{"id":10950,"date":"2018-03-08T23:27:12","date_gmt":"2018-03-08T14:27:12","guid":{"rendered":"http:\/\/cell.brc.riken.jp\/ja\/?page_id=10950"},"modified":"2026-01-19T13:55:53","modified_gmt":"2026-01-19T04:55:53","slug":"clinical_data_guidelines","status":"publish","type":"page","link":"http:\/\/cell.brc.riken.jp\/ja\/hps\/hps_diseaselist_index\/clinical_data_user_guidelines\/clinical_data_guidelines","title":{"rendered":"\u7406\u7814BRC\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5229\u7528\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3"},"content":{"rendered":"<p>\u56fd\u7acb\u7814\u7a76\u958b\u767a\u6cd5\u4eba\u7406\u5316\u5b66\u7814\u7a76\u6240\u30d0\u30a4\u30aa\u30ea\u30bd\u30fc\u30b9\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\uff08\u4ee5\u4e0b\u300c\u7406\u7814BRC\u300d\u3068\u3044\u3046\uff09\u306f\u3001\u672c\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306b\u5247\u3063\u3066\u30d2\u30c8iPS\u7d30\u80de\u306e\u4ed8\u968f\u60c5\u5831\u3068\u3057\u3066\u306e\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u306e\u5bc4\u8a17\u3092\u53d7\u3051\u3001\u307e\u305f\u3001\u30d2\u30c8iPS\u7d30\u80de\u306e\u63d0\u4f9b\u3068\u540c\u69d8\u306b\u3001\u5bc4\u8a17\u3092\u53d7\u3051\u305f\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u3092\u5229\u7528\u5e0c\u671b\u7814\u7a76\u8005\u306b\u63d0\u4f9b\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n<p>\u300c\u500b\u4eba\u60c5\u5831\u306e\u4fdd\u8b77\u306b\u95a2\u3059\u308b\u6cd5\u5f8b\u300d\uff08\u5e73\u621015 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href=\"https:\/\/humandbs.dbcls.jp\/guidelines\/data-sharing-guidelines\">\u300cNBDC\u30d2\u30c8\u30c7\u30fc\u30bf\u5171\u6709\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3 ver. 8.0\u300d<\/a>\u3092\u53c2\u8003\u306b\u3057\u3066\u5b9a\u3081\u305f\u3082\u306e\u3067\u3059\u3002<\/p>\n<p><strong>\u306f\u3058\u3081\u306b<\/strong><br 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\/>riken.jp<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n<p><strong>1.\u904b\u7528\u539f\u5247<\/strong><\/p>\n<p>(1)\u7406\u7814BRC\u304c\u5bc4\u8a17\u3092\u53d7\u3051\u305f\u3046\u3048\u3067\u5229\u7528\u5e0c\u671b\u8005\u306b\u63d0\u4f9b\u3059\u308b\u30d2\u30c8iPS\u7d30\u80de\u306b\u4ed8\u968f\u3059\u308b\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\uff08\u4ee5\u4e0b\u300c\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u300d\u3068\u3044\u3046\uff09\u306f\u3001\u4ee5\u4e0b\u306e\u539f\u5247\u306b\u57fa\u3065\u3044\u3066\u904b\u7528\u3055\u308c\u308b\u3002<br \/>\n\u3000\u3000\u539f\u52471\u3000\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u306f\u3001\u8981\u914d\u616e\u500b\u4eba\u60c5\u5831\u3068\u3057\u3066\u53d6\u308a\u6271\u3046<br 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\/>\n\u203b\u5177\u4f53\u7684\u306a\u8a18\u8ff0\u4f8b\u3092\u793a\u3059\u304c\u3001\u3053\u308c\u3089\u306b\u9650\u5b9a\u3055\u308c\u308b\u3082\u306e\u3067\u306f\u306a\u3044\u3002\uff08AMED\u63a8\u5968\u7248IC\u304b\u3089\u306e\u629c\u7c8b\uff09<\/p>\n<p>\u25c6\u540c\u610f\u6587\u66f8\u306b\u542b\u307e\u308c\u308b\u9805\u76ee<br \/>\n\u3010\u5fc5\u9808\u9805\u76ee\u8a18\u8ff0\u4f8b\u3011<\/p>\n<ul>\n<li>\u7406\u7814BRC\u3078\u306e\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u306e\u5bc4\u8a17\u3068\u591a\u6570\u306e\u7814\u7a76\u8005\u306b\u3088\u308b\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u306e\u5229\u7528<\/li>\n<\/ul>\n<p>\u25c6\u8aac\u660e\u6587\u66f8\u306b\u542b\u307e\u308c\u308b\u9805\u76ee<br \/>\n\u3010\u5fc5\u9808\u9805\u76ee\u8a18\u8ff0\u4f8b\u3011<\/p>\n<ul>\n<li>\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u3092\u7406\u7814BRC\u306b\u5bc4\u8a17\u3057\u3001\u591a\u6570\u306e\u7814\u7a76\u8005\u304c\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u3092\u5229\u7528\u3059\u308b\u3053\u3068<\/li>\n<p>\u5177\u4f53\u7684\u306a\u8a18\u8ff0\u4f8b\uff1a\u4eca\u5f8c\u3055\u3089\u306b\u7814\u7a76\u3092\u9032\u3081\u3066\u3044\u304f\u305f\u3081\u306b\u3082\u3001\u3042\u306a\u305f\u306e\u8840\u6db2\u7b49\u3068\u3001\u305d\u3053\u304b\u3089\u4f5c\u3063\u305fiPS\u7d30\u80de\u3092\u30ab\u30eb\u30c6\u60c5\u5831\u306a\u3069\u306e\u30c7\u30fc\u30bf\u3068\u4e00\u7dd2\u306b\u3001\u7406\u5316\u5b66\u7814\u7a76\u6240\u30d0\u30a4\u30aa\u30ea\u30bd\u30fc\u30b9\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\uff08\u4ee5\u4e0b\u3067\u306f\u300c\u7406\u7814BRC\u300d\u3068\u8a18\u8f09\u3057\u307e\u3059\uff09\u306b\u9001\u308a\u3001\u4eca\u5f8c\u3082\u6c38\u304f\u4fdd\u5b58\u3057\u3001\u56fd\u5185\u5916\u306e\u7814\u7a76\u8005\u306b\u914d\u5e03\u3055\u305b\u3066\u9802\u304d\u305f\u3044\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3069\u306e\u56fd\u306e\u7814\u7a76\u8005\u306b\u5bfe\u3057\u3066\u3082\u3001\u65e5\u672c\u56fd\u5185\u306e\u6cd5\u4ee4\u3084\u6307\u91dd\u306b\u6cbf\u3063\u3066\u4f5c\u6210\u3055\u308c\u305f\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u7b49\u306b\u6e96\u3058\u305f\u5229\u7528\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n<li>\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u3092\u4f01\u696d\u306b\u3082\u63d0\u4f9b\u3059\u308b\u3053\u3068<\/li>\n<p>\u5177\u4f53\u7684\u306a\u8a18\u8ff0\u4f8b\uff1a\u7406\u7814BRC\u306b\u4fdd\u5b58\u3055\u308c\u305f\u3042\u306a\u305f\u306e\u7d30\u80de\u3001\u4f5c\u88fd\u3055\u308c\u305fiPS\u7d30\u80de\u306f\u3001\u30ab\u30eb\u30c6\u3084\u300c\u81e8\u5e8a\u500b\u4eba\u8abf\u67fb\u7968\u300d\u304b\u3089\u5f97\u3089\u308c\u305f\u60c5\u5831\u306a\u3069\u3068\u3068\u3082\u306b\u3001\u56fd\u306e\u5b9a\u3081\u305f\u30eb\u30fc\u30eb\u306b\u57fa\u3065\u304d\u3001\u6b63\u5f0f\u306a\u624b\u7d9a\u304d\u3092\u7d4c\u305f\u3046\u3048\u3067\u3001\u65e5\u672c\u3084\u6d77\u5916\u306e\u7814\u7a76\u8005\u3084\u7814\u7a76\u6a5f\u95a2\uff08\u4f01\u696d\u306a\u3069\u3082\u542b\u3080\uff09\u306b\u914d\u3089\u308c\u3001\u75c5\u6c17\u306e\u89e3\u660e\u3084\u65b0\u3057\u3044\u85ac\u3084\u6cbb\u7642\u6cd5\u3092\u767a\u898b\u3059\u308b\u305f\u3081\u306b\u5e83\u304f\u5229\u7528\u3055\u305b\u3066\u304d\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3069\u306e\u56fd\u306e\u7814\u7a76\u8005\u306b\u5bfe\u3057\u3066\u3082\u3001\u65e5\u672c\u56fd\u5185\u306e\u6cd5\u4ee4\u3084\u6307\u91dd\u306b\u6cbf\u3063\u3066\u4f5c\u6210\u3055\u308c\u305f\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u7b49\u306b\u6e96\u3058\u305f\u5229\u7528\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n<li>\u7814\u7a76\u8005\u304c\u53d6\u5f97\u3057\u305f\u77e5\u7684\u8ca1\u7523\u6a29\u306f\u3001\u7814\u7a76\u3092\u5b9f\u65bd\u3057\u305f\u7814\u7a76\u8005\uff08\u7814\u7a76\u6a5f\u95a2\uff09\u306b\u5e30\u5c5e\u3059\u308b\u3053\u3068<\/li>\n<p>\u5177\u4f53\u7684\u306a\u8a18\u8ff0\u4f8b\uff1a\u3042\u306a\u305f\u306e\u8840\u6db2\u7b49\u304b\u3089\u4f5c\u3089\u308c\u305fiPS\u7d30\u80de\u3092\u7528\u3044\u305f\u7814\u7a76\u304c\u9032\u307f\u3001\u5c06\u6765\u753b\u671f\u7684\u306a\u767a\u898b\u304c\u3055\u308c\u305f\u5834\u5408\u3001\u305d\u3046\u3057\u305f\u767a\u898b\u306b\u81f3\u3063\u305f\u7814\u7a76\u8005\u3084\u7814\u7a76\u6a5f\u95a2\u306e\u82e6\u52b4\u306b\u5831\u3044\u308b\u305f\u3081\u306b\u3001\u7279\u8a31\u306a\u3069\u306e\u7279\u5225\u306a\u6a29\u5229\u304c\u8a8d\u3081\u3089\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\uff08