Disease-specific iPS cells

(Last Update:2021.5.17)

* When you want to use some Disease-specific iPS cells, please e-mail to the following address.
* In relation to the information that are not described below, please e-mail to the following address.

Contact us : cellips.brcriken.jp

Blue letter cells are available. You obtain the information by clicking the blue letter.
*iPS cells created using the Sendai virus vector are now available

*Terms:
In relation to all iPS cell lines, approval of institutional review board and/or institutional ethical committee regarding the research using iPS cells is necessary.
In relation to all iPS cell lines, commercial use is prohibited.
In relation to the cell lines marked with ◎, (1) the recipient does not need to obtain an approval from the depositor, (2) there is no need of collaboration with the depositor, and (3) for-profit entities can also utilize.

Update : 2020.11.27

Disease groupNeuromuscular diseasesMetabolic diseasesSkin and connective tissue diseasesImmune diseasesCirculatory system diseasesHematologic diseasesKidney and urologic diseasesBone, cartilage, and articular diseasesEndocrine diseasesRespiratory tract diseasesEye diseasesOtorhinolaryngologic diseasesDigestive system diseasesDiseases due to chromosomal aberrations and gene mutationsOther diseasesHealthy relatives of patientsHealthy individuals (Clinical information is available only for users in Japan)Healthy individuals
Disease group Diseases Patients Cell line
Neuromuscular diseases 62 305 1201 NEW
Metabolic diseases 9 40 168 NEW
Skin and connective tissue diseases 8 23 126
Immune diseases 23 53 25
Circulatory system diseases 3 28 60 NEW
Hematologic diseases 8 26 128 NEW
Kidney and urologic diseases 7 17 67 NEW
Bone, cartilage, and articular diseases 11 41 126
Endocrine diseases 9 25 130
Respiratory tract diseases 9 19 106
Eye diseases 4 15 26
Otorhinolaryngologic diseases 1 1 3
Digestive system diseases 8 19 114 NEW
Diseases due to chromosomal aberrations and gene mutations 18 25 118
Other diseas 51 116 476
Total 231 753 3110
Diseases Patients Cell line
Healthy relatives of patients 9 13 64
Healthy individuals
(Clinical information is available only for users in Japan)
58 343
Healthy individuals 59 311
Total 9 130 718
Name of diseases Patient Cell line
Neuromuscular diseases
1 Spinal-Bulbar Muscular Atrophy (SBMA) 3 12
2 Amyotrophic lateral sclerosis (ALS) 67 256
3 Spinal muscular atrophy 4 16
4 Primary lateral sclerosis (PLS) 3 10
5 Progressive supranuclea palsy (PSP)  1 5
6 Parkinson’s disease (PD) 8 34
7 Corticobasal degeneration (CBD) 1 6
8 Huntington’s disease 2 7
9 Charcot-Marie-Tooth disease 11 23
10 Myasthenia Gravis (MG) 1 6
11 Congenital myasthenic syndrome 7 27
12 Multiple sclerosis (MS) / Neuromyelitis Optica Spectrum Disorders (NMOSD) 4 24
13 Chronic inflammatory demyelinating polyneuropathy (CIDP) / multifocal motor neuropathy (MMN) 2 12
14 Inclusion body myositis 2 4
15 Crow‐Fukase syndrome 2 10
16 Multiple system atrophy (MSA) 6 19
17 Spinocerebellar Degeneration 30 104
18 Moyamoya disease 4 21
19 Subacute sclerosing panencephalitis (SSPE) 2 12
20 Progressive multifocal leukoencephalopathy (PML) 1 5
21 Fahr disease 7 17 NEW
22 Ullrich congenital muscular dystrophy 2 4
23 Distal Myopathy 9 42
24 Bethlem myopathy 3 11
25 Danon disease 2 2
26 Schwartz-Jampel syndrome (SJS) 1 3
27 Congenital myopathy 4 15
28 Muscular dystrophy 31 107
29 Periodic paralysis 1 4
30 Syringomyelia 1 5
31 Isaacs syndrome 1 6
32 Hereditary dystonia 4 13
33 Neuroferritinopathy 1 1
34 Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy(CADASIL) 7 7
35 Perry syndrome 1 3
36 Frontotemporal lobar degeneration (FTLD) 3 14
37 Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD)  1 6
38 Congenital insensitivity to pain with anhidrosis 2 8
39 Alexander disease 5 25
40 Aicardi syndrome 1 6
41 Hemimegalencephaly 1 6
42 Focal cortical dysplasia (FCD) 2 12
43 Neuronal migration disorder 3 18
44 Dravet syndrom 3 18
45 Mesial temporal lobe epilepsy with hippocampal sclerosis 2 12
46 Epilepsy with myoclonic absence (EMA) 2 12
47 Epilepsy with myoclonic-astatic seizures 1 6
48 Lennox-Gastaut syndrome (LGS) 2 12
49 West syndrome 1 6
50 Ohtahara syndrome 1 6
