{"id":7882,"date":"2014-11-19T10:37:19","date_gmt":"2014-11-19T01:37:19","guid":{"rendered":"http:\/\/cell0.cell.rbrc.jp\/?page_id=7882"},"modified":"2014-11-19T14:33:02","modified_gmt":"2014-11-19T05:33:02","slug":"mn20141119","status":"publish","type":"page","link":"http:\/\/cell.brc.riken.jp\/ja\/mail_news\/mn20141119","title":{"rendered":"MAILNEWS 20141119\u53f7\uff08\u96fb\u5b50\u30e1\u30fc\u30eb\u7248\uff09"},"content":{"rendered":"
\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\r\nRIKEN BioResource Center Cell Bank\r\n\u3000\u3000\u3000MAILNEWS  20141119\u53f7\uff08\u96fb\u5b50\u30e1\u30fc\u30eb\u7248\uff09\r\n       http:\/\/cell.brc.riken.jp\/<\/a>\r\n\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\u2605\r\n\r\n==========================================================\r\n\u25a0 \u65b0\u898f\u63d0\u4f9b\u7d30\u80de\u6750\u6599\u306e\u304a\u77e5\u3089\u305b\r\n\u25a0 \u7b2c37\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u3000\u51fa\u5c55\u306e\u304a\u77e5\u3089\u305b\r\n\u25a0 \u7b2c43\u56de\u65e5\u672c\u514d\u75ab\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u3000\u51fa\u5c55\u306e\u304a\u77e5\u3089\u305b\r\n\u25a0 2014\u5e74\u30012015\u5e74\u3000\u5e74\u672b\u5e74\u59cb\u306e\u767a\u9001\u65e5\u306e\u304a\u77e5\u3089\u305b\r\n\u25a0 \u3072\u3068\u308a\u3054\u3068\r\n==========================================================\r\n\u6b21\u53f7\u304b\u3089\u306e MAILNEWS \u306e\u914d\u4fe1\u4e2d\u6b62\u3092\u3054\u5e0c\u671b\u306e\u65b9 \u2192 cellbank@brc.riken.jp<\/a>\u3078\r\n         \u6240\u5c5e\u3001\u6c0f\u540d\u3001\u30e1\u30fc\u30eb\u30a2\u30c9\u30ec\u30b9\u3092\u304a\u77e5\u3089\u305b\u4e0b\u3055\u3044\u3002\r\n\r\n==========================================================\r\n\u25a0\u3000\u65b0\u898f\u63d0\u4f9b\u7d30\u80de\u6750\u6599\u306e\u304a\u77e5\u3089\u305b\r\n==========================================================\r\nhttp:\/\/cell.brc.riken.jp\/shinkiteikyou<\/a>\r\n\r\n\u25ce  \u30d2\u30c8ES\u7d30\u80de\uff08HES\uff09\u3000\u65b0\u898f\u63d0\u4f9b\u7d30\u80de\u6750\u6599\u30003\u682a\r\nHES0006\u3000SEES1 \u30d2\u30c8\u80da\u6027\u5e79\uff08ES\uff09\u7d30\u80de\u682a\r\nHES0007\u3000SEES2 \u30d2\u30c8\u80da\u6027\u5e79\uff08ES\uff09\u7d30\u80de\u682a\r\nHES0008\u3000SEES3 \u30d2\u30c8\u80da\u6027\u5e79\uff08ES\uff09\u7d30\u80de\u682a\r\n\r\n\u25ce  \u30d2\u30c8iPS\u7d30\u80de\uff08HPS\uff09\u3000\u65b0\u898f\u63d0\u4f9b\u7d30\u80de\u6750\u6599\u30006\u682a\r\nHPS0142\u3000\u75be\u60a3\u7279\u7570\u7684iPS\u7d30\u80de\u682a\u3002\u5bb6\u65cf\u6027\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7\u60a3\u8005\u7531\u6765\u3002HPS0140\r\n\u3000\u3000\u3000\u3000\u3000\u3068\u540c\u4e00\u4eba\u7531\u6765\u3002\u30bb\u30f3\u30c0\u30a4\u30a6\u30a4\u30eb\u30b9\u30d9\u30af\u30bf\u30fc\u3092\u7528\u3044\u30664\u56e0\u5b50\uff08Oct3\/4,\r\n\u3000\u3000\u3000\u3000\u3000Sox2, Klf4, c-Myc\uff09\u3092\u5c0e\u5165\u3057\u3066\u6a39\u7acb\u3002\r\nHPS0147\u3000\u75be\u60a3\u7279\u7570\u7684iPS\u7d30\u80de\u682a\u3002\u5b64\u767a\u6027\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7 (bulbar, with UMN)\r\n\u3000\u3000\u3000\u3000\u3000\u60a3\u8005\u7531\u6765\u3002HPS0146\u3068\u540c\u4e00\u4eba\u7531\u6765\u3002\u30bb\u30f3\u30c0\u30a4\u30a6\u30a4\u30eb\u30b9\u30d9\u30af\u30bf\u30fc\u3092\u7528\u3044\r\n\u3000\u3000\u3000\u3000\u3000\u30664\u56e0\u5b50\uff08Oct3\/4, Sox2,Klf4, c-Myc\uff09\u3092\u5c0e\u5165\u3057\u3066\u6a39\u7acb\u3002\r\nHPS0191\u3000\u75be\u60a3\u7279\u7570\u7684iPS\u7d30\u80de\u682a\u3002\u30d9\u30eb\u30ca\u30fc\u30eb\u30fb\u30b9\u30fc\u30ea\u30a8\u75c7\u5019\u7fa4\u60a3\u8005\u7531\u6765\u3002\u30ec\u30c8\u30ed\r\n\u3000\u3000\u3000\u3000\u3000\u30a6\u30a4\u30eb\u30b9\u30d9\u30af\u30bf\u30fc\u306b\u3088\u308a3\u56e0\u5b50\uff08Oct3\/4, Sox2, Klf4\uff09\u3092\u5c0e\u5165\u3057\u3066\u6a39\r\n\u3000\u3000\u3000\u3000\u3000\u7acb\u3002\r\nHPS0200\u3000\u75be\u60a3\u7279\u7570\u7684iPS\u7d30\u80de\u682a\u3002\u80a2\u4f53\u578b\u7b4b\u30b8\u30b9\u30c8\u30ed\u30d5\u30a3\u30fc\u60a3\u8005\u7531\u6765\u3002\u30bb\u30f3\u30c0\u30a4\u30a6\r\n\u3000\u3000\u3000\u3000\u3000\u30a4\u30eb\u30b9\u30d9\u30af\u30bf\u30fc\u3092\u7528\u3044\u30664\u56e0\u5b50\uff08Oct3\/4, Sox2, Klf4, c-Myc\uff09\u3092\u5c0e\u5165\r\n\u3000\u3000\u3000\u3000\u3000\u3057\u3066\u6a39\u7acb\u3002\r\nHPS0317\u3000\u75be\u60a3\u7279\u7570\u7684iPS\u7d30\u80de\u682a\u3002\