\u3053\u308c\u3092\u300c\u77e5\u7684\u8ca1\u7523\u6a29\u300d\u3068\u3044\u3044\u307e\u3059\uff09\u3002\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001\u305d\u308c\u3089\u306e\u6a29\u5229\u306f\u7814\u7a76\u6a5f\u95a2\u5074\u306b\u5c5e\u3057\u3001\u3042\u306a\u305f\u306b\u5c5e\u3059\u308b\u3082\u306e\u3067\u306f\u306a\u3044\u3053\u3068\u3092\u3069\u3046\u305e\u3054\u7406\u89e3\u4e0b\u3055\u3044\u3002\n<\/p><\/ul>\n<p>\u3010\u542b\u307e\u308c\u308b\u3053\u3068\u304c\u671b\u307e\u3057\u3044\u9805\u76ee\u8a18\u8ff0\u4f8b\u3011<\/p>\n<ul>\n<li>\u7406\u7814BRC\u306b\u3064\u3044\u3066<\/li>\n<p>\u5177\u4f53\u7684\u306a\u8a18\u8ff0\u4f8b\uff1a\u7406\u7814BRC\u306f\u56fd\uff08\u6587\u90e8\u79d1\u5b66\u7701\uff09\u304b\u3089\u306e\u652f\u63f4\u3092\u53d7\u3051\u3066\u904b\u55b6\u3055\u308c\u3066\u3044\u308b\u6a5f\u95a2\u3067\u3001\u3053\u308c\u307e\u3067\u306b\u3082\u3059\u3067\u306b\u591a\u304f\u306e\u7814\u7a76\u7528iPS\u7d30\u80de\u3092\u96c6\u3081\u3066\u4fdd\u5b58\u3057\u3001\u65e5\u672c\u3084\u6d77\u5916\u306e\u591a\u304f\u306e\u7814\u7a76\u8005\u306b\u7d30\u80de\u3092\u914d\u5e03\u3057\u3066\u304d\u307e\u3057\u305f\u3002\u7406\u7814BRC\u306b\u306f\u3001\u7d30\u80de\u3092\u9069\u5207\u306a\u72b6\u614b\u3067\u4fdd\u7ba1\u3059\u308b\u305f\u3081\u306b\u5341\u5206\u306a\u4f53\u5236\u304c\u3042\u308a\u3001\u5fc5\u8981\u306a\u6280\u8853\u3092\u7fd2\u5f97\u3059\u308b\u305f\u3081\u306e<a href=\"https:\/\/web.brc.riken.jp\/ja\/training\">\u8b1b\u7fd2\u4f1a<\/a>\u3082\u958b\u50ac\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<li>\u305d\u306e\u4ed6<\/li>\n<\/ul>\n<p>\u3000\u3000\u300cAMED\u63a8\u5968\u7248IC\u3092\u53c2\u7167\u3059\u308b\u3053\u3068\uff08<a href=\"\/ja\/wp-content\/uploads\/clinical_data\/AMED_form_1.pdf\" target=\"_blank\" rel=\"noopener\">\u60a3\u8005\u3055\u3093\u3078\u306e\u8aac\u660e\u6587\u66f8<\/a>\u3001<a href=\"\/ja\/wp-content\/uploads\/clinical_data\/AMED_form_2.pdf\" target=\"_blank\" rel=\"noopener\">\u540c\u610f\u66f8\uff65\u540c\u610f\u64a4\u56de\u66f8<\/a>)\u300d<\/p>\n<p><strong>4-3.\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5bc4\u8a17\u306e\u624b\u9806<\/strong><br \/>\n\u5bc4\u8a17\u8005\u306f\u3001\u4e0b\u8a18\u306e\u624b\u9806<\/a>\u306b\u6cbf\u3063\u3066\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5bc4\u8a17\u306b\u95a2\u3059\u308b\u7533\u8acb\u3092\u884c\u3046\uff08\u30d2\u30c8iPS\u7d30\u80de\u305d\u306e\u3082\u306e\u306e\u5bc4\u8a17\u7533\u8acb\u3068\u540c\u6642\u3067\u3082\u5225\u9014\u3067\u3082\u3088\u3044\uff09\u3002<\/p>\n<ol>\n<li>\u5bc4\u8a17\u8005\u306f\u3001\u300c4-2.\u5bc4\u8a17\u8005\u306e\u8cac\u52d9\u300d\u306b\u793a\u3057\u3066\u3044\u308b\u8cac\u52d9\u3092\u6e80\u305f\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u78ba\u8a8d\u3059\u308b\u3002<\/li>\n<li>\u5bc4\u8a17\u8005\u306f\u3001\u975e\u5236\u9650\u516c\u958b\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u30fb\u5236\u9650\u516c\u958b\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u30fb\u516c\u958b\u5f85\u6a5f\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u306e\u9078\u629e\u3001\u304a\u3088\u3073\u3001\u516c\u958b\u5f85\u6a5f\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u306e\u5834\u5408\u306e\u516c\u958b\u6642\u671f\u306e\u8a2d\u5b9a\u7b49\u306b\u3064\u3044\u3066\u3001\u7406\u7814BRC\u3068\u8abf\u6574\u7b49\u3092\u884c\u3046\u3002<\/li>\n<li>\u5bc4\u8a17\u8005\u306f<a