{"id":10498,"date":"2023-02-02T16:42:05","date_gmt":"2023-02-02T07:42:05","guid":{"rendered":"http:\/\/cell.brc.riken.jp\/en\/?page_id=10498"},"modified":"2026-04-15T13:59:13","modified_gmt":"2026-04-15T04:59:13","slug":"brc-resource-news","status":"publish","type":"page","link":"http:\/\/cell.brc.riken.jp\/en\/brc-resource-news","title":{"rendered":"BRC RESOURCE NEWS"},"content":{"rendered":"<p><a href=\"https:\/\/web.brc.riken.jp\/en\/r_n\">BRC RESOURCE NEWS Archive<\/a><br \/>\n\n<table id=\"tablepress-184\" class=\"tablepress tablepress-id-184\">\n<thead>\n<tr class=\"row-1\">\n\t<th class=\"column-1\">VOL<\/th><th class=\"column-2\">Title<\/th>\n<\/tr>\n<\/thead>\n<tbody class=\"row-striping row-hover\">\n<tr class=\"row-2\">\n\t<td class=\"column-1\">2026 vol.12<\/td><td class=\"column-2\"><a href=\"#vol12\">FY2026 Training course for human iPS cells<\/a><\/td>\n<\/tr>\n<tr class=\"row-3\">\n\t<td class=\"column-1\">2026 vol.11<\/td><td class=\"column-2\"><a href=\"#vol11\">We have a large collection of animal cell lines<\/a><\/td>\n<\/tr>\n<tr class=\"row-4\">\n\t<td class=\"column-1\">2025 vol.10<\/td><td class=\"column-2\"><a href=\"#vol10\">FY2025 Training course for human iPS cells<\/a><\/td>\n<\/tr>\n<tr class=\"row-5\">\n\t<td class=\"column-1\">2024 vol.09<\/td><td class=\"column-2\"><a href=\"#vol9\">We are looking for the requests from users of human iPS cells.<\/a><\/td>\n<\/tr>\n<tr class=\"row-6\">\n\t<td class=\"column-1\">2024 vol.08<\/td><td class=\"column-2\"><a href=\"#vol8\">Attention to commonly used cell lines<\/a><\/td>\n<\/tr>\n<tr class=\"row-7\">\n\t<td class=\"column-1\">2024 vol.07<\/td><td class=\"column-2\"><a href=\"https:\/\/web.brc.riken.jp\/en\/training\/\">FY2024 Training course for human iPS cells<\/a><\/td>\n<\/tr>\n<tr class=\"row-8\">\n\t<td class=\"column-1\">2024 vol.06<\/td><td class=\"column-2\"><a href=\"#vol6\">We are looking for the following requests from users of human iPS cells<\/a><\/td>\n<\/tr>\n<tr class=\"row-9\">\n\t<td class=\"column-1\">2023 vol.05<\/td><td class=\"column-2\"><a href=\"#vol5\">Information of genetic analyses regarding disease-specific iPS cells<\/a><\/td>\n<\/tr>\n<tr class=\"row-10\">\n\t<td class=\"column-1\">2023 vol.04<\/td><td class=\"column-2\"><a href=\"https:\/\/web.brc.riken.jp\/en\/training\/\">FY2023 Training course for human iPS cells<\/a><\/td>\n<\/tr>\n<tr class=\"row-11\">\n\t<td class=\"column-1\">2022 vol.03<\/td><td class=\"column-2\"><a href=\"#vol3\">Reporter knock-in iPS cell lines<\/a><\/td>\n<\/tr>\n<tr class=\"row-12\">\n\t<td class=\"column-1\">2022 vol.02<\/td><td class=\"column-2\"><a href=\"#vol2\">Human iPS cells derived from patients and healthy individuals<\/a><\/td>\n<\/tr>\n<tr class=\"row-13\">\n\t<td class=\"column-1\">2022 vol.01<\/td><td class=\"column-2\"><a href=\"#vol1\">Cell line resources for COVID-19 related research<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<!-- #tablepress-184 from cache -->\n<a name=\"vol12\"><\/a><\/p>\n<hr \/>\n<h5>FY2026 Training course for human iPS cells<\/h5>\n<p>The training course for human iPS cells will be held. In this course, we will offer a lecture and practical training for human iPS cells including the overview of human iPS cell culture methods with passaging, freezing and resuscitation on feeder cells (vitrification method) as well as feeder-free culture methods in 1 day course.<br \/>\nPlease refer to our webpage for more information.<br \/>\n<a href=\"https:\/\/web.brc.riken.jp\/en\/training\">https:\/\/web.brc.riken.jp\/en\/training<\/a><\/p>\n<div class=\"gazo\">\n<img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/images\/r_n12_cell_01.webp\" alt=\"ips_training_2026_1\" width=\"300px\"><\/a><\/p>\n<\/div>\n<div class=\"gazo\">\n<img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/images\/r_n12_cell_02.webp\" alt=\"ips_training_2026_2\"  width=\"300px\"><\/a><\/p>\n<\/div>\n<p><a name=\"vol11\"><\/a><\/p>\n<hr \/>\n<h5>We have a large collection of animal cell lines<\/h5>\n<p>Our cell bank provides a wide range of animal cell lines for diverse research needs. Currently, we hold cell lines from about 40 animal species, including mink, enabling researchers to conveniently access the cells they require in one place.