Chromosomal Location | 11p15.5 |
Genebank Locus and Locus Definition | HUMANTH01, Human tyrosine hydroxylase gene |
Repeat Sequence 5′ – 3′ | AATG(*) |
Fluorecent Label | TMR:5'-terminal carboxy-tetramethylrhodamine label |
Size Range of allelic ladder components(**, ****) (bases) | 179-203 |
Repeat Numbers of allelic ladder components | 5-11 |
Repeat Numbers of alleles not present in allelic ladder | 8.3***, 9.3*** |
Commercial Product | PowerPlexTM 1.2 System of the Promega Co. |
(*) Repeat sequences represent all four possible permutations (e.g. AGAT is used for AGAT, GATA, ATAG or TAGA). The first alphabetic representation of the repeat (e.g., AGAT) is employed according to the precedent of Edwards et at.
(**) Length described in this table may differ from previous versions of allelic ladders for the same loci either because primers have been modified and/or new alleles have been identified (e.g., allelic ladders included with the GenePrintTM CTTv fluorescent STR Multiplex (lot#55275) do not contain CSF1PO allele 6 or vWA alleles 11 and 21; and allelic ladders included with the GenePrintTM CTTv Fluorescent STR Multiplex (lot#41430) do not contain CSF1PO allele6, TPOX alleles 6.7 and 13, and vWA alleles 11 and 21.
(***) The TH01 allele 9.3 is quite common, while allele 8.3 is extremely rare. Other extremely rare variants have been reported at the TH01 locus.
(****) Length of each allele in the allelic ladders have been confirmed by sequence analysis.