href=\"\/ja\/wp-content\/uploads\/clinical_data\/clinical_data_form_1.xls\" target=\"_blank\" rel=\"noopener\">\u300c\u30d2\u30c8iPS\u7d30\u80de\u306b\u4ed8\u968f\u3059\u308b\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u306e\u5bc4\u8a17\u7533\u8acb\u66f8\uff08\u69d8\u5f0f\uff11\uff09\u300d<\/a>\u3092\u7406\u7814BRC\u3078\u63d0\u51fa\u3059\u308b\u3002\u305d\u306e\u969b\u306b\u3001\u627f\u8a8d\u901a\u77e5\u66f8\u306e\u5199\u3057\u3001\u540c\u610f\u6587\u66f8\u30fb\u8aac\u660e\u6587\u66f8\u306e\u30d5\u30a9\u30fc\u30e0\u3001\u304a\u3088\u3073\u3001\u305d\u306e\u4ed6\u306e\u7406\u7814BRC\u304c\u6c42\u3081\u308b\u6587\u66f8\u3092\u6dfb\u4ed8\u3059\u308b\u3002<\/li>\n<li>\u7406\u7814BRC\u306f\u3001\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u306e\u5bc4\u8a17\u53d7\u5165\u308c\u306e\u53ef\u5426\u306b\u3064\u3044\u3066\u5be9\u67fb\u3059\u308b\u3002<\/li>\n<li>\u5bc4\u8a17\u8005\u306f\u3001\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u30d5\u30a1\u30a4\u30eb\uff08PDF\u30d5\u30a1\u30a4\u30eb\u7b49\uff09\u306e\u4f5c\u6210\u524d\u306b\u3001\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u304c\u533f\u540d\u5316\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u3092\u78ba\u8a8d\u306e\u3046\u3048\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u30d5\u30a1\u30a4\u30eb\uff08PDF\u30d5\u30a1\u30a4\u30eb\u7b49\uff09\u3092\u4f5c\u6210\u3057\u3001\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5185\u5305\u30e1\u30c7\u30a3\u30a2\u3092\u4f5c\u6210\u3059\u308b\u3002\u305f\u3060\u3057\u3001\u533f\u540d\u5316\u5f8c\u306e\u8a18\u53f7\u3092\u7528\u3044\u3066\u3001\u5404\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u304c\u3069\u306e\u30d2\u30c8iPS\u7d30\u80de\u306b\u4ed8\u968f\u3059\u308b\u3082\u306e\u304b\u306f\u5206\u304b\u308b\u72b6\u614b\u3067\u5bc4\u8a17\u3059\u308b\u3002\u307e\u305f\u3001\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5185\u5305\u30e1\u30c7\u30a3\u30a2\u306b\u30d1\u30b9\u30ef\u30fc\u30c9\u3092\u304b\u3051\u308b\u3002<\/li>\n<li>\u5bc4\u8a17\u8005\u306f\u3001\u7406\u7814BRC\u304c\u6307\u793a\u3059\u308b\u65b9\u6cd5\u306b\u5f93\u3063\u3066\u3001\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5185\u5305\u30e1\u30c7\u30a3\u30a2\u3092\u7406\u7814BRC\u306b\u9001\u4ed8\u3059\u308b\u3002\u5bc4\u8a17\u8005\u306f\u3001\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5185\u5305\u30e1\u30c7\u30a3\u30a2\u3068\u306f\u5225\u9014\u306b\u3001\u7b2c\u4e09\u8005\u306b\u95a2\u9023\u6027\u304c\u308f\u304b\u3089\u306a\u3044\u3088\u3046\u306b\u7406\u7814BRC\u306b\u30d1\u30b9\u30ef\u30fc\u30c9\u3092\u9001\u4ed8\u3059\u308b\u3002<\/li>\n<li>\u30a2\u30c3\u30d7\u30c7\u30fc\u30c8\u7b49\u306e\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u306e\u5909\u66f4\u306b\u3064\u3044\u3066\u306f\u3001\u5bc4\u8a17\u8005\u3068\u7406\u7814BRC\u3068\u306e\u5354\u8b70\u306b\u57fa\u3065\u304d\u3001\u5fc5\u8981\u306b\u5fdc\u3058\u3066\u5b9f\u65bd\u3059\u308b\u3002<\/li>\n<\/ol>\n<p><strong>5.\u5229\u7528\u306b\u3064\u3044\u3066<\/strong><\/p>\n<p><strong>5-1.\u5229\u7528\u8cc7\u683c<\/strong><\/p>\n<p>\u5236\u9650\u516c\u958b\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u306b\u95a2\u3057\u3066\u306f\u3001\u5229\u7528\u76ee\u7684\u3084\u5229\u7528\u5185\u5bb9\u306b\u95a2\u3057\u3066\u5229\u7528\u6a5f\u95a2\u7b49\u306b\u304a\u3051\u308b<a href=\"https:\/\/warp.ndl.go.jp\/info:ndljp\/pid\/13579820\/www.lifescience.mext.go.jp\/files\/pdf\/n2373_01.pdf\">\u300c\u4eba\u3092\u5bfe\u8c61\u3068\u3059\u308b\u751f\u547d\u79d1\u5b66\u30fb\u533b\u5b66\u7cfb\u7814\u7a76\u306b\u95a2\u3059\u308b\u502b\u7406\u6307\u91dd\u300d<\/a>\u3092\u9075\u5b88\u3057\u305f\u502b\u7406\u5be9\u67fb\u59d4\u54e1\u4f1a\u306e\u627f\u8a8d\u4e26\u3073\u306b\u5229\u7528\u6a5f\u95a2\u306e\u9577\u306e\u627f\u8a8d\u3092\u5f97\u305f\u5229\u7528\u8005\u306e\u307f\u304c\u5229\u7528\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3002<\/p>\n<p><strong>5-2.