<br \/>\n<img decoding=\"async\" src=\"\/en\/wp-content\/uploads\/images\/RCB1833.jpg\"alt=\" Mink\"><br \/>\nMink\uff08<a href=\"https:\/\/cellbank.brc.riken.jp\/cell_bank\/CellInfo\/?cellNo=RCB1833&#038;lang=En\">RCB1833<\/a>\uff09<\/a><\/p>\n<p><a name=\"vol10\"><\/a><\/p>\n<hr \/>\n<h5>FY2025 Training course for human iPS cells<\/h5>\n<p>The training course for human iPS cells will be held. In this course, we will offer a lecture and practical training for human iPS cells including the overview of human iPS cell culture methods with passaging, freezing and resuscitation on feeder cells (vitrification method) as well as feeder-free culture methods in 1 day course.<br \/>\nPlease refer to our webpage for more information.<br \/>\n<a href=\"https:\/\/web.brc.riken.jp\/en\/training\">https:\/\/web.brc.riken.jp\/en\/training<\/a><br \/>\n<img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/images\/training2025.jpg\" alt=\"ips_training_2025\" width=\"300px\"><\/a><\/p>\n<p><a name=\"vol9\"><\/a><\/p>\n<hr \/>\n<h5>We are looking for the requests from users of human iPS cells.<\/h5>\n<ul>\n<li>Generation of a cell line in which a specific gene deletion (knockout) or a specific gene mutation is introduced in the iPS cells derived from healthy individuals etc.<\/li>\n<li>Repair of a causal gene mutation in certain disease-specific iPS cell line.<\/li>\n<li>Adding whole genome information to the cell lines of the disease of your interest.<\/li>\n<\/ul>\n<div class=\"gazo\">\n<img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/images\/feeder_free_9.jpg\" alt=\"On-feeder\" width=\"300px\"><\/p>\n<p>Healthy donor-derived iPS cells (Left: On-feeder Right: Feeder-free)<\/p>\n<\/div>\n<div class=\"gazo\">\n<img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/images\/feeder_cells_9.jpg\" alt=\"Feeder-free\" width=\"300px\"><\/p>\n<\/div>\n<p><a name=\"vol8\"><\/a><\/p>\n<hr \/>\n<h5>Attention to commonly used cell lines<\/h5>\n<p>Variable characteristics in human K-562 leukemia cell lines have often been overlooked. Commonly used cell lines may exhibit differences in their characteristics, even when they share the same name. Cell lines obtained from public cell banks can help ensure reproducibility, and publications should include both the registration number and the cell name.<br \/>\nKasai F, Mizukoshi K, Nakamura Y.<br \/>\n<strong>Variable characteristics overlooked in human K-562 leukemia cell lines with a common signature<\/strong>  <em>Sci Rep 2024<\/em> 14(1):9619<br \/>\nPubMed ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38671192\/\">38671192<\/a>   DOI: <a href=\"https:\/\/doi.org\/10.1038\/s41598-024-60271-8\">10.1038\/s41598-024-60271-8<\/a><br \/>\n<img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/images\/K562.jpg\" alt=\"K562\" width=\"150px\"><\/a><\/p>\n<p><a name=\"vol6\"><\/a><\/p>\n<hr \/>\n<h5>We are looking for the following requests from users of human iPS cells<\/h5>\n<ul>\n<li>Analysis of differentiation of certain iPS cell lines with micropatterning method<\/li>\n<li>Generation of a plasmid construct to express some marker gene (such as GFP) under the promoter of a specific gene<\/li>\n<li>Generation of a cell line in which a specific gene deletion (knockout) or a specific gene mutation is introduced in the iPS cells derived from healthy individuals etc.