
J. Ruzicka, L. Machova-Urdzikova, J. Gillick, T. Amemori, N. Romanyuk, K. Karova, K. Zaviskova, J. Dubisova, S. Kubinova, R. Murali, E. Sykova, M. Jhanwar-Uniyal and P. Jendelova

An isogenic blood-brain barrier model comprising brain endothelial cells, astrocytes, and neurons derived from human induced pluripotent stem cells. 2017, J Neurochem, 140, 874-888, PubMed ID: 27935037
S. G. Canfield, M. J. Stebbins, B. S. Morales, S. W. Asai, G. D. Vatine, C. N. Svendsen, S. P. Palecek and E. V. Shusta

Generation of neural cells using iPSCs from sleep bruxism patients with 5-HT2A polymorphism. 2017, J Prosthodont Res, 61, 242-250, PubMed ID: 27916472
Y. Hoashi, S. Okamoto, Y. Abe, T. Matsumoto, J. Tanaka, Y. Yoshida, K. Imaizumi, K. Mishima, W. Akamatsu, H. Okano and K. Baba

Examining FKBP5 mRNA expression in human iPSC-derived neural cells. 2017, Psychiatry Res, 247, 172-181, PubMed ID: 27915167
R. Lieberman, H. R. Kranzler, E. S. Levine and J. Covault

Epigenetics of cell fate reprogramming and its implications for neurological disorders modelling. 2017, Neurobiol Dis, 99, 84-120, PubMed ID: 27890672
M. Grzybek, A. Golonko, M. Walczak and P. Lisowski

A human brain microphysiological system derived from induced pluripotent stem cells to study neurological diseases and toxicity. 2017, Altex, 34, 362-376, PubMed ID: 27883356
D. Pamies, P. Barreras, K. Block, G. Makri, A. Kumar, D. Wiersma, L. Smirnova, C. Zang, J. Bressler, K. M. Christian, G. Harris, G. L. Ming, C. J. Berlinicke, K. Kyro, H. Song, C. A. Pardo, T. Hartung and H. T. Hogberg

Lin28a uses distinct mechanisms of binding to RNA and affects miRNA levels positively and negatively. 2017, Rna, 23, 317-332, PubMed ID: 27881476
J. S. Nowak, F. Hobor, A. Downie Ruiz Velasco, N. R. Choudhury, G. Heikel, A. Kerr, A. Ramos and G. Michlewski

Human hair-follicle associated pluripotent (hHAP) stem cells differentiate to cardiac-muscle cells. 2017, Cell Cycle, 16, 95-99, PubMed ID: 27880068
N. Tohgi, K. Obara, M. Yashiro, Y. Hamada, N. Arakawa, S. Mii, R. Aki, R. M. Hoffman and Y. Amoh

Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system. 2017, Nat Med, 23, 49-59, PubMed ID: 27869805
M. J. Workman, M. M. Mahe, S. Trisno, H. M. Poling, C. L. Watson, N. Sundaram, C. F. Chang, J. Schiesser, P. Aubert, E. G. Stanley, A. G. Elefanty, Y. Miyaoka, M. A. Mandegar, B. R. Conklin, M. Neunlist, S. A. Brugmann, M. A. Helmrath and J. M. Wells

Temporal expression of CD184(CXCR4) and CD171(L1CAM) identifies distinct early developmental stages of human retinal ganglion cells in embryonic stem cell derived retina. 2017, Exp Eye Res, 154, 177-189, PubMed ID: 27867005
J. G. Aparicio, H. Hopp, A. Choi, J. Mandayam Comar, V. C. Liao, N. Harutyunyan and T. C. Lee