\u5229\u7528\u8005\u306e\u6a29\u5229<\/strong><\/p>\n<ol>\n<li>\u5229\u7528\u8005\u306f\u3001\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u3092\u5229\u7528\u3057\u305f\u7814\u7a76\u6210\u679c\u3092\u3001\u5229\u7528\u8005\u306e\u8cac\u52d9\u3092\u9075\u5b88\u3059\u308b\u9650\u308a\u81ea\u7531\u306b\u767a\u8868\u3067\u304d\u308b\u3002<\/li>\n<li>\u5229\u7528\u8005\uff08\u5229\u7528\u6a5f\u95a2\uff09\u306f\u3001\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u3092\u5229\u7528\u3057\u305f\u7814\u7a76\u7d50\u679c\u3092\u3082\u3068\u306b\u3057\u305f\u77e5\u7684\u8ca1\u7523\u6a29\u3092\u3001\u5229\u7528\u8005\u306e\u8cac\u52d9\u3092\u9075\u5b88\u3059\u308b\u9650\u308a\u81ea\u7531\u306b\u53d6\u5f97\u3067\u304d\u308b\u3002<\/li>\n<\/ol>\n<p><strong>5-3.\u5229\u7528\u8005\u306e\u8cac\u52d9<\/strong><br 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\/>\n\u3000\u5177\u4f53\u7684\u306a\u8a18\u8ff0\u4f8b\u3092\u793a\u3059\u304c\u3001\u3053\u308c\u306b\u9650\u5b9a\u3055\u308c\u308b\u3082\u306e\u3067\u306f\u306a\u3044\u3002<br \/>\n\u3010\u5fc5\u9808\u9805\u76ee\u8a18\u8ff0\u4f8b\u3011<br \/>\n\u3000\u7406\u7814BRC\u304c\u63d0\u4f9b\u3057\u3066\u3044\u308b\u30d2\u30c8iPS\u7d30\u80de\u306b\u4ed8\u968f\u3059\u308b\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u3092\u3001\u7406\u7814BRC\u304b\u3089\u5165\u624b\u3057\u3066\u3001\u672c\u7814\u7a76\u306b\u4f7f\u7528\u3059\u308b\u3002<\/p>\n<ol start=\"3\">\n<li>\u5229\u7528\u8005\u306f\u4e0b\u8a18\u306e\u4e8b\u9805\u3092\u9075\u5b88\u3059\u308b\u3002\n<ul>\n<li>\u5229\u7528\u306b\u3042\u305f\u3063\u3066\u9075\u5b88\u3059\u3079\u304d\u57fa\u672c\u7684\u4e8b\u9805\n<ul>\n<li>\u5229\u7528\u8005\u306e\u9650\u5b9a\uff08\u5229\u7528\u7533\u8acb\u3092\u3057\u305f\u7814\u7a76\u4ee3\u8868\u8005\u304a\u3088\u3073\u7814\u7a76\u4ee3\u8868\u8005\u3068\u540c\u4e00\u6a5f\u95a2\u306b\u6240\u5c5e\u3059\u308b\u7814\u7a76\u5206\u62c5\u8005\u306b\u9650\u308b\uff09<\/li>\n<li>\u5229\u7528\u76ee\u7684\u306e\u660e\u793a<\/li>\n<li>\u7533\u8acb\u3057\u305f\u5229\u7528\u76ee\u7684\u4ee5\u5916\u3067\u306e\u5229\u7528\u306e\u7981\u6b62<\/li>\n<li>\u7814\u7a76\u5229\u7528\u3078\u306e\u9650\u5b9a\uff08\u5275\u85ac\u7814\u7a76\u3092\u542b\u3080\uff09<\/li>\n<li>\u500b\u4eba\u540c\u5b9a\u306e\u7981\u6b62<\/li>\n<li>\u518d\u914d\u5e03\u306e\u7981\u6b62<\/li>\n<\/li>\n<\/ol>\n<ol start=\"4\">\n<li>\u5229\u7528\u8005\u306f\u3001\u300c\u7406\u7814BRC\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u53d6\u6271\u3044\u30bb\u30ad\u30e5\u30ea\u30c6\u30a3\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\uff08\u5225\u7d19\uff09\u300d\u3092\u9075\u5b88\u3057\u3001\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u3092\u5b89\u5168\u306b\u53d6\u308a\u6271\u3046\u3002\u307e\u305f\u3001\u5fc5\u8981\u6027\u306b\u5fdc\u3058\u3066\u3001\u7406\u7814BRC\u3042\u308b\u3044\u306f\u7406\u7814BRC\u304b\u3089\u4f9d\u983c\u3055\u308c\u305f\u7b2c\u4e09\u8005\u304c\u5b9f\u65bd\u3059\u308b\u30bb\u30ad\u30e5\u30ea\u30c6\u30a3\u5bfe\u7b56\u306e\u5b9f\u65bd\u72b6\u6cc1\u306b\u3064\u3044\u3066\u306e\u76e3\u67fb\u306b\u5fdc\u3058\u308b\u3002<\/li>\n<li>\u5229\u7528\u8005\u306f\u3001\u30bb\u30ad\u30e5\u30ea\u30c6\u30a3\u7ba1\u7406\u4f53\u5236\u3092\u69cb\u7bc9\u3059\u308b\u3002\u307e\u305f\u3001\u7406\u7814BRC\u304c\u63d0\u793a\u3059\u308b\u30bb\u30ad\u30e5\u30ea\u30c6\u30a3\u7ba1\u7406\u4f53\u5236\u306b\u9069\u5408\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u7406\u7814BRC\u3067\u5be9\u67fb\u3059\u308b\u305f\u3081\u3001\u5229\u7528\u7533\u8acb\u6642\u306b<a