{"id":11408,"date":"2026-10-08T09:07:57","date_gmt":"2026-10-08T00:07:57","guid":{"rendered":"http:\/\/cell.brc.riken.jp\/en\/?page_id=11408"},"modified":"2026-10-08T09:07:57","modified_gmt":"2026-10-08T00:07:57","slug":"mn20261008","status":"publish","type":"page","link":"http:\/\/cell.brc.riken.jp\/en\/mail_news\/mn20261008","title":{"rendered":"RIKEN BRC Cell Bank MAILNEWS 2026.10.08"},"content":{"rendered":"<pre>\r\n*******************************************\r\nRIKEN BioResource Research Center Cell Bank\r\n   MAILNEWS 20261008\r\n<a href=\"\/en\/\">https:\/\/cell.brc.riken.jp\/en\/<\/a>\r\n*******************************************\r\nRIKEN BioResource Research Center (BRC) is pleased to update you with\r\nthe latest information.\r\n\r\n====Contents========================\r\n\uff65 Newly cataloged cell lines (2026.10)\r\n\uff65 User publications\r\n\uff65 Guidance on Depositing or Transferring Cell Materials\r\n\uff65 For Those Considering Depositing Cell Materials\r\n\uff65 Editor's note\r\n===================================\r\nWe hope you find the contents of this message of interest.\r\nHowever, if you would prefer to unsubscribe from future e-mails,\r\nplease send an e-mail to <a href=\"mailto:&#99;&#101;l&#108;b&#x61;nk.b&#x72;c&#x40;r&#105;ken&#46;&#x6a;&#112;\">cellbank.brc<img loading=\"lazy\" decoding=\"async\" title=\"\" alt=\"\" src=\"\/ja\/wp-content\/uploads\/images\/at.png\" width=\"13\" height=\"13\" \/>riken.jp<\/a>.\r\n\r\n===================================\r\n\uff65 Newly cataloged cell lines (2026.10)\r\n===================================\r\nFor more details, please refer to the link below.\r\n\r\n<a href=\"\/en\/new_resource\">https:\/\/cell.brc.riken.jp\/en\/new_resource<\/a>\r\n\r\n===================================\r\n\uff65 User publications\r\n===================================\r\nResearch findings using A-6 (RCB1517), a hematopoietic progenitor cell\r\nline established from the mouse ES cell line AES0001 (H-1) available\r\nfrom our Cell Bank, have recently been published.\r\nMechanism Underlying Hematopoietic Stem Cell Self-Renewal Uncovered:\r\nPotential Application to Ex Vivo Expansion of Hematopoietic Stem\r\nCells \u2013 Kumamoto University\r\n<a href=\"https:\/\/ircms.kumamoto-u.ac.jp\/publications\/2026\/09\/suppressing-glutamate-dehydrogenase-guides-hematopoietic-stem-cell-divisions-into-self-r.html\">https:\/\/ircms.kumamoto-u.ac.jp\/publications\/2026\/09\/suppressing-glutamate-dehydrogenase-guides-hematopoietic-stem-cell-divisions-into-self-r.html<\/a>\r\n\r\nA-6 (RCB1517) is a cell line established from the mouse ES cell line\r\nAES0001 (H-1). Upon stimulation with SCF (Stem Cell Factor), A-6 cells\r\ncan differentiate into erythroid cells, neutrophils, and macrophages.\r\nMultipotent hematopoietic progenitor cell lines such as A-6 are valuable\r\nand have been used in research on hematopoietic stem cells.\r\nRecently, research findings obtained using this cell line were published\r\nin a scientific journal:\r\n<a href=\"https:\/\/www.nature.com\/articles\/s41467-026-77151-6\">https:\/\/www.nature.com\/articles\/s41467-026-77151-6<\/a>\r\nThe study demonstrated that inhibition of glutamate dehydrogenase and\r\nactivation of the JAK-STAT pathway promote the self-renewal of mouse\r\nhematopoietic stem cells. These findings are expected to contribute to\r\nthe future development of technologies for the ex vivo expansion of\r\nhematopoietic stem cells.\r\n\r\nPress Releases and Media Coverage\r\n<a href=\"\/ja\/report\">https:\/\/cell.brc.riken.jp\/ja\/report<\/a>\r\n\r\n===================================\r\n\uff65 Guidance on Depositing or Transferring Cell Materials\r\n===================================\r\nThe RIKEN BRC Cell Engineering Division accepts deposits\r\nand transfers of newly developed cell materials. If you have\r\nestablished a new cell line, we encourage you to consider\r\ndepositing or transferring it to our division.