Oleic acid promotes the expression of neural markers in differentiated human endometrial stem cells. 2017, J Chem Neuroanat, 79, 51-57, PubMed ID: 27865908
M. A. Kojour, S. Ebrahimi-Barough, H. M. Kouchesfehani, H. Jalali and M. H. Ebrahim

iPS-derived neural progenitor cells from PPMS patients reveal defect in myelin injury response. 2017, Exp Neurol, 288, 114-121, PubMed ID: 27865736
A. M. Nicaise, E. Banda, R. M. Guzzo, K. Russomanno, W. Castro-Borrero, C. M. Willis, K. M. Johnson, A. C. Lo and S. J. Crocker

Modeling Drug-Induced Neuropathy Using Human iPSCs for Predictive Toxicology. 2017, Clin Pharmacol Ther, 101, 754-762, PubMed ID: 27859025
R. Ohara, K. Imamura, F. Morii, N. Egawa, K. Tsukita, T. Enami, R. Shibukawa, T. Mizuno, M. Nakagawa and H. Inoue

Mesenchymal Stem Cells as a Source of Dopaminergic Neurons: A Potential Cell Based Therapy for Parkinson’s Disease. 2017, Curr Stem Cell Res Ther, 12, 326-347, PubMed ID: 27842480
K. Venkatesh and D. Sen

Generation of disease-specific autopsy-confirmed iPSCs lines from postmortem isolated Peripheral Blood Mononuclear Cells. 2017, Neurosci Lett, 637, 201-206, PubMed ID: 27826014
K. Belle, F. S. Shabazz, K. Nuytemans, D. A. Davis, A. Ali, J. L. Young, W. K. Scott, D. C. Mash, J. M. Vance and D. M. Dykxhoorn

Neurite extension and neuronal differentiation of human induced pluripotent stem cell derived neural stem cells on polyethylene glycol hydrogels containing a continuous Young’s Modulus gradient. 2017, J Biomed Mater Res A, 105, 824-833, PubMed ID: 27798956
M. C. Mosley, H. J. Lim, J. Chen, Y. H. Yang, S. Li, Y. Liu and L. A. Smith Callahan

The Transcriptional Changes of trim Genes Associated with Parkinson’s Disease on a Model of Human Induced Pluripotent Stem Cells. 2017, Mol Neurobiol, 54, 7204-7211, PubMed ID: 27796756
V. V. Nenasheva, E. V. Novosadova, I. V. Makarova, O. S. Lebedeva, M. A. Grefenshtein, E. L. Arsenyeva, S. A. Antonov, I. A. Grivennikov and V. Z. Tarantul

Electrophysiological properties of neurons derived from human stem cells and iNeurons in vitro. 2017, Neurochem Int, 106, 37-47, PubMed ID: 27742467
R. F. Halliwell

Neurotrophic Factor-alpha1: A Key Wnt-beta-Catenin Dependent Anti-Proliferation Factor and ERK-Sox9 Activated Inducer of Embryonic Neural Stem Cell Differentiation to Astrocytes in Neurodevelopment. 2017, Stem Cells, 35, 557-571, PubMed ID: 27709799
P. Selvaraj, L. Xiao, C. Lee, S. R. Murthy, N. X. Cawley, M. Lane, I. Merchenthaler, S. Ahn and Y. P. Loh

Generation of Functional Human Retinal Ganglion Cells with Target Specificity from Pluripotent Stem Cells by Chemically Defined Recapitulation of Developmental Mechanism. 2017, Stem Cells, 35, 572-585, PubMed ID: 27709736
P. Teotia, D. A. Chopra, S. M. Dravid, M. J. Van Hook, F. Qiu, J. Morrison, A. Rizzino and I. Ahmad

Development and characterization of a human embryonic stem cell-derived 3D neural tissue model for neurotoxicity testing. 2017, Toxicol In Vitro, 38, 124-135, PubMed ID: 27729293
J. Sandstrom, E. Eggermann, I. Charvet, A. Roux, N. Toni, C. Greggio, A. Broyer, F. Monnet-Tschudi and L. Stoppini