href=\"\/ja\/wp-content\/uploads\/clinical_data\/clinical_data_form_4.xls\" target=\"_blank\" rel=\"noopener\">\u300c\u5229\u7528\u7533\u8acb\u6642\u30c1\u30a7\u30c3\u30af\u30ea\u30b9\u30c8\uff08\u69d8\u5f0f\uff14\uff09\u300d<\/a>\u3092\u7406\u7814BRC\u3078\u63d0\u51fa\u3059\u308b\u3002<\/li>\n<li>\u5229\u7528\u8005\u306f\u3001\u4e07\u304c\u4e00\u3001\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u306e\u6f0f\u3048\u3044\u7b49\u306e\u30bb\u30ad\u30e5\u30ea\u30c6\u30a3\u306b\u95a2\u3059\u308b\u4e8b\u6545\u304c\u767a\u751f\u3057\u305f\u5834\u5408\u306b\u306f\u3001\u76f4\u3061\u306b\u81e8\u5e8a\u60c5\u5831\u5229\u7528\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u3092\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u304b\u3089\u5207\u308a\u96e2\u3059\u7b49\u306e\u8003\u3048\u5f97\u308b\u6700\u5584\u306e\u51e6\u7f6e\u3092\u5b9f\u65bd\u3057\u3001\u7406\u7814BRC\u306b\u5831\u544a\u3059\u308b\u3053\u3068\u3002\u305d\u306e\u5f8c\u306e\u4e8b\u6545\u51e6\u7406\u306b\u3064\u3044\u3066\u306f\u3001\u7406\u7814BRC\u306e\u6307\u793a\u306b\u5f93\u3044\u3001\u901f\u3084\u304b\u306b\u5b9f\u65bd\u3059\u308b\u3002<\/li>\n<li>\u5229\u7528\u8005\u306f\u3001\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u306e\u5229\u7528\u7d42\u4e86\u6642\u306b\u306f\u3001\u3059\u3079\u3066\u306e\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u3092\u7834\u68c4\u3057\u3001<a href=\"\/ja\/wp-content\/uploads\/clinical_data\/clinical_data_form_6.xls\" target=\"_blank\" rel=\"noopener\">\u300c\u5229\u7528\u7d42\u4e86\u5831\u544a\u66f8\uff08\u69d8\u5f0f\uff16\uff09\u300d<\/a>\u3092\u7528\u3044\u3066\u7834\u68c4\u306e\u5831\u544a\u3092\u7406\u7814BRC\u306b\u884c\u3046\u3002<\/li>\n<li>\u5229\u7528\u8005\u306f\u3001\u7406\u7814BRC\u304b\u3089\u5165\u624b\u3057\u305fiPS\u7d30\u80de\u304a\u3088\u3073\uff0f\u307e\u305f\u306f\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf<\/span>\u3092\u7528\u3044\u3066\u5f97\u3089\u308c\u305f\u7814\u7a76\u6210\u679c\u3092\u8ad6\u6587\u7b49\u3067\u516c\u8868\u3059\u308b\u969b\u306b\u306f\u3001\u4ee5\u4e0b\u306e\u5185\u5bb9\u3092\u8a18\u8ff0\u3059\u308b\u3002<\/li>\n<\/ol>\n<\/ul>\n<p>\u3010\u82f1\u6587\u8a18\u8f09\u4f8b\u3011\u25cb\u25cb\u25cb\u25cb\uff08\u7d30\u80de\u540d\uff09and their clinical information were provided by the RIKEN BRC through the National BioResource Project of the AMED, Japan.<\/p>\n<ol start=\"9\">\n<li>\u5229\u7528\u8005\u306f\u3001\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5229\u7528\u72b6\u6cc1\u306e\u516c\u958b\u306b\u3042\u305f\u308a\u3001\u7406\u7814BRC\u304c\u500b\u5225\u60c5\u5831\uff08\u5229\u7528\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u306e\u7531\u6765\u75be\u60a3\u540d\u3001\u5229\u7528\u8005\u6240\u5c5e\u6a5f\u95a2\u540d\u3001\u5229\u7528\u7814\u7a76\u4ee3\u8868\u8005\u6c0f\u540d\u3001\u5229\u7528\u958b\u59cb\u65e5\uff09\u3092\u516c\u8868\u3059\u308b\u3053\u3068\u306b\u3064\u3044\u3066\u4e86\u627f\u3059\u308b\u3002<\/li>\n<li>\u5229\u7528\u8005\u306f\u3001\u7406\u7814BRC\u304c\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5229\u7528\u72b6\u6cc1\u306e\u516c\u958b\u306b\u7528\u3044\u308b\u305f\u3081\u3001\u5229\u7528\u8005\u306e\u7533\u8acb\u6642\u304b\u3089\u5229\u7528\u7d42\u4e86\u5831\u544a\u6642\u306e\u60c5\u5831\u3001\u4e8b\u6545\u767a\u751f\u6642\u306e\u60c5\u5831\u7b49\u3001\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5229\u7528\u306b\u95a2\u3059\u308b\u60c5\u5831\u3092\u4fdd\u6301\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u4e86\u627f\u3059\u308b\u3002<\/li>\n<\/ol>\n<\/ul>\n<p>\u4ee5\u4e0a\u306e\u5185\u5bb9\u306b\u3064\u3044\u3066\u9055\u53cd\u304c\u8a8d\u3081\u3089\u308c\u305f\u5834\u5408\u306f\u5229\u7528\u306e\u8a31\u53ef\u3092\u53d6\u308a\u