u30c7\u30e5\u30b7\u30e3\u30f3\u30cc\u578b\u7b4b\u30b8\u30b9\u30c8\u30ed\u30d5\u30a3\u30fc\u60a3\u8005\u7531\u6765\u3002\r\n\u3000\u3000\u3000\u3000\u3000HPS0322\u3068\u540c\u4e00\u4eba\u7531\u6765\u3002\u30ec\u30c8\u30ed\u30a6\u30a4\u30eb\u30b9\u30d9\u30af\u30bf\u30fc\u306b\u3088\u308a5\u56e0\u5b50\r\n\u3000\u3000\u3000\u3000\u3000\uff08Oct3\/4, Sox2, Klf4, Nanog, LIN28\uff09\u3092\u5c0e\u5165\u3057\u3066\u6a39\u7acb\u3002\r\nHPS0322\u3000\u75be\u60a3\u7279\u7570\u7684iPS\u7d30\u80de\u682a\u3002\u30c7\u30e5\u30b7\u30e3\u30f3\u30cc\u578b\u7b4b\u30b8\u30b9\u30c8\u30ed\u30d5\u30a3\u30fc\u60a3\u8005\u7531\u6765\u3002\r\n\u3000\u3000\u3000\u3000\u3000HPS0317\u3068\u540c\u4e00\u4eba\u7531\u6765\u3002\u30bb\u30f3\u30c0\u30a4\u30a6\u30a4\u30eb\u30b9\u30d9\u30af\u30bf\u30fc\u3092\u7528\u3044\u30664\u56e0\u5b50\r\n\u3000\u3000\u3000\u3000\u3000\uff08Oct3\/4, Sox2, Klf4, c-Myc\uff09\u3092\u5c0e\u5165\u3057\u3066\u6a39\u7acb\u3002\r\n\r\n\u25ce  \u30de\u30a6\u30b9ES\u7d30\u80de (AES)\u3000\u65b0\u898f\u63d0\u4f9b\u7d30\u80de\u6750\u6599\u30001\u682a\r\nAES0196\u3000MVh-Venns GS\u3000\u3053\u306eGS\u7d30\u80de\u682a\u306f\u3001\u751f\u6b96\u7cfb\u5217\u7279\u7570\u7684\u30ec\u30dd\u30fc\u30bf\u30fc\u767a\u73fe\u3092\u793a\r\n\u3000\u3000\u3000\u3000\u3000\u3059\u30c8\u30e9\u30f3\u30b9\u30b8\u30a7\u30cb\u30c3\u30af\u30de\u30a6\u30b9(Tg(Mvh-Venus) 1Rbrc)\u304b\u3089\u6a39\u7acb\u3055\u308c\u305f\r\n\u3000\u3000\u3000\u3000\u3000(\u30d8\u30df\u63a5\u5408\u4f53)\u3002\u751f\u6b96\u7d30\u80de\u7cfb\u5217\u30de\u30fc\u30ab\u30fc\u907a\u4f1d\u5b50\u3067\u3042\u308bMouse Vasa \r\n\u3000\u3000\u3000\u3000\u3000homolog(Mvh \u6216\u3044\u306f Ddx4)\u3092\u542b\u3080BAC\u30af\u30ed\u30fc\u30f3\u4e2d\u306eMvh\u907a\u4f1d\u5b50\u306e\u7b2c\uff12\u30a8\r\n\u3000\u3000\u3000\u3000\u3000\u30af\u30bd\u30f3\u306b\u86cd\u5149\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30b3\u30fc\u30c9\u3059\u308bVenus\u907a\u4f1d\u5b50\u304c\u633f\u5165\u3055\u308c\u3066\u3044\u308b\u3002\r\n\r\n\u25ce  \u52d5\u7269\u7531\u6765\u7d30\u80de\u3001\u30d2\u30c8\u7531\u6765\u7d30\u80de\u3000\u65b0\u898f\u63d0\u4f9b\u7d30\u80de\u6750\u6599\u300020\u682a\r\nRCB2986\u3000HCT116-MDC1(+\/-)  