Stem Cells for Modeling and Therapy of Parkinson’s Disease. 2017, Hum Gene Ther, 28, 85-98, PubMed ID: 27762639
Q. Zhang, W. Chen, S. Tan and T. Lin

Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse Embryonic Stem Cells. 2017, Stem Cells, 35, 611-625, PubMed ID: 27739137
A. Stryjewska, R. Dries, T. Pieters, G. Verstappen, A. Conidi, K. Coddens, A. Francis, L. Umans, I. W. F. van, G. Berx, L. A. van Grunsven, F. G. Grosveld, S. Goossens, J. J. Haigh and D. Huylebroeck

Hypoxia Enhances Differentiation of Hair Follicle-Associated-Pluripotent (HAP) Stem Cells to Cardiac-Muscle Cells. 2017, J Cell Biochem, 118, 554-558, PubMed ID: 27627796
K. Shirai, Y. Hamada, N. Arakawa, A. Yamazaki, N. Tohgi, R. Aki, S. Mii, R. M. Hoffman and Y. Amoh

In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities. 2017, Arch Toxicol, 91, 1-33, PubMed ID: 27492622
B. Z. Schmidt, M. Lehmann, S. Gutbier, E. Nembo, S. Noel, L. Smirnova, A. Forsby, J. Hescheler, H. X. Avci, T. Hartung, M. Leist, J. Kobolak and A. Dinnyes

Establishment of Reporter Lines for Detecting Fragile X Mental Retardation (FMR1) Gene Reactivation in Human Neural Cells. 2017, Stem Cells, 35, 158-169, PubMed ID: 27422057
M. Li, H. Zhao, G. E. Ananiev, M. T. Musser, K. H. Ness, D. L. Maglaque, K. Saha, A. Bhattacharyya and X. Zhao

Metabotropic glutamate receptor 5 responses dictate differentiation of neural progenitors to NMDA-responsive cells in fragile X syndrome. 2017, Dev Neurobiol, 77, 438-453, PubMed ID: 27411166
V. S. Achuta, H. Grym, N. Putkonen, V. Louhivuori, V. Karkkainen, J. Koistinaho, L. Roybon and M. L. Castren

In vivo transplantation of fetal human gut-derived enteric neural crest cells. 2017, Neurogastroenterol Motil, 29, PubMed ID: 27380932
J. E. Cooper, D. Natarajan, C. J. McCann, S. Choudhury, H. Godwin, A. J. Burns and N. Thapar

Altered proliferation and networks in neural cells derived from idiopathic autistic individuals. 2017, Mol Psychiatry, 22, 820-835, PubMed ID: 27378147
M. C. Marchetto, H. Belinson, Y. Tian, B. C. Freitas, C. Fu, K. Vadodaria, P. Beltrao-Braga, C. A. Trujillo, A. P. D. Mendes, K. Padmanabhan, Y. Nunez, J. Ou, H. Ghosh, R. Wright, K. Brennand, K. Pierce, L. Eichenfield, T. Pramparo, L. Eyler, C. C. Barnes, E. Courchesne, D. H. Geschwind, F. H. Gage, A. Wynshaw-Boris and A. R. Muotri

Idiopathic Autism: Cellular and Molecular Phenotypes in Pluripotent Stem Cell-Derived Neurons. 2017, Mol Neurobiol, 54, 4507-4523, PubMed ID: 27356918
X. Liu, E. Campanac, H. H. Cheung, M. N. Ziats, L. Canterel-Thouennon, M. Raygada, V. Baxendale, A. L. Pang, L. Yang, S. Swedo, A. Thurm, T. L. Lee, K. P. Fung, W. Y. Chan, D. A. Hoffman and O. M. Rennert

In vitro models of cranial neural crest development toward toxicity tests: frog, mouse, and human. 2017, Oral Dis, 23, 559-565, PubMed ID: 27299949
M. Suga, Y. Hayashi and M. K. Furue