<\/li>\n<li>Repair of a causal gene mutation in certain disease-specific iPS cell line<\/li>\n<li>Adding whole genome information to the cell lines of the disease of your interest<\/li>\n<li>Analysis of whole genome regarding a certain group of disease-specific iPS cell lines<\/li>\n<\/ul>\n<p>Please contact us by E-mail (<a href=\"mailto:&#99;&#101;l&#108;ip&#x73;.br&#99;&#x40;&#x72;i&#x6b;e&#110;.&#x6a;p\">cellips.brc<img loading=\"lazy\" decoding=\"async\" title=\"\" alt=\"\" src=\"\/en\/wp-content\/uploads\/images\/at.png\" width=\"13\" height=\"13\" \/>riken.jp<\/a>).<\/p>\n<p><a name=\"vol5\"><\/a><\/p>\n<hr \/>\n<h5>Information of genetic analyses regarding disease-specific iPS cells<\/h5>\n<p>In relation to the disease-specific iPS cells derived from Amyotrophic Lateral Sclerosis (ALS), we analyzed two causal genes, SOD1 and TARDBP\/ALS10\/TDP-43. In relation to the iPS cells derived from Spinocerebellar degeneration, we analyzed the number of repeated sequences in 8 gene regions. The above results are available on the following pages.<br \/>\n<a href=\"\/en\/ga-als\">Genetic analysis of disease-specific iPS cells : Amyotrophic Lateral Sclerosis (ALS)<\/a><br \/>\n<img decoding=\"async\" src=\"https:\/\/cellbank.brc.riken.jp\/cell_bank\/Upload\/Images\/gazo\/HPS0476.jpg\" alt=\"HPS0476\" width=\"300px\"><\/p>\n<p><a href=\"\/en\/ga-scd\">Genetic analysis of disease-specific iPS cells : Spinocerebellar degeneration patients<\/a><br \/>\n<img decoding=\"async\" src=\"https:\/\/cellbank.brc.riken.jp\/cell_bank\/Upload\/Images\/gazo\/HPS1725.jpg\" alt=\"HPS1725\" width=\"300px\"><\/p>\n<p><a name=\"vol3\"><\/a><\/p>\n<hr \/>\n<h5>Reporter knock-in iPS cell lines<\/h5>\n<p>Reporter knock-in iPS cell lines made with CRISPR-Cas9 system are deposited to our cell bank.<br \/>\nBy using these cell lines, it is possible to visualize differentiation state of cells and analyze mechanisms of development.<br \/>\nH2B series resources are also useful for cell cycle research.<\/p>\n<ul>\n<li><a href=\"https:\/\/cellbank.brc.riken.jp\/cell_bank\/CellInfo\/?cellNo=HPS5064&#038;lang=En\">SOX10-TEZ(HPS5064)<\/a> [Parent: 201B7(HPS0063)] *TEZ: tdTomato, EF1, Zeocin<\/li>\n<li><a href=\"https:\/\/cellbank.brc.riken.jp\/cell_bank\/CellInfo\/?cellNo=HPS4903&#038;lang=En\">PAX6-TEZ (HPS4903)<\/a> [Parent: 454E2(HPS0077)]<\/li>\n<li><a href=\"https:\/\/cellbank.brc.riken.jp\/cell_bank\/CellInfo\/?cellNo=HPS5037&#038;lang=En\">ISL1-TEZ_1(HPS5037)<\/a> [Parent: 1383D6(HPS1006)]<\/li>\n<li><a href=\"https:\/\/cellbank.brc.riken.jp\/cell_bank\/CellInfo\/?cellNo=HPS5140&#038;lang=En\">H2B-TEZ(HPS5140)<\/a> [Parent: 1383D6(HPS1006)]<\/li>\n<li><a href=\"https:\/\/cellbank.brc.riken.jp\/cell_bank\/CellInfo\/?cellNo=HPS5141&#038;lang=En\">H2B-GEZ(HPS5141)<\/a> [Parent: 1383D6(HPS1006)] *GEZ: EGFP, EF1, Zeocin<\/li>\n<\/ul>\n<div>\n<p>\uff1cH2B-GFP\uff1e<\/p>\n<p><img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/images\/vol3_1.png\" alt=\"H2B-EGFP\" width=\"300px\"><img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/images\/vol3_2.png\" alt=\"H2B-GFP\" width=\"300px\"><img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/images\/vol3_3.png\" alt=\"H2B-GFP\" width=\"300px\"><\/p>\n<\/div>\n<div>\n<p>\uff1cH2B-tdTomato\uff1e<\/p>\n<p><img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/images\/vol3_4.png\" alt=\"H2B-tdTomato\" width=\"300px\"><img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/images\/vol3_5.png\" alt=\"H2B-tdTomato\" width=\"300px\"><img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/images\/vol3_6.png\" alt=\"H2B-tdTomato\" width=\"300px\"><\/p>\n<\/div>\n<p><a name=\"vol2\"><\/a><\/p>\n<hr \/>\n<h5><a href=\"\/en\/hps\/patient_specific_ips\">Human iPS cells derived from patients and healthy individuals<\/a><\/h5>\n<ul>\n<li>For providing most of the cell lines <u>neither<\/u> approval of the depositor <u>nor<\/u> research collaboration is required.<\/li>\n<li>We provide these iPS cells not only to the users in Japan, but also to the users in overseas, in addition, not only to not-for-profit intuitions but also to for-profit institutions.