6d88\u3057\u3001\u9055\u53cd\u306e\u4e8b\u5b9f\u3092\u30a6\u30a7\u30d6\u30b5\u30a4\u30c8\u7b49\u3067\u516c\u8868\u3059\u308b\u3053\u3068\u304c\u3042\u308b\u3002\u307e\u305f\u3001\u4ee5\u4e0a\u306e\u5185\u5bb9\u306f\u5168\u3066\u306e\u5229\u7528\u8005\u306b\u9069\u7528\u3055\u308c\u3001\u7814\u7a76\u4ee3\u8868\u8005\u306f\u5168\u3066\u306e\u5229\u7528\u8005\u304c\u672c\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u304a\u3088\u3073\u300c\u7406\u7814BRC\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u53d6\u6271\u3044\u30bb\u30ad\u30e5\u30ea\u30c6\u30a3\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\uff08\u5225\u7d19\uff09\u300d\u3092\u9075\u5b88\u3059\u308b\u3053\u3068\u306b\u5bfe\u3057\u3066\u8cac\u4efb\u3092\u6301\u3064\u3082\u306e\u3068\u3059\u308b\u3002<\/p>\n<p><strong>5-4.\u5229\u7528\u306e\u624b\u9806<\/strong><br \/>\n\u5229\u7528\u8005\u306f\u3001\u672c\u624b\u9806<\/a>\u306b\u6cbf\u3063\u3066\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5229\u7528\u7533\u8acb\u3092\u884c\u3046\u3002\u3053\u306e\u6642\u3001\u5225\u7d44\u7e54\u306b\u6240\u5c5e\u3059\u308b\u8907\u6570\u306e\u7814\u7a76\u8005\u304c\u5171\u540c\u7814\u7a76\u3092\u884c\u3046\u5834\u5408\u306f\u3001\u305d\u308c\u305e\u308c\u306e\u7d44\u7e54\u6bce\u306b\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5229\u7528\u7533\u8acb\u3092\u884c\u3046\u3002<\/p>\n<ol>\n<li>\u5229\u7528\u8005\u306f\u3001\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u306e\u5229\u7528\u306b\u95a2\u9023\u3057\u3066\u3001\u6240\u5c5e\u6a5f\u95a2\u7b49\u306e\u502b\u7406\u5be9\u67fb\u59d4\u54e1\u4f1a\u306e\u627f\u8a8d\u4e26\u3073\u306b\u6240\u5c5e\u6a5f\u95a2\u306e\u9577\u306e\u627f\u8a8d\u3092\u5f97\u3066\u3044\u308b\u4e8b\u3092\u793a\u3059\u66f8\u9762\u306e\u5199\u3057\u3092\u3001\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5229\u7528\u7533\u8acb\u306e\u969b\u306b\u63d0\u51fa\u3059\u308b\u3002<\/li>\n<li>\u5229\u7528\u8005\u306f\u3001\u5229\u7528\u7533\u8acb\u306b\u969b\u3057\u3066\u3001<a href=\"\/ja\/wp-content\/uploads\/clinical_data\/clinical_data_form_2.xls\" target=\"_blank\" rel=\"noopener\">\u300c\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf<\/span>\u306e\u5229\u7528\u7533\u8acb\u66f8\uff08\u69d8\u5f0f\uff12\uff09\u300d<\/a>\u3001<a href=\"\/ja\/wp-content\/uploads\/clinical_data\/clinical_data_form_4.xls\" target=\"_blank\" rel=\"noopener\">\u300c\u5229\u7528\u7533\u8acb\u6642\u30c1\u30a7\u30c3\u30af\u30ea\u30b9\u30c8\uff08\u69d8\u5f0f\uff14\uff09\u300d<\/a>\u3001<a href=\"\/ja\/wp-content\/uploads\/clinical_data\/clinical_data_form_5.docx\" target=\"_blank\" rel=\"noopener\">\u300c\u7814\u7a76\u8a08\u753b\u66f8\u629c\u7c8b\u66f8\uff08\u69d8\u5f0f\uff15\uff09\u300d<\/a>\u3001\u5fc5\u8981\u306b\u5fdc\u3058\u3066<a href=\"\/ja\/wp-content\/uploads\/clinical_data\/clinical_data_form_3.xls\" target=\"_blank\" rel=\"noopener\">\u300c\u5229\u7528\u7814\u7a76\u5206\u62c5\u8005\u4e00\u89a7\uff08\u69d8\u5f0f\uff13\uff09\u300d<\/a>\u3001\u305d\u306e\u4ed6\u7406\u7814BRC\u304c\u6c42\u3081\u308b\u60c5\u5831\u3084\u8cc7\u6599\u3092\u63d0\u51fa\u3059\u308b\u3002<\/li>\n<li>\u7406\u7814BRC\u306f\u3001\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u306e\u5229\u7528\u306e\u53ef\u5426\u306b\u3064\u3044\u3066\u5be9\u67fb\u3059\u308b\u3002<\/li>\n<li>\u7406\u7814BRC\u306b\u3088\u308a\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5229\u7528\u7533\u8acb\u304c\u627f\u8a8d\u3055\u308c\u305f\u5f8c\u306b\u3001\u7406\u7814BRC\u304b\u3089\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u304c\u63d0\u4f9b\u3055\u308c\u308b\u3002\u7406\u7814BRC\u304c\u63d0\u4f9b\u7528\u306e\