\r\n<a href=\"https:\/\/web.brc.riken.jp\/en\/requests\/deposit\">https:\/\/web.brc.riken.jp\/en\/requests\/deposit<\/a>\r\n\r\nWhen submitting materials, we ask for confirmation of any\r\nintellectual property associated with the cell line. This\r\nincludes licenses related to technologies used during cell line\r\nestablishment, as well as licenses for the original (parent) cell\r\nline in the case of modified or derivative lines. Additional\r\ninformation may be requested as needed. Please note that\r\nthese confirmation procedures may require some time before\r\nthe deposited cells can be accepted.\r\n\r\nFurthermore, RIKEN BRC has reached agreements regarding the\r\ndeposit and distribution of the following bioresources:\r\n\uff65 Demeetra AgBio, Inc.: bioresources containing the piggyBac(R)\r\n  transposon\r\n\uff65 InvivoGen: bioresources containing the Zeocin resistance gene\r\n  and\/or GFP::bsr \r\nPlease see the details below.\r\n<a href=\"https:\/\/web.brc.riken.jp\/en\/method\/link\">https:\/\/web.brc.riken.jp\/en\/method\/link<\/a>\r\n\r\n===================================\r\n\uff65 For Those Considering Depositing Cell Materials\r\n===================================\r\nCell vials deposited with us are temporarily stored in the\r\nvapor phase of liquid nitrogen (-196\u00b0C). To ensure safety and\r\nmaintain cell quality, we kindly ask that you use cryovials\r\nsuitable for liquid nitrogen storage when preparing materials\r\nfor deposit.\r\nGeneral microtubes designed for -80\u00b0C storage may:\r\n\uff65 rupture when exposed to liquid nitrogen\r\n\uff65 fail to maintain appropriate storage conditions, potentially\r\ncompromising cell quality.\r\nFor these reasons, please refrain from using such tubes.\r\n\r\n===================================\r\n\uff65 Editor's note\r\n===================================\r\nIn Japan, this time of year marks the gradual transition into autumn,\r\na season often associated with reflection and a renewed sense of rhythm.\r\nAs we move into the latter half of the fiscal year, it is a natural\r\nmoment to look back on our progress and consider the work that lies\r\nahead.\r\nFollowing the release of this MAILNEWS, the BRC Open House will take\r\nplace. As a valuable opportunity for visitors to learn more about the\r\nactivities of the RIKEN Cell Bank, we are steadily preparing for the\r\nevent and look forward to welcoming participants.\r\nWishing you well during this period of transition. K.N.\r\n===================================\r\n*If you have any questions or comments, please send an e-mail to\r\n<a href=\"mailto:&#99;&#101;l&#108;b&#x61;nk.b&#x72;c&#x40;r&#105;ken&#46;&#x6a;&#112;\">cellbank.brc<img loading=\"lazy\" decoding=\"async\" title=\"\" alt=\"\" src=\"\/ja\/wp-content\/uploads\/images\/at.png\" width=\"13\" height=\"13\" \/>riken.jp<\/a>.\r\n*Content is subject to change without notice.\r\n*All Rights Reserved.\r\n_________________________________________\r\nRIKEN BioResource Research Center Cell Bank\r\n3-1-1 Koyadai, Tsukuba,\r\nIbaraki, 305-0074, Japan\r\n<a href=\"mailto:&#99;&#101;l&#108;b&#x61;nk.b&#x72;c&#x40;r&#105;ken&#46;&#x6a;&#112;\">cellbank.brc<img loading=\"lazy\" decoding=\"async\" title=\"\" alt=\"\" src=\"\/ja\/wp-content\/uploads\/images\/at.png\" width=\"13\" height=\"13\" \/>riken.jp<\/a>\r\n<a href=\"\/en\/\">https:\/\/cell.brc.riken.jp\/en\/<\/a>\r\n<a href=\"https:\/\/x.com\/RIKEN_BRC_en\">https:\/\/x.com\/RIKEN_BRC_en<\/a>\r\n_________________________________________\r\n2026.10.08\r\n<\/pre>\n","protected":false},"excerpt":{"rendered":"<p>******************************************* RIKEN BioResource Research Center Cell Bank MAILNEWS 20261008 https:\/\/cell.brc.riken.jp\/en\/ ******************************************* RIKEN BioResource Research Center (BRC) is pleased to update you with the latest information. ====Contents======================== \uff65 Newly cataloged cell lines (2026.10) \uff65 User publications \uff65 Guidance on Depositing or Transferring Cell Materials \uff65 For Those Considering Depositing Cell Materials \uff65 Editor&#8217;s note =================================== We hope you find the contents of this message of interest. However, if you would prefer to unsubscribe from future e-mails, please send an e-mail to cellbank.brcriken.jp. =================================== \uff65 Newly cataloged cell lines (2026.10) =================================== For more details, please refer to the link below. https:\/\/cell.brc.riken.jp\/en\/new_resource =================================== \uff65 User publications =================================== Research findings using A-6 (RCB1517), a hematopoietic progenitor cell line established from the mouse ES cell line AES0001 (H-1) available from our Cell Bank, have recently been published. Mechanism Underlying Hematopoietic Stem Cell Self-Renewal Uncovered: Potential Application to Ex Vivo Expansion of Hematopoietic Stem Cells \u2013 Kumamoto University https:\/\/ircms.kumamoto-u.ac.jp\/publications\/2026\/09\/suppressing-glutamate-dehydrogenase-guides-hematopoietic-stem-cell-divisions-into-self-r.html A-6 (RCB1517) is a cell line established from the mouse ES cell line AES0001 (H-1). Upon stimulation with SCF (Stem Cell Factor), A-6 cells can differentiate into erythroid cells, neutrophils, and macrophages. Multipotent hematopoietic progenitor cell lines such as A-6 are valuable and have been used in [&hellip;]<\/p>\n","protected":false},"author":14,"featured_media":0,"parent":8973,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_seopress_robots_follow":"","_seopress_robots_imageindex":"","_seopress_robots_snippet":"","_seopress_robots_primary_cat":"","_seopress_robots_breadcrumbs":"","_seopress_robots_freeze_modified_date":"","_seopress_robots_custom_modified_date":"","_seopress_robots_canonical":"","_seopress_social_fb_title":"","_seopress_social_fb_desc":"","_seopress_social_fb_img":"","_seopress_social_fb_img_attachment_id":0,"_seopress_social_fb_img_width":0,"_seopress_social_fb_img_height":0,"_seopress_social_twitter_title":"","_seopress_social_twitter_desc":"","_seopress_social_twitter_img":"","_seopress_social_twitter_img_attachment_id":0,"_seopress_social_twitter_img_width":0,"_seopress_social_twitter_img_height":0,"_seopress_redirections_value":"","_seopress_redirections_enabled":"","_seopress_redirections_enabled_regex":"","_seopress_redirections_logged_status":"","_seopress_redirections_param":"","_seopress_redirections_type":0,"_seopress_analysis_target_kw":"","footnotes":"","_wp_rev_ctl_limit":""},"class_list":["post-11408","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/cell.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/11408","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/cell.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/cell.brc.riken.jp\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/cell.brc.riken.jp\/en\/wp-json\/wp\/v2\/users\/14"}],"replies":[{"embeddable":true,"href":"http:\/\/cell.brc.riken.jp\/en\/wp-json\/wp\/v2\/comments?post=11408"}],"version-history":[{"count":1,"href":"http:\/\/cell.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/11408\/revisions"}],"predecessor-version":[{"id":11409,"href":"http:\/\/cell.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/11408\/revisions\/11409"}],"up":[{"embeddable":true,"href":"http:\/\/cell.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/8973"}],"wp:attachment":[{"href":"http:\/\/cell.brc.riken.jp\/en\/wp-json\/wp\/v2\/media?parent=11408"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}