HCT11\u3000\u7d30\u80de\u4e9c\u682a\u3002MDC1\u907a\u4f1d\u5b50\u3092\u30d8\u30c6\u30ed\u6b20\u640d\u3002\u30df\u30b9\r\n\u3000\u3000\u3000\u3000\u3000\u30de\u30c3\u30c1\u4fee\u5fa9\u907a\u4f1d\u5b50\uff08hMLH1\uff09\u6b20\u640d\u3002\r\nRCB2987\u3000HCT116-MDC1(-\/-)  HCT116\u3000\u7d30\u80de\u4e9c\u682a\u3002MDC1\u907a\u4f1d\u5b50\u3092\u30db\u30e2\u6b20\u640d\uff08\u5b8c\u5168\r\n\u3000\u3000\u3000\u3000\u3000\u6b20\u640d\uff09\u3002\u30df\u30b9\u30de\u30c3\u30c1\u4fee\u5fa9\u907a\u4f1d\u5b50\uff08hMLH1\uff09\u6b20\u640d\u3002\r\nRCB2988\u3000HCT116-REV1(+\/-)  HCT116\u3000\u7d30\u80de\u4e9c\u682a\u3002REV1\u907a\u4f1d\u5b50\u3092\u30d8\u30c6\u30ed\u6b20\u640d\u3002\u30df\r\n\u3000\u3000\u3000\u3000\u3000\u30b9\u30de\u30c3\u30c1\u4fee\u5fa9\u907a\u4f1d\u5b50\uff08hMLH1\uff09\u6b20\u640d\u3002\r\nRCB2989\u3000HCT116-REV1(-\/-)  HCT116\u7d30\u80de\u4e9c\u682a\u3002REV1\u907a\u4f1d\u5b50\u3092\u30db\u30e2\u6b20\u640d\uff08\u5b8c\u5168\u6b20\r\n\u3000\u3000\u3000\u3000\u3000\u640d\uff09\u3002\u30df\u30b9\u30de\u30c3\u30c1\u4fee\u5fa9\u907a\u4f1d\u5b50\uff08hMLH1\uff09\u6b20\u640d\u3002\r\nRCB2990\u3000HCT116-REV3L(+\/-)  HCT116\u7d30\u80de\u4e9c\u682a\u3002REV3L\u907a\u4f1d\u5b50\u3092\u30d8\u30c6\u30ed\u6b20\u640d\u3002\u30df\r\n\u3000\u3000\u3000\u3000\u3000\u30b9\u30de\u30c3\u30c1\u4fee\u5fa9\u907a\u4f1d\u5b50\uff08hMLH1\uff09\u6b20\u640d\u3002\r\nRCB2991\u3000HCT116-Ku70(+\/-)  HCT116\u7d30\u80de\u4e9c\u682a\u3002Ku70\u907a\u4f1d\u5b50\u3092\u30d8\u30c6\u30ed\u6b20\u640d\u3002\u30df\u30b9\r\n\u3000\u3000\u3000\u3000\u3000\u30de\u30c3\u30c1\u4fee\u5fa9\u907a\u4f1d\u5b50\uff08hMLH1\uff09\u6b20\u640d\u3002\r\nRCB2992\u3000HCT116-DNAPKcs(+\/-)  HCT116\u7d30\u80de\u4e9c\u682a\u3002DNAPKcs\u907a\u4f1d\u5b50\u3092\u30d8\u30c6\u30ed\u6b20\u640d\u3002\r\n\u3000\u3000\u3000\u3000\u3000\u30df\u30b9\u30de\u30c3\u30c1\u4fee\u5fa9\u907a\u4f1d\u5b50\uff08hMLH1\uff09\u6b20\u640d\u3002\r\nRCB2993\u3000HCT116-POLM(+\/-)  HCT116\u7d30\u80de\u4e9c\u682a\u3002DNA polymerase m \u907a\u4f1d\u5b50\u3092\u30d8\u30c6\r\n\u3000\u3000\u3000\u3000\u3000\u30ed\u6b20\u640d\u3002\u30df\u30b9\u30de\u30c3\u30c1\u4fee\u5fa9\u907a\u4f1d\u5b50\uff08hMLH1\uff09\u6b20\u640d\u3002\r\nRCB2994\u3000HCT116-LIG3(+\/-)  