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5185\u5305\u30e1\u30c7\u30a3\u30a2\u3092\u4f5c\u6210\u3057\u3066\u7814\u7a76\u4ee3\u8868\u8005\u306b\u9001\u4ed8\u3059\u308b\u3002<\/li>\n<li>\u5229\u7528\u8005\u306f\u3001\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u306e\u5229\u7528\u304c\u7d42\u4e86\u3057\u305f\u5834\u5408\u3001\u3042\u308b\u3044\u306f\u300c\uff15\uff0d\uff16\uff0e\u5229\u7528\u306e\u505c\u6b62\u300d\u306b\u8a72\u5f53\u3057\u3001\u7406\u7814BRC\u306b\u3088\u308a\u5229\u7528\u304c\u505c\u6b62\u3055\u308c\u305f\u5834\u5408\u3001\u901f\u3084\u304b\u306b\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u3092\u7834\u68c4\u3057\u3001<a href=\"\/ja\/wp-content\/uploads\/clinical_data\/clinical_data_form_6.xls\" target=\"_blank\" rel=\"noopener\">\u300c\u5229\u7528\u7d42\u4e86\u5831\u544a\u66f8\uff08\u69d8\u5f0f\uff16\uff09\u300d<\/a>\u3092\u7528\u3044\u3066\u3001\u7406\u7814BRC\u3078\u7834\u68c4\u306e\u5831\u544a\u3092\u884c\u3046\u3002<\/li>\n<li>\u5f53\u521d\u306e\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5229\u7528\u671f\u9593\u3092\u8d85\u3048\u3066\u5f53\u8a72\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u306e\u5229\u7528\u3092\u5e0c\u671b\u3059\u308b\u5834\u5408\u306b\u306f\u3001\u5f53\u8a72\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5229\u7528\u671f\u9593\u6e80\u4e86\u306e\u4e00\u30f6\u6708\u524d\u307e\u3067\u306b\u3001\u6240\u5c5e\u6a5f\u95a2\u7b49\u306e\u502b\u7406\u5be9\u67fb\u59d4\u54e1\u4f1a\u306e\u627f\u8a8d\u901a\u77e5\u66f8\u7b49\uff08\u627f\u8a8d\u3055\u308c\u305f\u7814\u7a76\u671f\u9593\u304c\u308f\u304b\u308b\u66f8\u985e\uff09\u3068\u5171\u306b<a href=\"\/ja\/wp-content\/uploads\/clinical_data\/clinical_data_form_7.docx\" target=\"_blank\" rel=\"noopener\">\u300c\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5229\u7528\u671f\u9593\u5ef6\u9577\u7533\u8acb\u66f8\uff08\u69d8\u5f0f\uff17\uff09\u300d<\/a>\u3092\u7406\u7814BRC\u306b\u63d0\u51fa\u3059\u308b\u3053\u3068\u3067\u3001\u5f53\u8a72\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5229\u7528\u306e\u671f\u9593\u5ef6\u9577\u7533\u8acb\u3068\u3059\u308b\u3002<\/li>\n<li>\u5229\u7528\u8005\u306f\u3001\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5185\u5305\u30e1\u30c7\u30a3\u30a2\u304c\u7834\u640d\u3057\u3066\u3057\u307e\u3063\u305f\u5834\u5408\u306b\u306f\u3001\u7406\u7814BRC\u304b\u3089\u306e\u518d\u63d0\u4f9b\u3092\u53d7\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3002\u305d\u306e\u969b\u3001\u7814\u7a76\u4ee3\u8868\u8005\u306f\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5185\u5305\u30e1\u30c7\u30a3\u30a2\u3092\u5b8c\u5168\u306b\u518d\u5229\u7528\u4e0d\u80fd\u306a\u72b6\u614b\u306b\u7834\u58ca\u3057\u3066\u5ec3\u68c4\u3057\u305f\u4e0a\u3067\u3001<a href=\"\/ja\/wp-content\/uploads\/clinical_data\/clinical_data_form_8.docx\" target=\"_blank\" rel=\"noopener\">\u300c\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u5185\u5305\u30e1\u30c7\u30a3\u30a2\u518d\u63d0\u4f9b\u4f9d\u983c\u66f8\uff08\u69d8\u5f0f\uff18\uff09\u300d<\/a>\u3092\u7528\u3044\u3066\u3001\u7406\u7814BRC\u306b\u518d\u63d0\u4f9b\u3092\u4f9d\u983c\u3059\u308b\u3002<\/li>\n<\/ol>\n<p><strong>5-5.\u5229\u7528\u306b\u95a2\u3059\u308b\u8cbb\u7528<\/strong><br \/>\n\u7406\u7814iPS\u81e8\u5e8a\u60c5\u5831\u30c7\u30fc\u30bf\u306e\u5229\u7528\u306b\u969b\u3057\u3066\u5b9f\u8cbb\u304c\u767a\u751f\u3059\u308b\u5834\u5408\uff08\u30e1\u30c7\u30a3\u30a2\u4ee3\u3001\u8f38\u9001\u8cbb\u7b49\uff09\u306f\u5229\u7528\u8005\u306e\u8ca0\u62c5\u3068\u3059\u308b\u3002<\/p>\n<p><strong>5-6.\u5229\u7528\u306e\u505c\u6b62<\/strong><br 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