<\/li>\n<li>The iPS cells will be cultured on a priority basis upon requests.<\/li>\n<\/ul>\n<div class=\"gazo\">\n<img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/images\/feeder_free.jpg\" alt=\"Human iPS cells with feeder cells\" width=\"300px\"><\/p>\n<p>Human iPS cells with feeder cells<\/p>\n<\/div>\n<div class=\"gazo\">\n<img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/images\/feeder_cells.jpg\" alt=\"Feeder-free human iPS cells\" width=\"300px\"><\/p>\n<p>Feeder-free human iPS cells<\/p>\n<\/div>\n<p><a name=\"vol1\"><\/a><\/p>\n<hr \/>\n<h5><a href=\"\/en\/covid-19-related-cell-lone-resources\">Cell line resources for COVID-19 related research<\/a><\/h5>\n<p>We are providing hybridoma cell lines producing anti-SARS-CoV-2 Spike antibody.<br \/>\nMany papers have been published regarding COVID-19 related research in which the cell lines we had provided were used.<br \/>\nIn addition, many different kinds of cell lines in our bank have been used for viral infection research.<\/p>\n<div class=\"gazo\">\n<img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/images\/RCB5391.jpg\" alt=\"R52_Spike(RCB5391)\" width=\"300px\"><\/p>\n<p>R52_Spike(RCB5391)<\/p>\n<\/div>\n<div class=\"gazo\">\n<img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/images\/RCB0001.jpg\" alt=\"Vero(RCB0001)\" width=\"300px\"><\/p>\n<p>Vero(RCB0001)<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>BRC RESOURCE NEWS Archive FY2026 Training course for human iPS cells The training course for human iPS cells will be held. In this course, we will offer a lecture and practical training for human iPS cells including the overview of human iPS cell culture methods with passaging, freezing and resuscitation on feeder cells (vitrification method) as well as feeder-free culture methods in 1 day course. Please refer to our webpage for more information. https:\/\/web.brc.riken.jp\/en\/training We have a large collection of animal cell lines Our cell bank provides a wide range of animal cell lines for diverse research needs. Currently, we hold cell lines from about 40 animal species, including mink, enabling researchers to conveniently access the cells they require in one place. Mink\uff08RCB1833\uff09 FY2025 Training course for human iPS cells The training course for human iPS cells will be held. In this course, we will offer a lecture and practical training for human iPS cells including the overview of human iPS cell culture methods with passaging, freezing and resuscitation on feeder cells (vitrification method) as well as feeder-free culture methods in 1 day course. Please refer to our webpage for more information. https:\/\/web.brc.riken.jp\/en\/training We are looking for the requests from [&hellip;]<\/p>\n","protected":false},"author":14,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_seopress_analysis_target_kw":"","footnotes":"","_wp_rev_ctl_limit":""},"class_list":["post-10498","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/cell.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/10498","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/cell.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/cell.brc.riken.jp\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/cell.brc.riken.jp\/en\/wp-json\/wp\/v2\/users\/14"}],"replies":[{"embeddable":true,"href":"http:\/\/cell.brc.riken.jp\/en\/wp-json\/wp\/v2\/comments?post=10498"}],"version-history":[{"count":12,"href":"http:\/\/cell.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/10498\/revisions"}],"predecessor-version":[{"id":11265,"href":"http:\/\/cell.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/10498\/revisions\/11265"}],"wp:attachment":[{"href":"http:\/\/cell.brc.riken.jp\/en\/wp-json\/wp\/v2\/media?parent=10498"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}