Bisphenol A Represses Dopaminergic Neuron Differentiation from Human Embryonic Stem Cells through Downregulating the Expression of Insulin-like Growth Factor 1. 2017, Mol Neurobiol, 54, 3798-3812, PubMed ID: 27271280
B. Huang, S. Ning, Q. Zhang, A. Chen, C. Jiang, Y. Cui, J. Hu, H. Li, G. Fan, L. Qin and J. Liu

miR-744 and miR-224 Downregulate Npas4 and Affect Lineage Differentiation Potential and Neurite Development During Neural Differentiation of Mouse Embryonic Stem Cells. 2017, Mol Neurobiol, 54, 3528-3541, PubMed ID: 27189618
F. C. Choy, T. S. Klaric, S. A. Koblar and M. D. Lewis

Functional effects of cannabinoids during dopaminergic specification of human neural precursors derived from induced pluripotent stem cells. 2017, Addict Biol, 22, 1329-1342, PubMed ID: 27027565
N. Stanslowsky, K. Jahn, A. Venneri, M. Naujock, A. Haase, U. Martin, H. Frieling and F. Wegner

Fingerprinting of neurotoxic compounds using a mouse embryonic stem cell dual luminescence reporter assay. 2017, Arch Toxicol, 91, 365-391, PubMed ID: 27015953
M. Colaianna, S. Ilmjarv, H. Peterson, I. Kern, S. Julien, M. Baquie, G. Pallocca, S. Bosgra, A. Sachinidis, J. G. Hengstler, M. Leist and K. H. Krause

Revisiting Mitochondrial Function and Metabolism in Pluripotent Stem Cells: Where Do We Stand in Neurological Diseases? 2017, Mol Neurobiol, 54, 1858-1873, PubMed ID: 26892627
C. Lopes and A. C. Rego

The therapeutic potential of cell identity reprogramming for the treatment of aging-related neurodegenerative disorders. 2017, Prog Neurobiol, 157, 212-229, PubMed ID: 26844759
D. K. Smith, M. He, C. L. Zhang and J. C. Zheng

Directed Differentiation of Dopamine-Secreting Cells from Nurr1/GPX1 Expressing Murine Embryonic Stem Cells Cultured on Matrigel-Coated PCL Scaffolds. 2017, Mol Neurobiol, 54, 1119-1128, PubMed ID: 26803497
P. Terraf, H. Babaloo and S. M. Kouhsari

In Vitro Differentiation of Human iPS Cells into Neural like Cells on a Biomimetic Polyurea. 2017, Mol Neurobiol, 54, 601-607, PubMed ID: 26746669
E. Hoveizi, S. Ebrahimi-Barough, S. Tavakol and K. Sanamiri

Epigenetic modifications in human fragile X pluripotent stem cells; Implications in fragile X syndrome modeling. 2017, Brain Res, 1656, 55-62, PubMed ID: 26475977
J. Gerhardt

New approaches for direct conversion of patient fibroblasts into neural cells. 2017, Brain Res, 1656, 2-13, PubMed ID: 26475975
S. Gopalakrishnan, P. Hor and J. K. Ichida

Modeling Huntingtons disease with patient-derived neurons. 2017, Brain Res, 1656, 76-87, PubMed ID: 26459990
V. B. Mattis and C. N. Svendsen

Transplantation of neurons derived from human iPS cells cultured on collagen matrix into guinea-pig cochleae. 2017, J Tissue Eng Regen Med, 11, 1766-1778, PubMed ID: 26205474
M. Ishikawa, H. Ohnishi, D. Skerleva, T. Sakamoto, N. Yamamoto, A. Hotta, J. Ito and T. Nakagawa

Regenerative therapy for hippocampal degenerative diseases: lessons from preclinical studies. 2017, J Tissue Eng Regen Med, 11, 321-333, PubMed ID: 26118731
C. Venugopal, S. Chandanala, H. C. Prasad, D. Nayeem, R. R. Bhonde and A. Dhanushkodi