51 Hemiconvulsion-hemiplegia-epilepsy syndrome 2 12
52 Ring chromosome 20 syndrome 2 12 NEW
53 Rasmussen encephalitis 2 12
54 PCDH19 epilepsy 2 12
55 Epilepsy with continuous spikes and waves during slow sleep 3 18
56 Landau―Kleffner syndrome 1 6
57 Rett syndrome 6 36 NEW
58 Sturge-Weber syndrome 1 6
59 Tuberous sclerosis complex (TSC) 1 6 NEW
60 Xeroderma pigmentosum 5 18
61 Angelman syndrome 11 26
62 Glycosylphosphatidylinositol(GPI) anchor deficiency  3 17
Total 305 1201
Name of diseases Patient Cell line
Skin and connective tissue diseases
1 Neurofibromatosis 3 18
2 Pemphigus 4 24
3 Pustular psoriasis 1 6
4 Stevens-Johnson syndrome (SJS) 1 6
5 Systemic sclerosis (SSc) 7 36
6 Congenital ichthyosis 1 6
7 Pemphigoid 3 18
8 Ehlers-Danlos syndrome 3 12
Total 23 126
Name of diseases Patient Cell line
Circulatory system diseases
1 Dilated cardiomyopathy (DCM) 17 34
2 Hypertrophic cardiomyopathy (HCM) 8 18
3 Tricuspid atresia 1 6
Total 28 60
Name of diseases Patient Cell line
Eye diseases
1 Retinitis pigmentosa 8 12
2 Macular degeneration 3 9
3 Leber Hereditary Optic Neuropathy 3 3
4 Gelatinous drop-like corneal dystrophy 1 2
Total 15 26
Name of diseases Patient Cell line
Otorhinolaryngologic diseases
1 Branchio-oto-renal syndrome 1 3
Total 1 3
Name of diseases Patient Cell line
Diseases due to chromosomal aberrations and gene mutations
1 Rubinstein-Taybi syndrom 1 6
2 CFC syndrome 1 6
3 Pachydermoperiostosis, possible case 1 6
4 Williams syndrome  2 12
5 ATR-X syndrome 2 5
6 Coffin-Siris syndrome 1 6
7 Kabuki syndrome  1 6
8 Werner syndrome 1 6
9 Cockayne’s syndrome 1 2
10 Prader-Willi Syndrome 3 8
11 Sotos Syndrome 2 12
12 Noonan syndrome 1 2
13 1p36 deletion syndrome 1 6
14 4p deletion syndrome 1 5
15 5p deletion syndrome 2 12
16 Smith-Magenis syndrome 1 6
17 22q11.2 deletion syndrome 2 10
18 Epstein syndrome 1 3
Total 25 118
Name of diseases Patient Cell line
Other diseases
1 Bardet-Biedl syndrome 1 2
2 Congenital Neutropenia, Kostmann syndrome 1 3
3 Juvenile nephronophthisis 2 6
4 Pendred Syndrome 3 3
5 Alzheimer’s disease 19 24
6 Dementia of Alzheimer’s type 1 7
7 Epilepsy 7 10
8 Age-related Macular Degeneration 2 12
9 Bietti crystalline retinopathy 4 24
10 Morphea with autoimmune hepatitis 1 6
11 Rheumatoid Arthritis 6 38
12 Reducing body myopathy 2 4
13 Bernard-Soulier syndorome 1 2
14 Langerhans cell histiocytosis 2 12
15 Refractory nephrotic syndrome 2 12
16 Muro disease (Kii ALS/PDC) 3 3
17 RAS-associated autoimmune leukoproliferative disorder (RALD) 2 7
18 Atopic dermatitis 1 1
19 Allergic rhinitis (Pollen allergy) 1 1
20 Colorectal cancer 3 22
21 Fulminant hepatitis 4 9
22 Familial atrial fibrillation / Sick sinus syndrome 4 4
23 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 1 2
24 Pancreatitis 3 18
25 Myelodysplastic syndromes  1 1
26 Lichen sclerosus et atrophicus 2 12
27 Protein S deficiency 1 6
28 Intrahepatic stones 1 2
29 Secondary antiphospholipid syndrome 1 6
30 Ossification of anterior longitudinal ligament 1 6
31 Primary aldosteronism 1 6
32 Guillain-Barré syndrome 1 6
33 Diffuse panbronchiolitis 1 6
34 Myelofibrosis 1 3
35 Aicardi Goutiares syndrome  1 6
36 Multiple endocrine neoplasia  1 6
37 Von Hippel-Lindau disease 3 18
38 Hereditary pheochromocytoma/ paraganglioma syndrome 1 6
39 Congenital metabolic disorder  1 6
40 NGLY1 deficiency  3 18
41 Autism spectrum disorde  3 18
42 Congenital diabetes insipidus  1 6
43 Developmental delay, epilepsy, neonatal diabetes  1 6
44 Hypochondroplasia 2 3
45 Familial adenomatous polyposis  2 6
46 Gastric cancer  2 32
47 Retinoblastoma  3 46
48 X-linked thrombocytopenia (XLT) 1 3
49 Spastic paraplegia 1 3
50 Downsyndrome 2 6
51 Congenital muscle type laminopathy 1 3
Total 116 478
Patients Cell line
Healthy individuals
(Clinical information is available only for users in Japan)
1 30s Male 10 60
2 30s Female 3 18
3 40s Male 10 60
4 40s Female 3 18
5 50s Male 10 59
6 50s Female 3 17
7 60s Male 10 60
8 70s Male 8 47
9 80s Male 1 6
Total 58 343
Patients Cell line
Healthy individuals
1 10s Female 1 1
2 20s Male 1 1
3 30s Male 7 30
4 40s Male 9 51
5 40s Female 7 38
6 50s Male 3 18
6 50s Female 11 66
7 60s Male 8 45
9 60s Female 6 27
10 70s Male 3 18
11 70s Female 2 10
12 80s Female 1 6
Total 59 311


Comments are closed.