HCT116\u7d30\u80de\u4e9c\u682a\u3002Ligase 3\u907a\u4f1d\u5b50\u3092\u30d8\u30c6\u30ed\u6b20\u640d\u3002\r\n\u3000\u3000\u3000\u3000\u3000\u30df\u30b9\u30de\u30c3\u30c1\u4fee\u5fa9\u907a\u4f1d\u5b50\uff08hMLH1\uff09\u6b20\u640d\u3002\r\nRCB2995\u3000HCT116-LIG4(+\/-)  HCT116\u7d30\u80de\u4e9c\u682a\u3002Ligase 4\u907a\u4f1d\u5b50\u3092\u30d8\u30c6\u30ed\u6b20\u640d\u3002\r\n\u3000\u3000\u3000\u3000\u3000\u30df\u30b9\u30de\u30c3\u30c1\u4fee\u5fa9\u907a\u4f1d\u5b50\uff08hMLH1\uff09\u6b20\u640d\u3002\r\nRCB2996\u3000HCT116-53BPI(+\/-)  HCT116\u7d30\u80de\u4e9c\u682a\u300253BPI\u907a\u4f1d\u5b50\u3092\u30d8\u30c6\u30ed\u6b20\u640d\u3002\u30df\r\n\u3000\u3000\u3000\u3000\u3000\u30b9\u30de\u30c3\u30c1\u4fee\u5fa9\u907a\u4f1d\u5b50\uff08hMLH1\uff09\u6b20\u640d\u3002\r\nRCB2997\u3000H414  HCT116\u7d30\u80de\u4e9c\u682a\u3002\u6b63\u5e38\u306a\u30df\u30b9\u30de\u30c3\u30c1\u4fee\u5fa9\u907a\u4f1d\u5b50\uff08hMLH1\uff09\u3092\u5fa9\u5143\r\n\u3000\u3000\u3000\u3000\u3000\u3057\u305f\u4e9c\u682a\u3002\r\nRCB2998\u3000H414-RAD18(+\/-)  H414\u7d30\u80de\u4e9c\u682a\u3002RAD18\u907a\u4f1d\u5b50\u3092\u30d8\u30c6\u30ed\u6b20\u640d\u3002\r\nRCB2999\u3000H414-RAD18(-\/-)  H414\u7d30\u80de\u4e9c\u682a\u3002RAD18\u907a\u4f1d\u5b50\u3092\u30db\u30e2\u6b20\u640d\uff08\u5b8c\u5168\u6b20\r\n\u3000\u3000\u3000\u3000\u3000\u640d\uff09\u3002\r\nRCB3000\u3000H414-MDC1(+\/-)  H414\u7d30\u80de\u4e9c\u682a\u3002MDC1\u907a\u4f1d\u5b50\u3092\u30d8\u30c6\u30ed\u6b20\u640d\u3002\r\nRCB3001\u3000H414-MDC1(-\/-)  H414\u7d30\u80de\u4e9c\u682a\u3002MDC1\u907a\u4f1d\u5b50\u3092\u30db\u30e2\u6b20\u640d\uff08\u5b8c\u5168\u6b20\u640d\uff09\u3002\r\nRCB3002\u3000H414-LIG4(+\/-)  H414\u7d30\u80de\u4e9c\u682a\u3002Ligase 4 \u907a\u4f1d\u5b50\u3092\u30d8\u30c6\u30ed\u6b20\u640d\u3002\r\nRCB3530\u3000B901L  \u30d2\u30c8\u80ba\u817a\u764c\u7531\u6765\u7d30\u80de\u682a\u3002\r\nRCB3531\u3000A904L  \u30d2\u30c8\u80ba\u5927\u7d30\u80de\u764c\u7531\u6765\u7d30\u80de\u682a\u3002\r\nRCB3532\u3000A129L  \u30d2\u30c8\u80ba\u817a\u764c\u7531\u6765\u7d30\u80de\u682a\u3002\r\n\r\n==========================================================\r\n\u25a0 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